 Acidosis, Renal Tubular
"Acidosis, Renal Tubular" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of genetic disorders of the KIDNEY TUBULES characterized by the accumulation of metabolically produced acids with elevated plasma chloride, hyperchloremic metabolic ACIDOSIS. Defective renal acidification of URINE (proximal tubules) or low renal acid excretion (distal tubules) can lead to complications such as HYPOKALEMIA, hypercalcinuria with NEPHROLITHIASIS and NEPHROCALCINOSIS, and RICKETS.
| Descriptor ID |
D000141
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| MeSH Number(s) |
C12.777.419.815.093 C13.351.968.419.815.093 C16.320.565.861.093 C18.452.076.176.210 C18.452.648.861.093
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| Concept/Terms |
Renal Tubular Acidosis, Type I- Renal Tubular Acidosis, Type I
- Acidosis, Renal Tubular, Type I
- Renal Tubular Acidosis, Distal, Autosomal Dominant
- Classic Distal Renal Tubular Acidosis
- Distal Renal Tubular Acidosis
- Type I Renal Tubular Acidosis
Renal Tubular Acidosis, Type II- Renal Tubular Acidosis, Type II
- Acidosis, Renal Tubular, Type II
- Renal Tubular Acidosis, Proximal, with Ocular Abnormalities
- Proximal Renal Tubular Acidosis
- Type II Renal Tubular Acidosis
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Below are MeSH descriptors whose meaning is more general than "Acidosis, Renal Tubular".
- Diseases [C]
- Male Urogenital Diseases [C12]
- Urologic Diseases [C12.777]
- Kidney Diseases [C12.777.419]
- Renal Tubular Transport, Inborn Errors [C12.777.419.815]
- Acidosis, Renal Tubular [C12.777.419.815.093]
- Female Urogenital Diseases and Pregnancy Complications [C13]
- Female Urogenital Diseases [C13.351]
- Urologic Diseases [C13.351.968]
- Kidney Diseases [C13.351.968.419]
- Renal Tubular Transport, Inborn Errors [C13.351.968.419.815]
- Acidosis, Renal Tubular [C13.351.968.419.815.093]
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
- Metabolism, Inborn Errors [C16.320.565]
- Renal Tubular Transport, Inborn Errors [C16.320.565.861]
- Acidosis, Renal Tubular [C16.320.565.861.093]
- Nutritional and Metabolic Diseases [C18]
- Metabolic Diseases [C18.452]
- Acid-Base Imbalance [C18.452.076]
- Acidosis [C18.452.076.176]
- Acidosis, Renal Tubular [C18.452.076.176.210]
- Metabolism, Inborn Errors [C18.452.648]
- Renal Tubular Transport, Inborn Errors [C18.452.648.861]
- Acidosis, Renal Tubular [C18.452.648.861.093]
Below are MeSH descriptors whose meaning is more specific than "Acidosis, Renal Tubular".
This graph shows the total number of publications written about "Acidosis, Renal Tubular" by people in this website by year, and whether "Acidosis, Renal Tubular" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 1 | 1 | 2 | | 1982 | 0 | 1 | 1 | | 1993 | 1 | 0 | 1 | | 2005 | 0 | 1 | 1 | | 2007 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Acidosis, Renal Tubular" by people in Profiles.
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Miller NL, Humphreys MR, Coe FL, Evan AP, Bledsoe SB, Handa SE, Lingeman JE. Nephrocalcinosis: re-defined in the era of endourology. Urol Res. 2010 Dec; 38(6):421-7.
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Evan AP, Lingeman J, Coe F, Shao Y, Miller N, Matlaga B, Phillips C, Sommer A, Worcester E. Renal histopathology of stone-forming patients with distal renal tubular acidosis. Kidney Int. 2007 Apr; 71(8):795-801.
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Li HC, Szigligeti P, Worrell RT, Matthews JB, Conforti L, Soleimani M. Missense mutations in Na+:HCO3- cotransporter NBC1 show abnormal trafficking in polarized kidney cells: a basis of proximal renal tubular acidosis. Am J Physiol Renal Physiol. 2005 Jul; 289(1):F61-71.
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Strife CF, Clardy CW, Varade WS, Prada AL, Waldo FB. Urine-to-blood carbon dioxide tension gradient and maximal depression of urinary pH to distinguish rate-dependent from classic distal renal tubular acidosis in children. J Pediatr. 1993 Jan; 122(1):60-5.
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Bushinsky DA, Coe FL, Katzenberg C, Szidon JP, Parks JH. Arterial PCO2 in chronic metabolic acidosis. Kidney Int. 1982 Sep; 22(3):311-4.
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Coe FL, Parks JH. Stone disease in hereditary distal renal tubular acidosis. Ann Intern Med. 1980 Jul; 93(1):60-1.
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Coe FL, Favus MJ. Treatment of renal calculi. Adv Intern Med. 1980; 26:373-92.
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Yamamoto T, Doi K, Ogihara T, Ichihara K, Hata T, Kumahara Y. Changes of blood pressure, plasma renin activity and plasma aldosterone concentration following the infusion of Sar1-Ile8-angiotensin II in hypertensive, fluid and electrolyte disorders. Prog Biochem Pharmacol. 1976; 12:174-89.
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Coe FL, Firpo JJ. Evidence for mild reversible hyperparathyroidism in distal renal tubular acidosis. Arch Intern Med. 1975 Nov; 135(11):1485-9.
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