"alpha-Glucosidases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze the exohydrolysis of 1,4-alpha-glucosidic linkages with release of alpha-glucose. Deficiency of alpha-1,4-glucosidase may cause GLYCOGEN STORAGE DISEASE TYPE II.
| Descriptor ID |
D000520
|
| MeSH Number(s) |
D08.811.277.450.420.050
|
| Concept/Terms |
alpha-Glucosidases- alpha-Glucosidases
- alpha Glucosidases
- Maltases
- alpha-Glucosidase
- alpha Glucosidase
- Maltase-Glucoamylase
- Maltase Glucoamylase
|
Below are MeSH descriptors whose meaning is more general than "alpha-Glucosidases".
Below are MeSH descriptors whose meaning is more specific than "alpha-Glucosidases".
This graph shows the total number of publications written about "alpha-Glucosidases" by people in this website by year, and whether "alpha-Glucosidases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "alpha-Glucosidases" by people in Profiles.
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Synthesis of Pyridine-Dicarboxamide-Cyclohexanone Derivatives: Anticancer and a-Glucosidase Inhibitory Activities and In Silico Study. Molecules. 2019 Apr 04; 24(7).
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Catalytic asymmetric synthesis of indole derivatives as novel a-glucosidase inhibitors in vitro. Bioorg Chem. 2018 09; 79:350-354.
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A Patient with a Novel Gene Mutation Leading to Autosomal Dominant Polycystic Kidney Disease. Clin J Am Soc Nephrol. 2017 10 06; 12(10):1695-1698.
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Mutations in GANAB, Encoding the Glucosidase IIa Subunit, Cause Autosomal-Dominant Polycystic Kidney and Liver Disease. Am J Hum Genet. 2016 06 02; 98(6):1193-1207.
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A concise synthesis and evaluation of new malonamide derivatives as potential a-glucosidase inhibitors. Bioorg Med Chem. 2016 Apr 15; 24(8):1675-82.
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Synthesis, in vitro biological activities and in silico study of dihydropyrimidines derivatives. Bioorg Med Chem. 2015 Oct 15; 23(20):6740-8.
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Novel catalytic mechanism of glycoside hydrolysis based on the structure of an NAD+/Mn2+ -dependent phospho-alpha-glucosidase from Bacillus subtilis. Structure. 2004 Sep; 12(9):1619-29.
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Decrease in mucosal alkaline phosphatase: a potential marker of intestinal reperfusion injury. J Lab Clin Med. 1999 Apr; 133(4):335-41.
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Transport of p-nitrophenyl-alpha-maltoside by the maltose transport system of Escherichia coli and its subsequent hydrolysis by a cytoplasmic alpha-maltosidase. J Bacteriol. 1986 Mar; 165(3):918-22.