 Aziridines
"Aziridines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Saturated azacyclopropane compounds. They include compounds with substitutions on CARBON or NITROGEN atoms.
| Descriptor ID |
D001388
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| MeSH Number(s) |
D03.383.097.217
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| Concept/Terms |
Aziridines- Aziridines
- Dimethyleneimines
- Ethyleneimines
- Azacyclopropanes, Saturated
- Saturated Azacyclopropanes
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Below are MeSH descriptors whose meaning is more general than "Aziridines".
Below are MeSH descriptors whose meaning is more specific than "Aziridines".
This graph shows the total number of publications written about "Aziridines" by people in this website by year, and whether "Aziridines" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1982 | 1 | 0 | 1 | | 1985 | 1 | 0 | 1 | | 1987 | 0 | 1 | 1 | | 1989 | 1 | 0 | 1 | | 2004 | 1 | 1 | 2 | | 2005 | 0 | 1 | 1 |
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Below are the most recent publications written about "Aziridines" by people in Profiles.
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Marcucci G, Mrózek K, Ruppert AS, Maharry K, Kolitz JE, Moore JO, Mayer RJ, Pettenati MJ, Powell BL, Edwards CG, Sterling LJ, Vardiman JW, Schiffer CA, Carroll AJ, Larson RA, Bloomfield CD. Prognostic factors and outcome of core binding factor acute myeloid leukemia patients with t(8;21) differ from those of patients with inv(16): a Cancer and Leukemia Group B study. J Clin Oncol. 2005 Aug 20; 23(24):5705-17.
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Farag SS, Ruppert AS, Mrózek K, Mayer RJ, Stone RM, Carroll AJ, Powell BL, Moore JO, Pettenati MJ, Koduru PR, Stamberg J, Baer MR, Block AW, Vardiman JW, Kolitz JE, Schiffer CA, Larson RA, Bloomfield CD. Outcome of induction and postremission therapy in younger adults with acute myeloid leukemia with normal karyotype: a cancer and leukemia group B study. J Clin Oncol. 2005 Jan 20; 23(3):482-93.
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Springer JB, Chang YH, Koo KI, Colvin OM, Colvin ME, Dolan ME, Delaney SM, Flowers JL, Ludeman SM. 1,3- vs 1,5-intramolecular alkylation reactions in isophosphoramide and phosphoramide mustards. Chem Res Toxicol. 2004 Sep; 17(9):1217-26.
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el Tamer A, Corey J, Wülfert E, Hanin I. Reversible cholinergic changes induced by AF64A in rat hippocampus and possible septal compensatory effect. Neuropharmacology. 1992 Apr; 31(4):397-402.
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Laganiere S, Marinko M, Corey J, Wulfert E, Hanin I. Sector-dependent neurotoxicity of ethylcholine aziridinium (AF64A) in the rat hippocampus. Neuropharmacology. 1990 Oct; 29(10):961-4.
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Harlow KW, Smith DN, Katzenellenbogen JA, Greene GL, Katzenellenbogen BS. Identification of cysteine 530 as the covalent attachment site of an affinity-labeling estrogen (ketononestrol aziridine) and antiestrogen (tamoxifen aziridine) in the human estrogen receptor. J Biol Chem. 1989 Oct 15; 264(29):17476-85.
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Schold SC, Mahaley MS, Vick NA, Friedman HS, Burger PC, DeLong ER, Albright RE, Bullard DE, Khandekar JD, Cairncross JG, et al. Phase II diaziquone-based chemotherapy trials in patients with anaplastic supratentorial astrocytic neoplasms. J Clin Oncol. 1987 Mar; 5(3):464-71.
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Haid M, Khandekar JD, Christ M, Johnson CM, Miller SJ, Locker GY, Merrill JM, Reisel H, Hatfield A, Lanzotti V, et al. Aziridinylbenzoquinone in recurrent, progressive glioma of the central nervous system. A Phase II study by the Illinois Cancer Council. Cancer. 1985 Sep 15; 56(6):1311-5.
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Schilsky RL, Kelley JA, Ihde DC, Howser DM, Cordes RS, Young RC. Phase I trial and pharmacokinetics of aziridinylbenzoquinone (NSC 182986) in humans. Cancer Res. 1982 Apr; 42(4):1582-6.
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