"Acetazolamide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Descriptor ID |
D000086
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MeSH Number(s) |
D02.886.675.867.060 D03.383.129.708.867.060
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Acetazolamide".
Below are MeSH descriptors whose meaning is more specific than "Acetazolamide".
This graph shows the total number of publications written about "Acetazolamide" by people in this website by year, and whether "Acetazolamide" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2011 | 0 | 1 | 1 |
2012 | 0 | 1 | 1 |
2015 | 1 | 0 | 1 |
2020 | 0 | 1 | 1 |
2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Acetazolamide" by people in Profiles.
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Development of direct compression Acetazolamide tablet with improved bioavailability in healthy human volunteers enabled by cocrystallization with p-Aminobenzoic acid. Int J Pharm. 2024 Mar 05; 652:123793.
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Influence of Acetazolamide on Hand Strength and Manual Dexterity During a 30-h Simulated High Altitude Exposure. Mil Med. 2020 08 14; 185(7-8):e1161-e1167.
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Acetazolamide reduces postoperative pain following laparoscopic inguinal herniorrhaphy. Surg Endosc. 2016 07; 30(7):2685-9.
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Spinocerebellar ataxia type 6. Handb Clin Neurol. 2012; 103:461-73.
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Headache and papilledema in an adult with cyanotic congenital heart disease: the importance of fundoscopic evaluation rather than phlebotomy. Congenit Heart Dis. 2012 May-Jun; 7(3):E14-7.
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Recent advances in obesity hypoventilation syndrome. Chest. 2007 Oct; 132(4):1322-36.
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Idiopathic intracranial hypertension and facial diplegia. Neurology. 1994 Feb; 44(2):357.
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Characteristics of apical Cl-HCO3 exchanger of bicarbonate-secreting cells in turtle bladder. Am J Physiol. 1990 Jan; 258(1 Pt 2):F9-14.
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Cellular contribution to pH-mediated calcium flux in neonatal mouse calvariae. Am J Physiol. 1985 Jun; 248(6 Pt 2):F785-9.
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Alkaline and acid transients in cerebellar microenvironment. J Neurophysiol. 1983 Mar; 49(3):831-50.