 Arylamine N-Acetyltransferase
"Arylamine N-Acetyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the transfer of acetyl groups from ACETYL-COA to arylamines. It can also catalyze acetyl transfer between arylamines without COENZYME A and has a wide specificity for aromatic amines, including SEROTONIN. However, arylamine N-acetyltransferase should not be confused with the enzyme ARYLALKYLAMINE N-ACETYLTRANSFERASE which is also referred to as SEROTONIN ACETYLTRANSFERASE.
| Descriptor ID |
D001191
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| MeSH Number(s) |
D08.811.913.050.313
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| Concept/Terms |
Arylamine N-Acetyltransferase- Arylamine N-Acetyltransferase
- Arylamine N Acetyltransferase
- N-Acetyltransferase, Arylamine
- Arylamine Acetyltransferases
- Acetyltransferases, Arylamine
- Arylamine Acetylases
- Acetylases, Arylamine
- Acetyl-CoA Arylamine N-Acetyltransferase
- Acetyl CoA Arylamine N Acetyltransferase
- Arylamine N-Acetyltransferase, Acetyl-CoA
- N-Acetyltransferase, Acetyl-CoA Arylamine
- Arylamine Acetylase
- Acetylase, Arylamine
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Below are MeSH descriptors whose meaning is more general than "Arylamine N-Acetyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Arylamine N-Acetyltransferase".
This graph shows the total number of publications written about "Arylamine N-Acetyltransferase" by people in this website by year, and whether "Arylamine N-Acetyltransferase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2012 | 1 | 1 | 2 | | 2019 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Arylamine N-Acetyltransferase" by people in Profiles.
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Ramirez J, House LK, Ratain MJ. Influence of N-acetyltransferase 2 gene polymorphisms on the in vitro metabolism of the epidermal growth factor receptor inhibitor rociletinib. Br J Clin Pharmacol. 2021 11; 87(11):4313-4322.
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Kotila OA, Fawole OI, Olopade OI, Ayede AI, Falusi AG, Babalola CP. N-acetyltransferase 2 enzyme genotype-phenotype discordances in both HIV-negative and HIV-positive Nigerians. Pharmacogenet Genomics. 2019 07; 29(5):106-113.
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Gibson TM, Smedby KE, Skibola CF, Hein DW, Slager SL, de Sanjosé S, Vajdic CM, Zhang Y, Chiu BC, Wang SS, Hjalgrim H, Nieters A, Bracci PM, Kricker A, Zheng T, Kolar C, Cerhan JR, Darabi H, Becker N, Conde L, Holford TR, Weisenburger DD, De Roos AJ, Butterbach K, Riby J, Cozen W, Benavente Y, Palmers C, Holly EA, Sampson JN, Rothman N, Armstrong BK, Morton LM. Smoking, variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2), and risk of non-Hodgkin lymphoma: a pooled analysis within the InterLymph consortium. Cancer Causes Control. 2013 Jan; 24(1):125-34.
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Aschebrook-Kilfoy B, Ollberding NJ, Kolar C, Lawson TA, Smith SM, Weisenburger DD, Chiu BC. Meat intake and risk of non-Hodgkin lymphoma. Cancer Causes Control. 2012 Oct; 23(10):1681-92.
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Li Y, Zheng T, Kilfoy BA, Lan Q, Holford T, Han X, Zhao P, Dai M, Leaderer B, Rothman N, Zhang Y. Genetic polymorphisms in cytochrome P450s, GSTs, NATs, alcohol consumption and risk of non-Hodgkin lymphoma. Am J Hematol. 2010 Mar; 85(3):213-5.
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Kilfoy BA, Zheng T, Lan Q, Han X, Holford T, Hein DW, Qin Q, Leaderer B, Morton LM, Yeager M, Boyle P, Zhao P, Chanock S, Rothman N, Zhang Y. Genetic variation in N-acetyltransferases 1 and 2, cigarette smoking, and risk of non-Hodgkin lymphoma. Cancer Causes Control. 2010 Jan; 21(1):127-33.
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Patin E, Barreiro LB, Sabeti PC, Austerlitz F, Luca F, Sajantila A, Behar DM, Semino O, Sakuntabhai A, Guiso N, Gicquel B, McElreavey K, Harding RM, Heyer E, Quintana-Murci L. Deciphering the ancient and complex evolutionary history of human arylamine N-acetyltransferase genes. Am J Hum Genet. 2006 Mar; 78(3):423-36.
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Faraglia B, Chen SY, Gammon MD, Zhang Y, Teitelbaum SL, Neugut AI, Ahsan H, Garbowski GC, Hibshoosh H, Lin D, Kadlubar FF, Santella RM. Evaluation of 4-aminobiphenyl-DNA adducts in human breast cancer: the influence of tobacco smoke. Carcinogenesis. 2003 Apr; 24(4):719-25.
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Maraganore DM, Farrer MJ, Hardy JA, McDonnell SK, Schaid DJ, Rocca WA. Case-control study of debrisoquine 4-hydroxylase, N-acetyltransferase 2, and apolipoprotein E gene polymorphisms in Parkinson's disease. Mov Disord. 2000 Jul; 15(4):714-9.
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Boddy AV, Ratain MJ. Pharmacogenetics in cancer etiology and chemotherapy. Clin Cancer Res. 1997 Jul; 3(7):1025-30.
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