 Chromosomes, Human, Pair 21
"Chromosomes, Human, Pair 21" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A specific pair of GROUP G CHROMOSOMES of the human chromosome classification.
| Descriptor ID |
D002891
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| MeSH Number(s) |
A11.284.187.520.300.505.510 G05.360.162.520.300.505.510
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Chromosomes, Human, Pair 21".
- Anatomy [A]
- Cells [A11]
- Cellular Structures [A11.284]
- Chromosomes [A11.284.187]
- Chromosomes, Mammalian [A11.284.187.520]
- Chromosomes, Human [A11.284.187.520.300]
- Chromosomes, Human, 21-22 and Y [A11.284.187.520.300.505]
- Chromosomes, Human, Pair 21 [A11.284.187.520.300.505.510]
- Biological Sciences [G]
- Genetic Phenomena [G05]
- Genetic Structures [G05.360]
- Chromosomes [G05.360.162]
- Chromosomes, Mammalian [G05.360.162.520]
- Chromosomes, Human [G05.360.162.520.300]
- Chromosomes, Human, 21-22 and Y [G05.360.162.520.300.505]
- Chromosomes, Human, Pair 21 [G05.360.162.520.300.505.510]
Below are MeSH descriptors whose meaning is more specific than "Chromosomes, Human, Pair 21".
This graph shows the total number of publications written about "Chromosomes, Human, Pair 21" by people in this website by year, and whether "Chromosomes, Human, Pair 21" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1987 | 1 | 0 | 1 | | 1990 | 1 | 0 | 1 | | 1992 | 2 | 0 | 2 | | 1993 | 3 | 2 | 5 | | 1994 | 1 | 0 | 1 | | 1995 | 1 | 1 | 2 | | 1996 | 1 | 3 | 4 | | 1997 | 1 | 2 | 3 | | 1998 | 1 | 0 | 1 | | 1999 | 2 | 0 | 2 | | 2000 | 1 | 0 | 1 | | 2001 | 2 | 0 | 2 | | 2002 | 4 | 0 | 4 | | 2003 | 0 | 2 | 2 | | 2004 | 1 | 1 | 2 | | 2006 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2015 | 1 | 1 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Chromosomes, Human, Pair 21" by people in Profiles.
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Li Z, Chen P, Su R, Li Y, Hu C, Wang Y, Arnovitz S, He M, Gurbuxani S, Zuo Z, Elkahloun AG, Li S, Weng H, Huang H, Neilly MB, Wang S, Olson EN, Larson RA, Le Beau MM, Zhang J, Jiang X, Wei M, Jin J, Liu PP, Chen J. Overexpression and knockout of miR-126 both promote leukemogenesis. Blood. 2015 Oct 22; 126(17):2005-15.
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Johnson RC, Weinberg OK, Cascio MJ, Dahl GV, Mitton BA, Silverman LB, Cherry AM, Arber DA, Ohgami RS. Cytogenetic Variation of B-Lymphoblastic Leukemia With Intrachromosomal Amplification of Chromosome 21 (iAMP21): A Multi-Institutional Series Review. Am J Clin Pathol. 2015 Jul; 144(1):103-12.
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Johnson RC, Savage NM, Chiang T, Gotlib JR, Cherry AM, Arber DA, George TI. Hidden mastocytosis in acute myeloid leukemia with t(8;21)(q22;q22). Am J Clin Pathol. 2013 Oct; 140(4):525-35.
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Malinge S, Bliss-Moreau M, Kirsammer G, Diebold L, Chlon T, Gurbuxani S, Crispino JD. Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome. J Clin Invest. 2012 Mar; 122(3):948-62.
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Gertz J, Varley KE, Reddy TE, Bowling KM, Pauli F, Parker SL, Kucera KS, Willard HF, Myers RM. Analysis of DNA methylation in a three-generation family reveals widespread genetic influence on epigenetic regulation. PLoS Genet. 2011 Aug; 7(8):e1002228.
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Terao C, Yamada R, Ohmura K, Takahashi M, Kawaguchi T, Kochi Y. The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population. Hum Mol Genet. 2011 Jul 01; 20(13):2680-5.
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Fledel-Alon A, Wilson DJ, Broman K, Wen X, Ober C, Coop G, Przeworski M. Broad-scale recombination patterns underlying proper disjunction in humans. PLoS Genet. 2009 Sep; 5(9):e1000658.
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Dobyns WB, Mirzaa G, Christian SL, Petras K, Roseberry J, Clark GD, Curry CJ, McDonald-McGinn D, Medne L, Zackai E, Parsons J, Zand DJ, Hisama FM, Walsh CA, Leventer RJ, Martin CL, Gajecka M, Shaffer LG. Consistent chromosome abnormalities identify novel polymicrogyria loci in 1p36.3, 2p16.1-p23.1, 4q21.21-q22.1, 6q26-q27, and 21q2. Am J Med Genet A. 2008 Jul 01; 146A(13):1637-54.
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Kirsammer G, Jilani S, Liu H, Davis E, Gurbuxani S, Le Beau MM, Crispino JD. Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome. Blood. 2008 Jan 15; 111(2):767-75.
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Nguyen TT, Ma LN, Slovak ML, Bangs CD, Cherry AM, Arber DA. Identification of novel Runx1 (AML1) translocation partner genes SH3D19, YTHDf2, and ZNF687 in acute myeloid leukemia. Genes Chromosomes Cancer. 2006 Oct; 45(10):918-32.
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