The University of Chicago Header Logo

Mary Sara McPeek

TitleProfessor
InstitutionUniversity of Chicago
DepartmentStatistics
AddressChicago IL 60637
Email
vCardDownload vCard

    Collapse Research 
    Collapse research activities and funding
    R01HG001645     (MCPEEK, MARY SARA)Sep 1, 1997 - May 31, 2024
    NIH
    Methods for Human Genetic Mapping
    Role: Principal Investigator
    R29HG001645     (MCPEEK, MARY SARA)Sep 1, 1997 - Feb 8, 2003
    NIH
    METHODS FOR HUMAN GENETIC LINKAGE MAPPING
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Wang M, Roux F, Bartoli C, Huard-Chauveau C, Meyer C, Lee H, Roby D, McPeek MS, Bergelson J, Wang M, Roux F, Bartoli C, Huard-Chauveau C, Meyer C, Lee H, Roby D, McPeek MS, Bergelson J. Two-way mixed-effects methods for joint association analysis using both host and pathogen genomes. Proc Natl Acad Sci U S A. 2018 06 12; 115(24):E5440-E5449. PMID: 29848634; PMCID: PMC6004472.
      Citations: 19     Fields:    Translation:AnimalsCells
    2. Wu X, McPeek MS, Wu X, McPeek MS. L-GATOR: Genetic Association Testing for a Longitudinally Measured Quantitative Trait in Samples with Related Individuals. Am J Hum Genet. 2018 04 05; 102(4):574-591. PMID: 29625022; PMCID: PMC5985289.
      Citations: 1     Fields:    Translation:Humans
    3. Zhong S, Jiang D, McPeek MS, Zhong S, Jiang D, McPeek MS. CERAMIC: Case-Control Association Testing in Samples with Related Individuals, Based on Retrospective Mixed Model Analysis with Adjustment for Covariates. PLoS Genet. 2016 Oct; 12(10):e1006329. PMID: 27695091; PMCID: PMC5047592.
      Citations: 7     Fields:    Translation:Humans
    4. Jiang D, Mbatchou J, McPeek MS, Jiang D, Mbatchou J, McPeek MS. Retrospective Association Analysis of Binary Traits: Overcoming Some Limitations of the Additive Polygenic Model. Hum Hered. 2015; 80(4):187-95. PMID: 27576759; PMCID: PMC5505235.
      Citations: 3     Fields:    Translation:Humans
    5. Wang M, Jakobsdottir J, Smith AV, McPeek MS, Wang M, Jakobsdottir J, Smith AV, McPeek MS. G-STRATEGY: Optimal Selection of Individuals for Sequencing in Genetic Association Studies. Genet Epidemiol. 2016 09; 40(6):446-60. PMID: 27256766; PMCID: PMC5473612.
      Citations:    Fields:    Translation:Humans
    6. Jiang D, Zhong S, McPeek MS, Jiang D, Zhong S, McPeek MS. Retrospective Binary-Trait Association Test Elucidates Genetic Architecture of Crohn Disease. Am J Hum Genet. 2016 Feb 04; 98(2):243-55. PMID: 26833331; PMCID: PMC4746383.
      Citations: 12     Fields:    Translation:Humans
    7. Jiang D, McPeek MS, Jiang D, McPeek MS. Robust rare variant association testing for quantitative traits in samples with related individuals. Genet Epidemiol. 2014 Jan; 38(1):10-20. PMID: 24248908; PMCID: PMC4510991.
      Citations: 33     Fields:    Translation:Humans
    8. Jakobsdottir J, McPeek MS, Jakobsdottir J, McPeek MS. MASTOR: mixed-model association mapping of quantitative traits in samples with related individuals. Am J Hum Genet. 2013 May 02; 92(5):652-66. PMID: 23643379; PMCID: PMC3644644.
      Citations: 21     Fields:    Translation:Humans
    9. McPeek MS, McPeek MS. BLUP genotype imputation for case-control association testing with related individuals and missing data. J Comput Biol. 2012 Jun; 19(6):756-65. PMID: 22697245; PMCID: PMC3375641.
      Citations: 10     Fields:    Translation:Humans
    10. Thornton T, Zhang Q, Cai X, Ober C, McPeek MS, Thornton T, Zhang Q, Cai X, Ober C, McPeek MS. XM: association testing on the X-chromosome in case-control samples with related individuals. Genet Epidemiol. 2012 Jul; 36(5):438-50. PMID: 22552845; PMCID: PMC3762984.
      Citations: 15     Fields:    Translation:HumansCells
    11. Thornton T, McPeek MS, Thornton T, McPeek MS. ROADTRIPS: case-control association testing with partially or completely unknown population and pedigree structure. Am J Hum Genet. 2010 Feb 12; 86(2):172-84. PMID: 20137780; PMCID: PMC2820184.
      Citations: 90     Fields:    Translation:Humans
    12. Zhang J, Niyogi P, McPeek MS, Zhang J, Niyogi P, McPeek MS. Laplacian eigenfunctions learn population structure. PLoS One. 2009 Dec 01; 4(12):e7928. PMID: 19956572; PMCID: PMC2779848.
      Citations: 16     Fields:    Translation:Animals
    13. Wang Z, McPeek MS, Wang Z, McPeek MS. ATRIUM: testing untyped SNPs in case-control association studies with related individuals. Am J Hum Genet. 2009 Nov; 85(5):667-78. PMID: 19913122; PMCID: PMC2775837.
      Citations: 5     Fields:    Translation:HumansCells
    14. Wang Z, McPeek MS, Wang Z, McPeek MS. An Incomplete-Data Quasi-likelihood Approach to Haplotype-Based Genetic Association Studies on Related Individuals. J Am Stat Assoc. 2009 09 01; 104(487):1251-1260. PMID: 20428335; PMCID: PMC2860453.
      Citations: 10     
    15. Wang HY, Fu Y, McPeek MS, Lu X, Nuzhdin S, Xu A, Lu J, Wu ML, Wu CI, Wang HY, Fu Y, McPeek MS, Lu X, Nuzhdin S, Xu A, Lu J, Wu ML, Wu CI. Complex genetic interactions underlying expression differences between Drosophila races: analysis of chromosome substitutions. Proc Natl Acad Sci U S A. 2008 Apr 29; 105(17):6362-7. PMID: 18430800; PMCID: PMC2359775.
      Citations: 21     Fields:    Translation:AnimalsCells
    16. Thornton T, McPeek MS, Thornton T, McPeek MS. Case-control association testing with related individuals: a more powerful quasi-likelihood score test. Am J Hum Genet. 2007 Aug; 81(2):321-37. PMID: 17668381; PMCID: PMC1950805.
      Citations: 111     Fields:    Translation:Humans
    17. Pluzhnikov A, Nolan DK, Tan Z, McPeek MS, Ober C, Pluzhnikov A, Nolan DK, Tan Z, McPeek MS, Ober C. Correlation of intergenerational family sizes suggests a genetic component of reproductive fitness. Am J Hum Genet. 2007 Jul; 81(1):165-9. PMID: 17564973; PMCID: PMC1950912.
      Citations: 10     Fields:    Translation:Humans
    18. Tong L, Mets L, McPeek MS, Tong L, Mets L, McPeek MS. Likelihood-based inference for multi-color optical mapping. Stat Appl Genet Mol Biol. 2007; 6:Article5. PMID: 17402920.
      Citations: 1     Fields:    Translation:Cells
    19. Zheng M, McPeek MS, Zheng M, McPeek MS. Multipoint linkage-disequilibrium mapping with haplotype-block structure. Am J Hum Genet. 2007 Jan; 80(1):112-25. PMID: 17160899; PMCID: PMC1785316.
      Citations: 7     Fields:    Translation:Humans
    20. Armstrong NJ, McPeek MS, Speed TP, Armstrong NJ, McPeek MS, Speed TP. Incorporating interference into linkage analysis for experimental crosses. Biostatistics. 2006 Jul; 7(3):374-86. PMID: 16354713.
      Citations:    Fields:    Translation:Animals
    21. Zhang J, Schneider D, Ober C, McPeek MS, Zhang J, Schneider D, Ober C, McPeek MS. Multilocus linkage disequilibrium mapping by the decay of haplotype sharing with samples of related individuals. Genet Epidemiol. 2005 Sep; 29(2):128-40. PMID: 16049966.
      Citations: 3     Fields:    Translation:Humans
    22. Weiss LA, Veenstra-Vanderweele J, Newman DL, Kim SJ, Dytch H, McPeek MS, Cheng S, Ober C, Cook EH, Abney M, Weiss LA, Veenstra-Vanderweele J, Newman DL, Kim SJ, Dytch H, McPeek MS, Cheng S, Ober C, Cook EH, Abney M. Genome-wide association study identifies ITGB3 as a QTL for whole blood serotonin. Eur J Hum Genet. 2004 Nov; 12(11):949-54. PMID: 15292919.
      Citations: 33     Fields:    Translation:HumansCells
    23. Bourgain C, Abney M, Schneider D, Ober C, McPeek MS, Bourgain C, Abney M, Schneider D, Ober C, McPeek MS. Testing for Hardy-Weinberg equilibrium in samples with related individuals. Genetics. 2004 Dec; 168(4):2349-61. PMID: 15371359; PMCID: PMC1448754.
      Citations: 27     Fields:    
    24. Newman DL, Hoffjan S, Bourgain C, Abney M, Nicolae RI, Profits ET, Grow MA, Walker K, Steiner L, Parry R, Reynolds R, McPeek MS, Cheng S, Ober C, Newman DL, Hoffjan S, Bourgain C, Abney M, Nicolae RI, Profits ET, Grow MA, Walker K, Steiner L, Parry R, Reynolds R, McPeek MS, Cheng S, Ober C. Are common disease susceptibility alleles the same in outbred and founder populations? Eur J Hum Genet. 2004 Jul; 12(7):584-90. PMID: 15100713.
      Citations: 17     Fields:    Translation:Humans
    25. McPeek MS, Wu X, Ober C, McPeek MS, Wu X, Ober C. Best linear unbiased allele-frequency estimation in complex pedigrees. Biometrics. 2004 Jun; 60(2):359-67. PMID: 15180661.
      Citations: 54     Fields:    Translation:Humans
    26. Bourgain C, Hoffjan S, Nicolae R, Newman D, Steiner L, Walker K, Reynolds R, Ober C, McPeek MS, Bourgain C, Hoffjan S, Nicolae R, Newman D, Steiner L, Walker K, Reynolds R, Ober C, McPeek MS. Novel case-control test in a founder population identifies P-selectin as an atopy-susceptibility locus. Am J Hum Genet. 2003 Sep; 73(3):612-26. PMID: 12929084; PMCID: PMC1180685.
      Citations: 84     Fields:    Translation:Humans
    27. Newman DL, Abney M, Dytch H, Parry R, McPeek MS, Ober C, Newman DL, Abney M, Dytch H, Parry R, McPeek MS, Ober C. Major loci influencing serum triglyceride levels on 2q14 and 9p21 localized by homozygosity-by-descent mapping in a large Hutterite pedigree. Hum Mol Genet. 2003 Jan 15; 12(2):137-44. PMID: 12499394.
      Citations: 18     Fields:    Translation:HumansCells
    28. Abney M, Ober C, McPeek MS, Abney M, Ober C, McPeek MS. Quantitative-trait homozygosity and association mapping and empirical genomewide significance in large, complex pedigrees: fasting serum-insulin level in the Hutterites. Am J Hum Genet. 2002 Apr; 70(4):920-34. PMID: 11880950; PMCID: PMC379120.
      Citations: 70     Fields:    Translation:HumansCells
    29. Sun L, Cox NJ, McPeek MS, Sun L, Cox NJ, McPeek MS. A statistical method for identification of polymorphisms that explain a linkage result. Am J Hum Genet. 2002 Feb; 70(2):399-411. PMID: 11791210; PMCID: PMC526471.
      Citations: 25     Fields:    Translation:HumansCells
    30. Sun L, Wilder K, McPeek MS, Sun L, Wilder K, McPeek MS. Enhanced pedigree error detection. Hum Hered. 2002; 54(2):99-110. PMID: 12566741.
      Citations: 82     Fields:    Translation:Humans
    31. Newman DL, Abney M, McPeek MS, Ober C, Cox NJ, Newman DL, Abney M, McPeek MS, Ober C, Cox NJ. The importance of genealogy in determining genetic associations with complex traits. Am J Hum Genet. 2001 Nov; 69(5):1146-8. PMID: 11590549; PMCID: PMC1274359.
      Citations: 38     Fields:    Translation:Humans
    32. Ober C, Abney M, McPeek MS, Ober C, Abney M, McPeek MS. The genetic dissection of complex traits in a founder population. Am J Hum Genet. 2001 Nov; 69(5):1068-79. PMID: 11590547; PMCID: PMC1274354.
      Citations: 78     Fields:    Translation:HumansCells
    33. Abney M, McPeek MS, Ober C, Abney M, McPeek MS, Ober C. Broad and narrow heritabilities of quantitative traits in a founder population. Am J Hum Genet. 2001 May; 68(5):1302-7. PMID: 11309690; PMCID: PMC1226113.
      Citations: 67     Fields:    Translation:Humans
    34. Sun L, Abney M, McPeek MS, Sun L, Abney M, McPeek MS. Detection of mis-specified relationships in inbred and outbred pedigrees. Genet Epidemiol. 2001; 21 Suppl 1:S36-41. PMID: 11793699.
      Citations: 6     Fields:    Translation:Humans
    35. McPeek MS, McPeek MS. From mouse to human: fine mapping of quantitative trait loci in a model organism. Proc Natl Acad Sci U S A. 2000 Nov 07; 97(23):12389-90. PMID: 11050190; PMCID: PMC34053.
      Citations: 9     Fields:    Translation:HumansAnimals
    36. McPeek MS, Sun L, McPeek MS, Sun L. Statistical tests for detection of misspecified relationships by use of genome-screen data. Am J Hum Genet. 2000 Mar; 66(3):1076-94. PMID: 10712219; PMCID: PMC1288143.
      Citations: 164     Fields:    Translation:HumansCells
    37. Abney M, McPeek MS, Ober C, Abney M, McPeek MS, Ober C. Estimation of variance components of quantitative traits in inbred populations. Am J Hum Genet. 2000 Feb; 66(2):629-50. PMID: 10677322; PMCID: PMC1288115.
      Citations: 58     Fields:    Translation:Humans
    38. Girardet A, McPeek MS, Leeflang EP, Munier F, Arnheim N, Claustres M, Pellestor F, Girardet A, McPeek MS, Leeflang EP, Munier F, Arnheim N, Claustres M, Pellestor F. Meiotic segregation analysis of RB1 alleles in retinoblastoma pedigrees by use of single-sperm typing. Am J Hum Genet. 2000 Jan; 66(1):167-75. PMID: 10631148; PMCID: PMC1288323.
      Citations: 2     Fields:    Translation:HumansCells
    39. McPeek MS, McPeek MS. SPERMSEG: analysis of segregation distortion in single-sperm data. Am J Hum Genet. 1999 Oct; 65(4):1195-7. PMID: 10486338; PMCID: PMC1288252.
      Citations: 2     Fields:    Translation:HumansCells
    40. Grewal RP, Cancel G, Leeflang EP, D?rr A, McPeek MS, Draghinas D, Yao X, Stevanin G, Alnot MO, Brice A, Arnheim N, Grewal RP, Cancel G, Leeflang EP, D?rr A, McPeek MS, Draghinas D, Yao X, Stevanin G, Alnot MO, Brice A, Arnheim N. French Machado-Joseph disease patients do not exhibit gametic segregation distortion: a sperm typing analysis. Hum Mol Genet. 1999 Sep; 8(9):1779-84. PMID: 10441343.
      Citations: 7     Fields:    Translation:HumansCells
    41. McPeek MS, Strahs A, McPeek MS, Strahs A. Assessment of linkage disequilibrium by the decay of haplotype sharing, with application to fine-scale genetic mapping. Am J Hum Genet. 1999 Sep; 65(3):858-75. PMID: 10445904; PMCID: PMC1378001.
      Citations: 75     Fields:    Translation:Humans
    42. McPeek MS, McPeek MS. Optimal allele-sharing statistics for genetic mapping using affected relatives. Genet Epidemiol. 1999; 16(3):225-49. PMID: 10096687.
      Citations: 25     Fields:    Translation:Humans
    43. Leeflang EP, McPeek MS, Arnheim N, Leeflang EP, McPeek MS, Arnheim N. Analysis of meiotic segregation, using single-sperm typing: meiotic drive at the myotonic dystrophy locus. Am J Hum Genet. 1996 Oct; 59(4):896-904. PMID: 8808606; PMCID: PMC1914809.
      Citations: 9     Fields:    Translation:HumansCells
    44. McPeek MS, Speed TP, McPeek MS, Speed TP. Modeling interference in genetic recombination. Genetics. 1995 Feb; 139(2):1031-44. PMID: 7713406; PMCID: PMC1206354.
      Citations: 80     Fields:    Translation:Animals
    45. Zhao H, McPeek MS, Speed TP, Zhao H, McPeek MS, Speed TP. Statistical analysis of chromatid interference. Genetics. 1995 Feb; 139(2):1057-65. PMID: 7713408; PMCID: PMC1206356.
      Citations: 34     Fields:    Translation:AnimalsCells
    46. Zhao H, Speed TP, McPeek MS, Zhao H, Speed TP, McPeek MS. Statistical analysis of crossover interference using the chi-square model. Genetics. 1995 Feb; 139(2):1045-56. PMID: 7713407; PMCID: PMC1206355.
      Citations: 42     Fields:    Translation:HumansAnimals
    47. Scherer S, McPeek MS, Speed TP, Scherer S, McPeek MS, Speed TP. Atypical regions in large genomic DNA sequences. Proc Natl Acad Sci U S A. 1994 Jul 19; 91(15):7134-8. PMID: 8041759; PMCID: PMC44353.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    48. Speed TP, McPeek MS, Evans SN, Speed TP, McPeek MS, Evans SN. Robustness of the no-interference model for ordering genetic markers. Proc Natl Acad Sci U S A. 1992 Apr 01; 89(7):3103-6. PMID: 1557418; PMCID: PMC48812.
      Citations: 6     Fields:    Translation:Cells
    49. Guerra R, McPeek MS, Speed TP, Stewart PM, Guerra R, McPeek MS, Speed TP, Stewart PM. A Bayesian analysis for mapping from radiation hybrid data. Cytogenet Cell Genet. 1992; 59(2-3):104-6. PMID: 1737469.
      Citations:    Fields:    Translation:HumansCells
    McPeek's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (182)
    Explore
    _
    Co-Authors (6)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _
    Physical Neighbors
    _