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Last Name
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Mary Sara McPeek

TitleProfessor
InstitutionUniversity of Chicago
DepartmentStatistics
AddressChicago IL 60637
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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Wang M, Roux F, Bartoli C, Huard-Chauveau C, Meyer C, Lee H, Roby D, McPeek MS, Bergelson J. Two-way mixed-effects methods for joint association analysis using both host and pathogen genomes. Proc Natl Acad Sci U S A. 2018 06 12; 115(24):E5440-E5449. PMID: 29848634.
      View in: PubMed
    2. Wu X, McPeek MS. L-GATOR: Genetic Association Testing for a Longitudinally Measured Quantitative Trait in Samples with Related Individuals. Am J Hum Genet. 2018 04 05; 102(4):574-591. PMID: 29625022.
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    3. Zhong S, Jiang D, McPeek MS. CERAMIC: Case-Control Association Testing in Samples with Related Individuals, Based on Retrospective Mixed Model Analysis with Adjustment for Covariates. PLoS Genet. 2016 Oct; 12(10):e1006329. PMID: 27695091.
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    4. Jiang D, Mbatchou J, McPeek MS. Retrospective Association Analysis of Binary Traits: Overcoming Some Limitations of the Additive Polygenic Model. Hum Hered. 2015; 80(4):187-95. PMID: 27576759.
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    5. Wang M, Jakobsdottir J, Smith AV, McPeek MS. G-STRATEGY: Optimal Selection of Individuals for Sequencing in Genetic Association Studies. Genet Epidemiol. 2016 09; 40(6):446-60. PMID: 27256766.
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    6. Jiang D, Zhong S, McPeek MS. Retrospective Binary-Trait Association Test Elucidates Genetic Architecture of Crohn Disease. Am J Hum Genet. 2016 Feb 04; 98(2):243-55. PMID: 26833331.
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    7. Jiang D, McPeek MS. Robust rare variant association testing for quantitative traits in samples with related individuals. Genet Epidemiol. 2014 Jan; 38(1):10-20. PMID: 24248908.
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    8. Jakobsdottir J, McPeek MS. MASTOR: mixed-model association mapping of quantitative traits in samples with related individuals. Am J Hum Genet. 2013 May 02; 92(5):652-66. PMID: 23643379.
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    9. McPeek MS. BLUP genotype imputation for case-control association testing with related individuals and missing data. J Comput Biol. 2012 Jun; 19(6):756-65. PMID: 22697245.
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    10. Thornton T, Zhang Q, Cai X, Ober C, McPeek MS. XM: association testing on the X-chromosome in case-control samples with related individuals. Genet Epidemiol. 2012 Jul; 36(5):438-50. PMID: 22552845.
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    11. Thornton T, McPeek MS. ROADTRIPS: case-control association testing with partially or completely unknown population and pedigree structure. Am J Hum Genet. 2010 Feb 12; 86(2):172-84. PMID: 20137780.
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    12. Zhang J, Niyogi P, McPeek MS. Laplacian eigenfunctions learn population structure. PLoS One. 2009 Dec 01; 4(12):e7928. PMID: 19956572.
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    13. Wang Z, McPeek MS. ATRIUM: testing untyped SNPs in case-control association studies with related individuals. Am J Hum Genet. 2009 Nov; 85(5):667-78. PMID: 19913122.
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    14. Wang Z, McPeek MS. An Incomplete-Data Quasi-likelihood Approach to Haplotype-Based Genetic Association Studies on Related Individuals. J Am Stat Assoc. 2009 09 01; 104(487):1251-1260. PMID: 20428335.
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    15. Wang HY, Fu Y, McPeek MS, Lu X, Nuzhdin S, Xu A, Lu J, Wu ML, Wu CI. Complex genetic interactions underlying expression differences between Drosophila races: analysis of chromosome substitutions. Proc Natl Acad Sci U S A. 2008 Apr 29; 105(17):6362-7. PMID: 18430800.
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    16. Thornton T, McPeek MS. Case-control association testing with related individuals: a more powerful quasi-likelihood score test. Am J Hum Genet. 2007 Aug; 81(2):321-37. PMID: 17668381.
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    17. Pluzhnikov A, Nolan DK, Tan Z, McPeek MS, Ober C. Correlation of intergenerational family sizes suggests a genetic component of reproductive fitness. Am J Hum Genet. 2007 Jul; 81(1):165-9. PMID: 17564973.
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    18. Tong L, Mets L, McPeek MS. Likelihood-based inference for multi-color optical mapping. Stat Appl Genet Mol Biol. 2007; 6:Article5. PMID: 17402920.
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    19. Zheng M, McPeek MS. Multipoint linkage-disequilibrium mapping with haplotype-block structure. Am J Hum Genet. 2007 Jan; 80(1):112-25. PMID: 17160899.
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    20. Armstrong NJ, McPeek MS, Speed TP. Incorporating interference into linkage analysis for experimental crosses. Biostatistics. 2006 Jul; 7(3):374-86. PMID: 16354713.
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    21. Zhang J, Schneider D, Ober C, McPeek MS. Multilocus linkage disequilibrium mapping by the decay of haplotype sharing with samples of related individuals. Genet Epidemiol. 2005 Sep; 29(2):128-40. PMID: 16049966.
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    22. Weiss LA, Veenstra-Vanderweele J, Newman DL, Kim SJ, Dytch H, McPeek MS, Cheng S, Ober C, Cook EH, Abney M. Genome-wide association study identifies ITGB3 as a QTL for whole blood serotonin. Eur J Hum Genet. 2004 Nov; 12(11):949-54. PMID: 15292919.
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    23. Bourgain C, Abney M, Schneider D, Ober C, McPeek MS. Testing for Hardy-Weinberg equilibrium in samples with related individuals. Genetics. 2004 Dec; 168(4):2349-61. PMID: 15371359.
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    24. Newman DL, Hoffjan S, Bourgain C, Abney M, Nicolae RI, Profits ET, Grow MA, Walker K, Steiner L, Parry R, Reynolds R, McPeek MS, Cheng S, Ober C. Are common disease susceptibility alleles the same in outbred and founder populations? Eur J Hum Genet. 2004 Jul; 12(7):584-90. PMID: 15100713.
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    25. McPeek MS, Wu X, Ober C. Best linear unbiased allele-frequency estimation in complex pedigrees. Biometrics. 2004 Jun; 60(2):359-67. PMID: 15180661.
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    26. Bourgain C, Hoffjan S, Nicolae R, Newman D, Steiner L, Walker K, Reynolds R, Ober C, McPeek MS. Novel case-control test in a founder population identifies P-selectin as an atopy-susceptibility locus. Am J Hum Genet. 2003 Sep; 73(3):612-26. PMID: 12929084.
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    27. Newman DL, Abney M, Dytch H, Parry R, McPeek MS, Ober C. Major loci influencing serum triglyceride levels on 2q14 and 9p21 localized by homozygosity-by-descent mapping in a large Hutterite pedigree. Hum Mol Genet. 2003 Jan 15; 12(2):137-44. PMID: 12499394.
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    28. Abney M, Ober C, McPeek MS. Quantitative-trait homozygosity and association mapping and empirical genomewide significance in large, complex pedigrees: fasting serum-insulin level in the Hutterites. Am J Hum Genet. 2002 Apr; 70(4):920-34. PMID: 11880950.
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    29. Sun L, Cox NJ, McPeek MS. A statistical method for identification of polymorphisms that explain a linkage result. Am J Hum Genet. 2002 Feb; 70(2):399-411. PMID: 11791210.
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    30. Sun L, Wilder K, McPeek MS. Enhanced pedigree error detection. Hum Hered. 2002; 54(2):99-110. PMID: 12566741.
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    31. Newman DL, Abney M, McPeek MS, Ober C, Cox NJ. The importance of genealogy in determining genetic associations with complex traits. Am J Hum Genet. 2001 Nov; 69(5):1146-8. PMID: 11590549.
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    32. Ober C, Abney M, McPeek MS. The genetic dissection of complex traits in a founder population. Am J Hum Genet. 2001 Nov; 69(5):1068-79. PMID: 11590547.
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    33. Abney M, McPeek MS, Ober C. Broad and narrow heritabilities of quantitative traits in a founder population. Am J Hum Genet. 2001 May; 68(5):1302-7. PMID: 11309690.
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    34. Sun L, Abney M, McPeek MS. Detection of mis-specified relationships in inbred and outbred pedigrees. Genet Epidemiol. 2001; 21 Suppl 1:S36-41. PMID: 11793699.
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    35. McPeek MS. From mouse to human: fine mapping of quantitative trait loci in a model organism. Proc Natl Acad Sci U S A. 2000 Nov 07; 97(23):12389-90. PMID: 11050190.
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    36. McPeek MS, Sun L. Statistical tests for detection of misspecified relationships by use of genome-screen data. Am J Hum Genet. 2000 Mar; 66(3):1076-94. PMID: 10712219.
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    37. Abney M, McPeek MS, Ober C. Estimation of variance components of quantitative traits in inbred populations. Am J Hum Genet. 2000 Feb; 66(2):629-50. PMID: 10677322.
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    38. Girardet A, McPeek MS, Leeflang EP, Munier F, Arnheim N, Claustres M, Pellestor F. Meiotic segregation analysis of RB1 alleles in retinoblastoma pedigrees by use of single-sperm typing. Am J Hum Genet. 2000 Jan; 66(1):167-75. PMID: 10631148.
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    39. McPeek MS. SPERMSEG: analysis of segregation distortion in single-sperm data. Am J Hum Genet. 1999 Oct; 65(4):1195-7. PMID: 10486338.
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    40. Grewal RP, Cancel G, Leeflang EP, Dürr A, McPeek MS, Draghinas D, Yao X, Stevanin G, Alnot MO, Brice A, Arnheim N. French Machado-Joseph disease patients do not exhibit gametic segregation distortion: a sperm typing analysis. Hum Mol Genet. 1999 Sep; 8(9):1779-84. PMID: 10441343.
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    41. McPeek MS, Strahs A. Assessment of linkage disequilibrium by the decay of haplotype sharing, with application to fine-scale genetic mapping. Am J Hum Genet. 1999 Sep; 65(3):858-75. PMID: 10445904.
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    42. McPeek MS. Optimal allele-sharing statistics for genetic mapping using affected relatives. Genet Epidemiol. 1999; 16(3):225-49. PMID: 10096687.
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    43. Leeflang EP, McPeek MS, Arnheim N. Analysis of meiotic segregation, using single-sperm typing: meiotic drive at the myotonic dystrophy locus. Am J Hum Genet. 1996 Oct; 59(4):896-904. PMID: 8808606.
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    44. Zhao H, Speed TP, McPeek MS. Statistical analysis of crossover interference using the chi-square model. Genetics. 1995 Feb; 139(2):1045-56. PMID: 7713407.
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    45. McPeek MS, Speed TP. Modeling interference in genetic recombination. Genetics. 1995 Feb; 139(2):1031-44. PMID: 7713406.
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    46. Zhao H, McPeek MS, Speed TP. Statistical analysis of chromatid interference. Genetics. 1995 Feb; 139(2):1057-65. PMID: 7713408.
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    47. Scherer S, McPeek MS, Speed TP. Atypical regions in large genomic DNA sequences. Proc Natl Acad Sci U S A. 1994 Jul 19; 91(15):7134-8. PMID: 8041759.
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    48. Speed TP, McPeek MS, Evans SN. Robustness of the no-interference model for ordering genetic markers. Proc Natl Acad Sci U S A. 1992 Apr 01; 89(7):3103-6. PMID: 1557418.
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    49. Guerra R, McPeek MS, Speed TP, Stewart PM. A Bayesian analysis for mapping from radiation hybrid data. Cytogenet Cell Genet. 1992; 59(2-3):104-6. PMID: 1737469.
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