"Blood-Brain Barrier" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specialized non-fenestrated tightly-joined ENDOTHELIAL CELLS with TIGHT JUNCTIONS that form a transport barrier for certain substances between the cerebral capillaries and the BRAIN tissue.
| Descriptor ID |
D001812
|
| MeSH Number(s) |
A07.035 A08.186.211.035
|
| Concept/Terms |
Blood-Brain Barrier- Blood-Brain Barrier
- Barrier, Blood-Brain
- Barriers, Blood-Brain
- Blood Brain Barrier
- Blood-Brain Barriers
- Hemato-Encephalic Barrier
- Barrier, Hemato-Encephalic
- Barriers, Hemato-Encephalic
- Hemato Encephalic Barrier
- Hemato-Encephalic Barriers
- Brain-Blood Barrier
- Barrier, Brain-Blood
- Barriers, Brain-Blood
- Brain Blood Barrier
- Brain-Blood Barriers
|
Below are MeSH descriptors whose meaning is more general than "Blood-Brain Barrier".
Below are MeSH descriptors whose meaning is more specific than "Blood-Brain Barrier".
This graph shows the total number of publications written about "Blood-Brain Barrier" by people in this website by year, and whether "Blood-Brain Barrier" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 |
| 1994 | 2 | 0 | 2 |
| 1999 | 1 | 1 | 2 |
| 2001 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2007 | 2 | 1 | 3 |
| 2008 | 0 | 1 | 1 |
| 2009 | 2 | 2 | 4 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 2 | 3 |
| 2012 | 0 | 1 | 1 |
| 2014 | 3 | 1 | 4 |
| 2015 | 2 | 0 | 2 |
| 2016 | 1 | 2 | 3 |
| 2017 | 2 | 2 | 4 |
| 2018 | 1 | 1 | 2 |
| 2020 | 0 | 1 | 1 |
| 2021 | 3 | 0 | 3 |
| 2022 | 1 | 1 | 2 |
| 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Blood-Brain Barrier" by people in Profiles.
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Clostridium epsilon toxin is excessive in multiple sclerosis and provokes multifocal lesions in mouse models. J Clin Invest. 2023 05 01; 133(9).
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Limosilactobacillus reuteri normalizes blood-brain barrier dysfunction and neurodevelopment deficits associated with prenatal exposure to lipopolysaccharide. Gut Microbes. 2023 Jan-Dec; 15(1):2178800.
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Increased Type I interferon signaling and brain endothelial barrier dysfunction in an experimental model of Alzheimer's disease. Sci Rep. 2022 10 01; 12(1):16488.
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Computational Assessment of Different Structural Models for Claudin-5 Complexes in Blood-Brain Barrier Tight Junctions. ACS Chem Neurosci. 2022 07 20; 13(14):2140-2153.
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Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug. Cell Rep. 2021 11 02; 37(5):109957.
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Structural basis of omega-3 fatty acid transport across the blood-brain barrier. Nature. 2021 07; 595(7866):315-319.
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Increase in Blood-Brain Barrier (BBB) Permeability Is Regulated by MMP3 via the ERK Signaling Pathway. Oxid Med Cell Longev. 2021; 2021:6655122.
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Regulator of G-Protein Signaling 5 Maintains Brain Endothelial Cell Function in Focal Cerebral Ischemia. J Am Heart Assoc. 2020 09 15; 9(18):e017533.
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Claudin-1-Dependent Destabilization of the Blood-Brain Barrier in Chronic Stroke. J Neurosci. 2019 01 23; 39(4):743-757.
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Leukaemia hijacks a neural mechanism to invade the central nervous system. Nature. 2018 08; 560(7716):55-60.