 Genes, Homeobox
"Genes, Homeobox" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes that encode highly conserved TRANSCRIPTION FACTORS that control positional identity of cells (BODY PATTERNING) and MORPHOGENESIS throughout development. Their sequences contain a 180 nucleotide sequence designated the homeobox, so called because mutations of these genes often results in homeotic transformations, in which one body structure replaces another. The proteins encoded by homeobox genes are called HOMEODOMAIN PROTEINS.
| Descriptor ID |
D005801
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| MeSH Number(s) |
G05.360.340.024.340.230.500
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| Concept/Terms |
Genes, Homeobox- Genes, Homeobox
- Gene, Homeobox
- Homeobox Gene
- Homeobox Genes
- Homeotic Genes
- Genes, Homeo Box
- Gene, Homeo Box
- Homeo Box Gene
- Homeo Box Genes
- Genes, Homeotic
- Gene, Homeotic
- Homeotic Gene
Homeo Box Sequence- Homeo Box Sequence
- Homeo Box Sequences
- Sequences, Homeo Box
- Homeo Boxes
- Homeobox
- Homeobox Sequence
- Homeobox Sequences
- Sequence, Homeobox
- Sequences, Homeobox
- Sequence, Homeo Box
- Homeo Box
- Homeoboxes
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Below are MeSH descriptors whose meaning is more general than "Genes, Homeobox".
Below are MeSH descriptors whose meaning is more specific than "Genes, Homeobox".
This graph shows the total number of publications written about "Genes, Homeobox" by people in this website by year, and whether "Genes, Homeobox" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1987 | 2 | 1 | 3 | | 1988 | 2 | 0 | 2 | | 1989 | 1 | 0 | 1 | | 1990 | 2 | 0 | 2 | | 1991 | 3 | 0 | 3 | | 1993 | 1 | 0 | 1 | | 1994 | 2 | 2 | 4 | | 1995 | 3 | 0 | 3 | | 1996 | 1 | 1 | 2 | | 1997 | 0 | 1 | 1 | | 1998 | 5 | 3 | 8 | | 1999 | 1 | 0 | 1 | | 2000 | 1 | 0 | 1 | | 2001 | 0 | 2 | 2 | | 2002 | 2 | 3 | 5 | | 2003 | 2 | 1 | 3 | | 2004 | 4 | 0 | 4 | | 2005 | 3 | 0 | 3 | | 2006 | 1 | 0 | 1 | | 2007 | 1 | 1 | 2 | | 2009 | 1 | 1 | 2 | | 2010 | 2 | 0 | 2 | | 2011 | 1 | 0 | 1 | | 2012 | 0 | 3 | 3 | | 2013 | 1 | 2 | 3 | | 2014 | 0 | 1 | 1 | | 2015 | 2 | 2 | 4 | | 2016 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Genes, Homeobox" by people in Profiles.
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Bickelmann C, Frota-Lima GN, Triepel SK, Kawaguchi A, Schneider I, Fröbisch NB. Noncanonical Hox, Etv4, and Gli3 gene activities give insight into unique limb patterning in salamanders. J Exp Zool B Mol Dev Evol. 2018 05; 330(3):138-147.
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Chang J, Skromne I, Ho RK. CDX4 and retinoic acid interact to position the hindbrain-spinal cord transition. Dev Biol. 2016 Feb 15; 410(2):178-189.
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Martin A, Serano JM, Jarvis E, Bruce HS, Wang J, Ray S, Barker CA, O'Connell LC, Patel NH. CRISPR/Cas9 Mutagenesis Reveals Versatile Roles of Hox Genes in Crustacean Limb Specification and Evolution. Curr Biol. 2016 Jan 11; 26(1):14-26.
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Hayward AG, Joshi P, Skromne I. Spatiotemporal analysis of zebrafish hox gene regulation by Cdx4. Dev Dyn. 2015 Dec; 244(12):1564-73.
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Gómez-Marín C, Tena JJ, Acemel RD, López-Mayorga M, Naranjo S, de la Calle-Mustienes E, Maeso I, Beccari L, Aneas I, Vielmas E, Bovolenta P, Nobrega MA, Carvajal J, Gómez-Skarmeta JL. Evolutionary comparison reveals that diverging CTCF sites are signatures of ancestral topological associating domains borders. Proc Natl Acad Sci U S A. 2015 Jun 16; 112(24):7542-7.
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Huang J, Zhang H, Wang X, Dobbs KB, Yao J, Qin G, Whitworth K, Walters EM, Prather RS, Zhao J. Impairment of preimplantation porcine embryo development by histone demethylase KDM5B knockdown through disturbance of bivalent H3K4me3-H3K27me3 modifications. Biol Reprod. 2015 Mar; 92(3):72.
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Gehrke AR, Schneider I, de la Calle-Mustienes E, Tena JJ, Gomez-Marin C, Chandran M, Nakamura T, Braasch I, Postlethwait JH, Gómez-Skarmeta JL, Shubin NH. Deep conservation of wrist and digit enhancers in fish. Proc Natl Acad Sci U S A. 2015 Jan 20; 112(3):803-8.
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Andrey G, Montavon T, Mascrez B, Gonzalez F, Noordermeer D, Leleu M, Trono D, Spitz F, Duboule D. A switch between topological domains underlies HoxD genes collinearity in mouse limbs. Science. 2013 Jun 07; 340(6137):1234167.
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Amemiya CT, Alföldi J, Lee AP, Fan S, Philippe H, Maccallum I, Braasch I, Manousaki T, Schneider I, Rohner N, Organ C, Chalopin D, Smith JJ, Robinson M, Dorrington RA, Gerdol M, Aken B, Biscotti MA, Barucca M, Baurain D, Berlin AM, Blatch GL, Buonocore F, Burmester T, Campbell MS, Canapa A, Cannon JP, Christoffels A, De Moro G, Edkins AL, Fan L, Fausto AM, Feiner N, Forconi M, Gamieldien J, Gnerre S, Gnirke A, Goldstone JV, Haerty W, Hahn ME, Hesse U, Hoffmann S, Johnson J, Karchner SI, Kuraku S, Lara M, Levin JZ, Litman GW, Mauceli E, Miyake T, Mueller MG, Nelson DR, Nitsche A, Olmo E, Ota T, Pallavicini A, Panji S, Picone B, Ponting CP, Prohaska SJ, Przybylski D, Saha NR, Ravi V, Ribeiro FJ, Sauka-Spengler T, Scapigliati G, Searle SM, Sharpe T, Simakov O, Stadler PF, Stegeman JJ, Sumiyama K, Tabbaa D, Tafer H, Turner-Maier J, van Heusden P, White S, Williams L, Yandell M, Brinkmann H, Volff JN, Tabin CJ, Shubin N, Schartl M, Jaffe DB, Postlethwait JH, Venkatesh B, Di Palma F, Lander ES, Meyer A, Lindblad-Toh K. The African coelacanth genome provides insights into tetrapod evolution. Nature. 2013 Apr 18; 496(7445):311-6.
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Schneider I, Shubin NH. The origin of the tetrapod limb: from expeditions to enhancers. Trends Genet. 2013 Jul; 29(7):419-26.
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