Dapsone
"Dapsone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sulfone active against a wide range of bacteria but mainly employed for its actions against MYCOBACTERIUM LEPRAE. Its mechanism of action is probably similar to that of the SULFONAMIDES which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with PYRIMETHAMINE in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8)
Descriptor ID |
D003622
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MeSH Number(s) |
D02.886.590.263
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Concept/Terms |
Dapsone- Dapsone
- Sulfonyldianiline
- Diaminodiphenylsulfone
- Diaphenylsulfone
- 4,4'-Diaminophenyl Sulfone
- 4,4' Diaminophenyl Sulfone
- Sulfone, 4,4'-Diaminophenyl
- DADPS
Sulfona- Sulfona
- Orsade Brand of Dapsone
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Below are MeSH descriptors whose meaning is more general than "Dapsone".
Below are MeSH descriptors whose meaning is more specific than "Dapsone".
This graph shows the total number of publications written about "Dapsone" by people in this website by year, and whether "Dapsone" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1982 | 1 | 0 | 1 | 1984 | 1 | 0 | 1 | 1995 | 0 | 1 | 1 | 1999 | 1 | 0 | 1 | 2004 | 0 | 1 | 1 | 2006 | 1 | 0 | 1 | 2007 | 1 | 0 | 1 | 2011 | 1 | 1 | 2 |
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Below are the most recent publications written about "Dapsone" by people in Profiles.
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Bolotin D, Petronic-Rosic V, Shea CR. Cutaneous Churg-Strauss syndrome: response to dapsone therapy. J Am Acad Dermatol. 2011 Jul; 65(1):244-6.
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Bolotin D, Petronic-Rosic V. Dermatitis herpetiformis. Part II. Diagnosis, management, and prognosis. J Am Acad Dermatol. 2011 Jun; 64(6):1027-33; quiz 1033-4.
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Zosel A, Rychter K, Leikin JB. Dapsone-induced methemoglobinemia: case report and literature review. Am J Ther. 2007 Nov-Dec; 14(6):585-7.
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Hoffman LD, Hoffman MD. Dapsone in the treatment of persistent erythema multiforme. J Drugs Dermatol. 2006 Apr; 5(4):375-6.
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Gluth MB, Witman PM, Thompson DM. Upper aerodigestive tract complications in a neonate with linear IgA bullous dermatosis. Int J Pediatr Otorhinolaryngol. 2004 Jul; 68(7):965-70.
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Mirochnick M, Cooper E, McIntosh K, Xu J, Lindsey J, Jacobus D, Mofenson L, Sullivan JL, Dankner W, Frenkel LM, Nachman S, Wara DW, Johnson D, Bonagura VR, Rathore MH, Cunningham CK, McNamara J. Pharmacokinetics of dapsone administered daily and weekly in human immunodeficiency virus-infected children. Antimicrob Agents Chemother. 1999 Nov; 43(11):2586-91.
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Maier H, Diem E, Gotschim A, Ortel B. [Pyoderma gangrenosum as a precursor of myeloid leukemia]. Hautarzt. 1995 Sep; 46(9):647-50.
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Glassroth J, Jordan M, Wallace JM, Kvale PA, Follmann DA, Rosen MJ, Reichman LB, Mossar M, Hopewell PC. Use of preventive interventions by persons infected with type-1 human immunodeficiency virus (HIV-1). The Pulmonary Complications of HIV Study Group. Am J Prev Med. 1994 Sep-Oct; 10(5):259-66.
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Rosenbaum MM, Esterly NB, Greenwald MJ, Gerson CR. Cicatricial pemphigoid in a 6-year-old child: report of a case and review of the literature. Pediatr Dermatol. 1984 Jul; 2(1):13-22.
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Hall RP, Lawley TJ, Smith HR, Katz SI. Bullous eruption of systemic lupus erythematosus. Dramatic response to dapsone therapy. Ann Intern Med. 1982 Aug; 97(2):165-70.
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