 Imidazoles
"Imidazoles" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds containing 1,3-diazole, a five membered aromatic ring containing two nitrogen atoms separated by one of the carbons. Chemically reduced ones include IMIDAZOLINES and IMIDAZOLIDINES. Distinguish from 1,2-diazole (PYRAZOLES).
| Descriptor ID |
D007093
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| MeSH Number(s) |
D03.383.129.308
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Imidazoles".
Below are MeSH descriptors whose meaning is more specific than "Imidazoles".
This graph shows the total number of publications written about "Imidazoles" by people in this website by year, and whether "Imidazoles" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1983 | 1 | 0 | 1 | | 1984 | 2 | 0 | 2 | | 1985 | 2 | 0 | 2 | | 1986 | 2 | 0 | 2 | | 1987 | 0 | 2 | 2 | | 1990 | 0 | 1 | 1 | | 1991 | 1 | 0 | 1 | | 1992 | 1 | 0 | 1 | | 1993 | 0 | 1 | 1 | | 1994 | 0 | 3 | 3 | | 1995 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 1999 | 1 | 2 | 3 | | 2001 | 2 | 3 | 5 | | 2002 | 2 | 0 | 2 | | 2003 | 1 | 0 | 1 | | 2004 | 1 | 3 | 4 | | 2005 | 3 | 3 | 6 | | 2006 | 2 | 1 | 3 | | 2007 | 3 | 1 | 4 | | 2008 | 4 | 1 | 5 | | 2009 | 3 | 1 | 4 | | 2010 | 1 | 4 | 5 | | 2011 | 6 | 3 | 9 | | 2012 | 3 | 6 | 9 | | 2013 | 2 | 4 | 6 | | 2014 | 11 | 5 | 16 | | 2015 | 3 | 1 | 4 | | 2016 | 5 | 2 | 7 | | 2017 | 3 | 3 | 6 | | 2018 | 4 | 2 | 6 | | 2019 | 3 | 2 | 5 | | 2020 | 1 | 1 | 2 | | 2021 | 2 | 0 | 2 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Imidazoles" by people in Profiles.
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Perea-Gil I, Seeger T, Bruyneel AAN, Termglinchan V, Monte E, Lim EW, Vadgama N, Furihata T, Gavidia AA, Arthur Ataam J, Bharucha N, Martinez-Amador N, Ameen M, Nair P, Serrano R, Kaur B, Feyen DAM, Diecke S, Snyder MP, Metallo CM, Mercola M, Karakikes I. Serine biosynthesis as a novel therapeutic target for dilated cardiomyopathy. Eur Heart J. 2022 09 21; 43(36):3477-3489.
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Coukos JS, Moellering RE. Methylglyoxal Forms Diverse Mercaptomethylimidazole Crosslinks with Thiol and Guanidine Pairs in Endogenous Metabolites and Proteins. ACS Chem Biol. 2021 11 19; 16(11):2453-2461.
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Watts NB, Binkley N, Owens CD, Al-Hendy A, Puscheck EE, Shebley M, Schlaff WD, Simon JA. Bone Mineral Density Changes Associated With Pregnancy, Lactation, and Medical Treatments in Premenopausal Women and Effects Later in Life. J Womens Health (Larchmt). 2021 10; 30(10):1416-1430.
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Wang J, Prinz RA, Liu X, Xu X. In Vitro and In Vivo Antiviral Activity of Gingerenone A on Influenza A Virus Is Mediated by Targeting Janus Kinase 2. Viruses. 2020 10 08; 12(10).
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Rinella ME, Noureddin M. STELLAR 3 and STELLAR 4: Lessons from the fall of Icarus. J Hepatol. 2020 07; 73(1):9-11.
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Cavallone LF, Montana MC, Frey K, Kallogjeri D, Wages JM, Rodebaugh TL, Doshi T, Kharasch ED, Gereau RW. The metabotropic glutamate receptor 5 negative allosteric modulator fenobam: pharmacokinetics, side effects, and analgesic effects in healthy human subjects. Pain. 2020 01; 161(1):135-146.
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Hargrave DR, Bouffet E, Tabori U, Broniscer A, Cohen KJ, Hansford JR, Geoerger B, Hingorani P, Dunkel IJ, Russo MW, Tseng L, Dasgupta K, Gasal E, Whitlock JA, Kieran MW. Efficacy and Safety of Dabrafenib in Pediatric Patients with BRAF V600 Mutation-Positive Relapsed or Refractory Low-Grade Glioma: Results from a Phase I/IIa Study. Clin Cancer Res. 2019 12 15; 25(24):7303-7311.
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Lehmann BD, Abramson VG, Sanders ME, Mayer EL, Haddad TC, Nanda R, Van Poznak C, Storniolo AM, Nangia JR, Gonzalez-Ericsson PI, Sanchez V, Johnson KN, Abramson RG, Chen SC, Shyr Y, Arteaga CL, Wolff AC, Pietenpol JA. TBCRC 032 IB/II Multicenter Study: Molecular Insights to AR Antagonist and PI3K Inhibitor Efficacy in Patients with AR+ Metastatic Triple-Negative Breast Cancer. Clin Cancer Res. 2020 05 01; 26(9):2111-2123.
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Pedrosa M, Seyedkazemi S, Francque S, Sanyal A, Rinella M, Charlton M, Loomba R, Ratziu V, Kochuparampil J, Fischer L, Vaidyanathan S, Anstee QM. A randomized, double-blind, multicenter, phase 2b study to evaluate the safety and efficacy of a combination of tropifexor and cenicriviroc in patients with nonalcoholic steatohepatitis and liver fibrosis: Study design of the TANDEM trial. Contemp Clin Trials. 2020 01; 88:105889.
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Suh D, Jo S, Jiang W, Chipot C, Roux B. String Method for Protein-Protein Binding Free-Energy Calculations. J Chem Theory Comput. 2019 Nov 12; 15(11):5829-5844.
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