 Endoplasmic Reticulum
"Endoplasmic Reticulum" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A system of cisternae in the CYTOPLASM of many cells. In places the endoplasmic reticulum is continuous with the plasma membrane (CELL MEMBRANE) or outer membrane of the nuclear envelope. If the outer surfaces of the endoplasmic reticulum membranes are coated with ribosomes, the endoplasmic reticulum is said to be rough-surfaced (ENDOPLASMIC RETICULUM, ROUGH); otherwise it is said to be smooth-surfaced (ENDOPLASMIC RETICULUM, SMOOTH). (King & Stansfield, A Dictionary of Genetics, 4th ed)
| Descriptor ID |
D004721
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| MeSH Number(s) |
A11.284.430.214.190.875.248
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Endoplasmic Reticulum".
Below are MeSH descriptors whose meaning is more specific than "Endoplasmic Reticulum".
This graph shows the total number of publications written about "Endoplasmic Reticulum" by people in this website by year, and whether "Endoplasmic Reticulum" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 1 | 1 | | 1984 | 1 | 0 | 1 | | 1985 | 0 | 2 | 2 | | 1986 | 0 | 1 | 1 | | 1988 | 0 | 1 | 1 | | 1989 | 1 | 0 | 1 | | 1991 | 0 | 3 | 3 | | 1993 | 1 | 2 | 3 | | 1994 | 2 | 2 | 4 | | 1995 | 1 | 2 | 3 | | 1996 | 0 | 2 | 2 | | 1997 | 0 | 4 | 4 | | 1998 | 1 | 2 | 3 | | 1999 | 3 | 0 | 3 | | 2000 | 2 | 8 | 10 | | 2001 | 2 | 1 | 3 | | 2002 | 4 | 3 | 7 | | 2003 | 5 | 4 | 9 | | 2004 | 5 | 8 | 13 | | 2005 | 2 | 5 | 7 | | 2006 | 3 | 9 | 12 | | 2007 | 6 | 2 | 8 | | 2008 | 5 | 4 | 9 | | 2009 | 4 | 6 | 10 | | 2010 | 5 | 5 | 10 | | 2011 | 2 | 11 | 13 | | 2012 | 4 | 3 | 7 | | 2013 | 4 | 5 | 9 | | 2014 | 4 | 4 | 8 | | 2015 | 0 | 2 | 2 | | 2016 | 2 | 2 | 4 | | 2017 | 3 | 5 | 8 | | 2018 | 1 | 4 | 5 | | 2019 | 2 | 2 | 4 | | 2020 | 4 | 3 | 7 | | 2021 | 2 | 4 | 6 | | 2022 | 1 | 1 | 2 |
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Below are the most recent publications written about "Endoplasmic Reticulum" by people in Profiles.
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Sundaram A, Yamsek M, Zhong F, Hooda Y, Hegde RS, Keenan RJ. Substrate-driven assembly of a translocon for multipass membrane proteins. Nature. 2022 11; 611(7934):167-172.
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Smalinskaite L, Kim MK, Lewis AJO, Keenan RJ, Hegde RS. Mechanism of an intramembrane chaperone for multipass membrane proteins. Nature. 2022 11; 611(7934):161-166.
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Wei J, Harada BT, Lu D, Ma R, Gao B, Xu Y, Montauti E, Mani N, Chaudhuri SM, Gregory S, Weinberg SE, Zhang DD, Green R, He C, Fang D. HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver disease. Mol Cell. 2021 12 16; 81(24):5052-5065.e6.
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Hegde RS, Keenan RJ. The mechanisms of integral membrane protein biogenesis. Nat Rev Mol Cell Biol. 2022 02; 23(2):107-124.
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Govind AP, Jeyifous O, Russell TA, Yi Z, Weigel AV, Ramaprasad A, Newell L, Ramos W, Valbuena FM, Casler JC, Yan JZ, Glick BS, Swanson GT, Lippincott-Schwartz J, Green WN. Activity-dependent Golgi satellite formation in dendrites reshapes the neuronal surface glycoproteome. Elife. 2021 09 21; 10.
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Pan M, Yu Y, Ai H, Zheng Q, Xie Y, Liu L, Zhao M. Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nat Struct Mol Biol. 2021 07; 28(7):614-625.
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Dieterich IA, Cui Y, Braun MM, Lawton AJ, Robinson NH, Peotter JL, Yu Q, Casler JC, Glick BS, Audhya A, Denu JM, Li L, Puglielli L. Acetyl-CoA flux from the cytosol to the ER regulates engagement and quality of the secretory pathway. Sci Rep. 2021 01 21; 11(1):2013.
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Feder ZA, Ali A, Singh A, Krakowiak J, Zheng X, Bindokas VP, Wolfgeher D, Kron SJ, Pincus D. Subcellular localization of the J-protein Sis1 regulates the heat shock response. J Cell Biol. 2021 01 04; 220(1).
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Casler JC, Zajac AL, Valbuena FM, Sparvoli D, Jeyifous O, Turkewitz AP, Horne-Badovinac S, Green WN, Glick BS. ESCargo: a regulatable fluorescent secretory cargo for diverse model organisms. Mol Biol Cell. 2020 12 15; 31(26):2892-2903.
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Didonna A, Damotte V, Shams H, Matsunaga A, Caillier SJ, Dandekar R, Misra MK, Mofrad MRK, Oksenberg JR, Hollenbach JA. A splice acceptor variant in HLA-DRA affects the conformation and cellular localization of the class II DR alpha-chain. Immunology. 2021 02; 162(2):194-207.
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