 Clonidine
"Clonidine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
| Descriptor ID |
D003000
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| MeSH Number(s) |
D03.383.129.308.436.500
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| Concept/Terms |
Clonidine Hydrochloride- Clonidine Hydrochloride
- Hydrochloride, Clonidine
- Clonidine Monohydrochloride
- Monohydrochloride, Clonidine
Dixarit- Dixarit
- Boehringer Ingelheim Brand of Clonidine Hydrochloride
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Below are MeSH descriptors whose meaning is more general than "Clonidine".
Below are MeSH descriptors whose meaning is more specific than "Clonidine".
This graph shows the total number of publications written about "Clonidine" by people in this website by year, and whether "Clonidine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 0 | 1 | 1 | | 1982 | 2 | 1 | 3 | | 1983 | 1 | 0 | 1 | | 1985 | 2 | 0 | 2 | | 1986 | 1 | 2 | 3 | | 1987 | 2 | 1 | 3 | | 1988 | 1 | 0 | 1 | | 1989 | 3 | 0 | 3 | | 1990 | 4 | 0 | 4 | | 1991 | 2 | 0 | 2 | | 1992 | 1 | 0 | 1 | | 1993 | 1 | 0 | 1 | | 1994 | 2 | 0 | 2 | | 1996 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2009 | 1 | 1 | 2 | | 2010 | 1 | 0 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2015 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Clonidine" by people in Profiles.
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Hyoju SK, Zaborina O, van Goor H. SARS-CoV-2 and the sympathetic immune response: Dampening inflammation with antihypertensive drugs (Clonidine and Propranolol). Med Hypotheses. 2020 Nov; 144:110039.
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Lee RJ, Fanning JR, Coccaro EF. GH response to intravenous clonidine challenge correlates with history of childhood trauma in personality disorder. J Psychiatr Res. 2016 May; 76:38-43.
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Kornfield R, Watson S, Higashi AS, Conti RM, Dusetzina SB, Garfield CF, Dorsey ER, Huskamp HA, Alexander GC. Effects of FDA advisories on the pharmacologic treatment of ADHD, 2004-2008. Psychiatr Serv. 2013 Apr 01; 64(4):339-46.
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Patil SK, Anitescu M. Opioid-free perioperative analgesia for hemicolectomy in a patient with opioid-induced delirium: a case report and review of the analgesic efficacy of the alpha-2 agonist agents. Pain Pract. 2012 Nov; 12(8):656-62.
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Coccaro EF, Kavoussi RJ. GH response to intravenous clonidine challenge: absence of relationship with behavioral irritability, aggression, or impulsivity in human subjects. Psychiatry Res. 2010 Jul 30; 178(2):443-5.
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Leikin JB, Mackendrick WP, Maloney GE, Rhee JW, Farrell E, Wahl M, Kelly K. Use of clonidine in the prevention and management of neonatal abstinence syndrome. Clin Toxicol (Phila). 2009 Jul; 47(6):551-5.
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Musch MW, Arvans DL, Paris H, Chang EB. Alpha2-adrenergic receptors attenuate secretagogue-induced endocytosis and promote exocytosis of intestinal NHE2 and NHE3. J Pharmacol Exp Ther. 2009 Sep; 330(3):818-25.
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Horowitz R, Mazor SS, Aks SE, Leikin JB. Accidental clonidine patch ingestion in a child. Am J Ther. 2005 May-Jun; 12(3):272-4.
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Edwards L, Fishman D, Horowitz P, Bourbon N, Kester M, Ernsberger P. The I1-imidazoline receptor in PC12 pheochromocytoma cells activates protein kinases C, extracellular signal-regulated kinase (ERK) and c-jun N-terminal kinase (JNK). J Neurochem. 2001 Dec; 79(5):931-40.
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Roche WJ, Nwofia C, Gittler M, Patel R, Yarkony G. Catecholamine-induced hypertension in lumbosacral paraplegia: five case reports. Arch Phys Med Rehabil. 2000 Feb; 81(2):222-5.
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