 Fluoxetine
"Fluoxetine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
| Descriptor ID |
D005473
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| MeSH Number(s) |
D02.092.831.280
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| Concept/Terms |
Fluoxetine- Fluoxetine
- N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine
- Fluoxetin
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Below are MeSH descriptors whose meaning is more general than "Fluoxetine".
Below are MeSH descriptors whose meaning is more specific than "Fluoxetine".
This graph shows the total number of publications written about "Fluoxetine" by people in this website by year, and whether "Fluoxetine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 0 | 1 | 1 | | 1990 | 1 | 0 | 1 | | 1992 | 1 | 0 | 1 | | 1994 | 1 | 0 | 1 | | 1996 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 1999 | 2 | 0 | 2 | | 2001 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 0 | 1 | 1 | | 2004 | 3 | 0 | 3 | | 2006 | 1 | 1 | 2 | | 2007 | 3 | 0 | 3 | | 2008 | 2 | 0 | 2 | | 2009 | 2 | 0 | 2 | | 2010 | 1 | 0 | 1 | | 2011 | 1 | 1 | 2 | | 2012 | 3 | 0 | 3 | | 2013 | 3 | 0 | 3 | | 2014 | 1 | 0 | 1 | | 2015 | 2 | 0 | 2 | | 2019 | 0 | 1 | 1 | | 2021 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Fluoxetine" by people in Profiles.
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Bi J, Khan A, Tang J, Armando AM, Wu S, Zhang W, Gimple RC, Reed A, Jing H, Koga T, Wong IT, Gu Y, Miki S, Yang H, Prager B, Curtis EJ, Wainwright DA, Furnari FB, Rich JN, Cloughesy TF, Kornblum HI, Quehenberger O, Rzhetsky A, Cravatt BF, Mischel PS. Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug. Cell Rep. 2021 11 02; 37(5):109957.
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Tunc-Ozcan E, Peng CY, Zhu Y, Dunlop SR, Contractor A, Kessler JA. Activating newborn neurons suppresses depression and anxiety-like behaviors. Nat Commun. 2019 08 21; 10(1):3768.
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Coccaro EF, Lee R, Breen EC, Irwin MR. Inflammatory markers and chronic exposure to fluoxetine, divalproex, and placebo in intermittent explosive disorder. Psychiatry Res. 2015 Oct 30; 229(3):844-9.
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Siddique J, Reiter JP, Brincks A, Gibbons RD, Crespi CM, Brown CH. Multiple imputation for harmonizing longitudinal non-commensurate measures in individual participant data meta-analysis. Stat Med. 2015 Nov 20; 34(26):3399-414.
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Zhu H, Grajales-Reyes GE, Alicea-Vázquez V, Grajales-Reyes JG, Robinson K, Pytel P, Báez-Pagán CA, Lasalde-Dominicci JA, Gomez CM. Fluoxetine is neuroprotective in slow-channel congenital myasthenic syndrome. Exp Neurol. 2015 Aug; 270:88-94.
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Woehrle NS, Klenotich SJ, Jamnia N, Ho EV, Dulawa SC. Effects of chronic fluoxetine treatment on serotonin 1B receptor-induced deficits in delayed alternation. Psychopharmacology (Berl). 2013 Jun; 227(3):545-51.
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Crow SJ, Agras WS, Halmi KA, Fairburn CG, Mitchell JE, Nyman JA. A cost effectiveness analysis of stepped care treatment for bulimia nervosa. Int J Eat Disord. 2013 May; 46(4):302-7.
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Gibbons RD, Brown CH, Hur K, Davis JM, Mann JJ. Inappropriate data and measures lead to questionable conclusions--reply. JAMA Psychiatry. 2013 Jan; 70(1):122-3.
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Gibbons RD, Brown CH, Hur K, Davis JM, Mann JJ. Suicide risk and efficacy of antidepressant drugs--reply. JAMA Psychiatry. 2013 Jan; 70(1):123-5.
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Gibbons RD, Brown CH, Hur K, Davis J, Mann JJ. Suicidal thoughts and behavior with antidepressant treatment: reanalysis of the randomized placebo-controlled studies of fluoxetine and venlafaxine. Arch Gen Psychiatry. 2012 Jun; 69(6):580-7.
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