"Megestrol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione. A progestational hormone used most commonly as the acetate ester. As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer.
| Descriptor ID |
D008535
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| MeSH Number(s) |
D04.210.500.745.432.531
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Megestrol".
Below are MeSH descriptors whose meaning is more specific than "Megestrol".
This graph shows the total number of publications written about "Megestrol" by people in this website by year, and whether "Megestrol" was a major or minor topic of these publications.
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Below are the most recent publications written about "Megestrol" by people in Profiles.
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Megestrol acetate reverses multidrug resistance and interacts with P-glycoprotein. Cancer Chemother Pharmacol. 1992; 29(6):445-9.
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Sequential hormone therapy for advanced breast cancer. Semin Oncol. 1988 Apr; 15(2 Suppl 1):38-43.
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Quantitative estrogen and progesterone receptor levels related to progression-free interval in advanced breast cancer patients treated with megestrol acetate or tamoxifen. Semin Oncol. 1988 Apr; 15(2 Suppl 1):26-33.
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Primary hormonal therapy of advanced breast cancer with megestrol acetate: predictive value of estrogen receptor and progesterone receptor levels. Semin Oncol. 1985 Mar; 12(1 Suppl 1):48-54.
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Comparative studies of the ethynyl estrogens used in oral contraceptives: effects with and without progestational agents on plasma cortisol and cortisol binding in humans, baboons, and beagles. Fertil Steril. 1977 Nov; 28(11):1182-90.