 Intercalating Agents
"Intercalating Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Agents that are capable of inserting themselves between the successive bases in DNA, thus kinking, uncoiling or otherwise deforming it and therefore preventing its proper functioning. They are used in the study of DNA.
| Descriptor ID |
D007364
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| MeSH Number(s) |
D27.720.470.410.360
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| Concept/Terms |
Intercalating Agents- Intercalating Agents
- Agents, Intercalating
- Intercalators
- Intercalative Compounds
- Compounds, Intercalative
- Intercalating Ligands
- Ligands, Intercalating
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Below are MeSH descriptors whose meaning is more general than "Intercalating Agents".
Below are MeSH descriptors whose meaning is more specific than "Intercalating Agents".
This graph shows the total number of publications written about "Intercalating Agents" by people in this website by year, and whether "Intercalating Agents" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1983 | 1 | 0 | 1 | | 1988 | 1 | 0 | 1 | | 1993 | 1 | 0 | 1 | | 1996 | 0 | 1 | 1 | | 1998 | 1 | 0 | 1 | | 2003 | 0 | 1 | 1 | | 2009 | 0 | 2 | 2 |
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Below are the most recent publications written about "Intercalating Agents" by people in Profiles.
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Lange Y, Ye J, Duban ME, Steck TL. Activation of membrane cholesterol by 63 amphipaths. Biochemistry. 2009 Sep 15; 48(36):8505-15.
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Lange Y, Steck TL, Ye J, Lanier MH, Molugu V, Ory D. Regulation of fibroblast mitochondrial 27-hydroxycholesterol production by active plasma membrane cholesterol. J Lipid Res. 2009 Sep; 50(9):1881-8.
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Bindokas VP, Kuznetsov A, Sreenan S, Polonsky KS, Roe MW, Philipson LH. Visualizing superoxide production in normal and diabetic rat islets of Langerhans. J Biol Chem. 2003 Mar 14; 278(11):9796-801.
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Bischoff G, Bischoff R, Birch-Hirschfeld E, Gromann U, Lindau S, Meister WV, de A Bambirra S, Bohley C, Hoffmann S. DNA-drug interaction measurements using surface plasmon resonance. J Biomol Struct Dyn. 1998 Oct; 16(2):187-203.
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Rice PA, Yang S, Mizuuchi K, Nash HA. Crystal structure of an IHF-DNA complex: a protein-induced DNA U-turn. Cell. 1996 Dec 27; 87(7):1295-306.
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Ratain MJ, Mick R, Berezin F, Janisch L, Schilsky RL, Vogelzang NJ, Lane LB. Phase I study of amonafide dosing based on acetylator phenotype. Cancer Res. 1993 May 15; 53(10 Suppl):2304-8.
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Ratain MJ, Staubus AE, Schilsky RL, Malspeis L. Limited sampling models for amonafide (NSC 308847) pharmacokinetics. Cancer Res. 1988 Jul 15; 48(14):4127-30.
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Gams RA, Keller JW, Golomb HM, Steinberg J, Dukart G. Mitoxantrone in malignant lymphomas. Cancer Treat Rev. 1983 Dec; 10 Suppl B:69-72.
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