 Extracellular Matrix
"Extracellular Matrix" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A meshwork-like substance found within the extracellular space and in association with the basement membrane of the cell surface. It promotes cellular proliferation and provides a supporting structure to which cells or cell lysates in culture dishes adhere.
| Descriptor ID |
D005109
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| MeSH Number(s) |
A11.284.295.310
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| Concept/Terms |
Extracellular Matrix- Extracellular Matrix
- Matrix, Extracellular
- Extracellular Matrices
- Matrices, Extracellular
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Below are MeSH descriptors whose meaning is more general than "Extracellular Matrix".
Below are MeSH descriptors whose meaning is more specific than "Extracellular Matrix".
This graph shows the total number of publications written about "Extracellular Matrix" by people in this website by year, and whether "Extracellular Matrix" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1987 | 0 | 1 | 1 | | 1988 | 2 | 0 | 2 | | 1989 | 0 | 1 | 1 | | 1990 | 1 | 0 | 1 | | 1991 | 0 | 2 | 2 | | 1992 | 1 | 0 | 1 | | 1993 | 0 | 2 | 2 | | 1994 | 1 | 1 | 2 | | 1996 | 2 | 2 | 4 | | 1997 | 2 | 2 | 4 | | 1998 | 1 | 2 | 3 | | 1999 | 2 | 1 | 3 | | 2000 | 1 | 2 | 3 | | 2001 | 2 | 2 | 4 | | 2002 | 1 | 2 | 3 | | 2003 | 2 | 5 | 7 | | 2004 | 2 | 3 | 5 | | 2005 | 4 | 6 | 10 | | 2006 | 6 | 3 | 9 | | 2007 | 6 | 3 | 9 | | 2008 | 2 | 6 | 8 | | 2009 | 5 | 5 | 10 | | 2010 | 3 | 3 | 6 | | 2011 | 7 | 8 | 15 | | 2012 | 1 | 5 | 6 | | 2013 | 6 | 8 | 14 | | 2014 | 3 | 8 | 11 | | 2015 | 6 | 2 | 8 | | 2016 | 1 | 6 | 7 | | 2017 | 2 | 2 | 4 | | 2018 | 1 | 5 | 6 | | 2019 | 5 | 3 | 8 | | 2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "Extracellular Matrix" by people in Profiles.
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Pimentel MB, Borges FTP, Teymour F, Zaborina OY, Alverdy JC, Fang K, Hong SH, Staneviciute A, He YJ, Papavasiliou G. An in vitro tissue model for screening sustained release of phosphate-based therapeutic attenuation of pathogen-induced proteolytic matrix degradation. J Mater Chem B. 2020 03 25; 8(12):2454-2465.
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Unlu G, Qi X, Gamazon ER, Melville DB, Patel N, Rushing AR, Hashem M, Al-Faifi A, Chen R, Li B, Cox NJ, Alkuraya FS, Knapik EW. Phenome-based approach identifies RIC1-linked Mendelian syndrome through zebrafish models, biobank associations and clinical studies. Nat Med. 2020 01; 26(1):98-109.
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Katsumata K, Ishihara J, Fukunaga K, Ishihara A, Yuba E, Budina E, Hubbell JA. Conferring extracellular matrix affinity enhances local therapeutic efficacy of anti-TNF-a antibody in a murine model of rheumatoid arthritis. Arthritis Res Ther. 2019 12 23; 21(1):298.
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Mochizuki M, Güç E, Park AJ, Julier Z, Briquez PS, Kuhn GA, Müller R, Swartz MA, Hubbell JA, Martino MM. Growth factors with enhanced syndecan binding generate tonic signalling and promote tissue healing. Nat Biomed Eng. 2020 04; 4(4):463-475.
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Hegab AE, Ozaki M, Kameyama N, Gao J, Kagawa S, Yasuda H, Soejima K, Yin Y, Guzy RD, Nakamura Y, Ornitz DM, Betsuyaku T. Effect of FGF/FGFR pathway blocking on lung adenocarcinoma and its cancer-associated fibroblasts. J Pathol. 2019 10; 249(2):193-205.
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Gomez-Stallons MV, Tretter JT, Hassel K, Gonzalez-Ramos O, Amofa D, Ollberding NJ, Mazur W, Choo JK, Smith JM, Kereiakes DJ, Yutzey KE. Calcification and extracellular matrix dysregulation in human postmortem and surgical aortic valves. Heart. 2019 11; 105(21):1616-1621.
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Parisien M, Samoshkin A, Tansley SN, Piltonen MH, Martin LJ, El-Hachem N, Dagostino C, Allegri M, Mogil JS, Khoutorsky A, Diatchenko L. Genetic pathway analysis reveals a major role for extracellular matrix organization in inflammatory and neuropathic pain. Pain. 2019 Apr; 160(4):932-944.
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Jezela-Stanek A, Walczak A, Lazniewski M, Kosinska J, Stawinski P, Murcia Pienkowski V, Biernacka A, Rydzanicz M, Kostrzewa G, Krajewski P, Plewczynski D, Ploski R. Novel COL12A1 variant as a cause of mild familial extracellular matrix-related myopathy. Clin Genet. 2019 06; 95(6):736-738.
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Zielinski MS, Vardar E, Vythilingam G, Engelhardt EM, Hubbell JA, Frey P, Larsson HM. Quantitative intrinsic auto-cathodoluminescence can resolve spectral signatures of tissue-isolated collagen extracellular matrix. Commun Biol. 2019; 2:69.
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Chen HJ, Shuler ML. Engineering a Bioartificial Human Colon Model Through Decellularization and Recellularization. Methods Mol Biol. 2019; 1907:91-102.
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