"Monoamine Oxidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the oxidative deamination of naturally occurring monoamines. It is a flavin-containing enzyme that is localized in mitochondrial membranes, whether in nerve terminals, the liver, or other organs. Monoamine oxidase is important in regulating the metabolic degradation of catecholamines and serotonin in neural or target tissues. Hepatic monoamine oxidase has a crucial defensive role in inactivating circulating monoamines or those, such as tyramine, that originate in the gut and are absorbed into the portal circulation. (From Goodman and Gilman's, The Pharmacological Basis of Therapeutics, 8th ed, p415) EC 1.4.3.4.
| Descriptor ID |
D008995
|
| MeSH Number(s) |
D08.811.682.664.750
|
| Concept/Terms |
Monoamine Oxidase- Monoamine Oxidase
- Oxidase, Monoamine
- Amine Oxidase (Flavin-Containing)
- MAO
- Tyramine Oxidase
- Oxidase, Tyramine
|
Below are MeSH descriptors whose meaning is more general than "Monoamine Oxidase".
Below are MeSH descriptors whose meaning is more specific than "Monoamine Oxidase".
This graph shows the total number of publications written about "Monoamine Oxidase" by people in this website by year, and whether "Monoamine Oxidase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2009 | 2 | 0 | 2 |
| 2010 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Monoamine Oxidase" by people in Profiles.
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Enhanced Catecholamine Flux and Impaired Carbonyl Metabolism Disrupt Cardiac Mitochondrial Oxidative Phosphorylation in Diabetes Patients. Antioxid Redox Signal. 2021 08 01; 35(4):235-251.
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Target Molecular-Based Neuroactivity Screening and Analysis of Panax ginseng by Affinity Ultrafiltration, UPLC-QTOF-MS and Molecular Docking. Am J Chin Med. 2019; 47(6):1345-1363.
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Pathway of Maternal Serotonin to the Human Embryo and Fetus. Endocrinology. 2018 04 01; 159(4):1609-1629.
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Does MAOA increase susceptibility to prenatal stress in young children? Neurotoxicol Teratol. 2017 05; 61:82-91.
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XM: association testing on the X-chromosome in case-control samples with related individuals. Genet Epidemiol. 2012 Jul; 36(5):438-50.
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The SNAG domain of Snail1 functions as a molecular hook for recruiting lysine-specific demethylase 1. EMBO J. 2010 Jun 02; 29(11):1803-16.
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Negative emotionality: monoamine oxidase B gene variants modulate personality traits in healthy humans. J Neural Transm (Vienna). 2009 Oct; 116(10):1323-34.
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Interaction of prenatal exposure to cigarettes and MAOA genotype in pathways to youth antisocial behavior. Mol Psychiatry. 2010 Sep; 15(9):928-37.
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Genetic tests of biologic systems in affective disorders. Mol Psychiatry. 2005 Aug; 10(8):719-40.
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Case-control study of dopamine transporter-1, monoamine oxidase-B, and catechol-O-methyl transferase polymorphisms in Parkinson's disease. Mov Disord. 2002 Nov; 17(6):1305-11.