 Methadone
"Methadone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
| Descriptor ID |
D008691
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| MeSH Number(s) |
D02.522.675
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| Concept/Terms |
Biodone- Biodone
- Biomet Brand of Methadone Hydrochloride
Dolophine- Dolophine
- Roxane Brand of Methadone Hydrochloride
Metadol- Metadol
- Pharmascience Brand of Methadone Hydrochloride
Metasedin- Metasedin
- Esteve Brand of Methadone Hydrochloride
Symoron- Symoron
- Yamanouchi Brand of Methadone Hydrochloride
Methadose- Methadose
- Rosemont Brand of Methadone Hydrochloride
- Mallinckrodt Brand of Methadone Hydrochloride
Methex- Methex
- Generics Brand of Methadone Hydrochloride
Physeptone- Physeptone
- Martindale Brand of Methadone Hydrochloride
- Phymet
- GlaxoSmithKline Brand of Methadone Hydrochloride
Pinadone- Pinadone
- Pinewood Brand of Methadone Hydrochloride
Methaddict- Methaddict
- addiCare Brand of Methadone Hydrochloride
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Below are MeSH descriptors whose meaning is more general than "Methadone".
Below are MeSH descriptors whose meaning is more specific than "Methadone".
This graph shows the total number of publications written about "Methadone" by people in this website by year, and whether "Methadone" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 1 | 0 | 1 | | 1996 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 1999 | 0 | 1 | 1 | | 2000 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2006 | 0 | 1 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2017 | 2 | 1 | 3 | | 2018 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 | | 2020 | 1 | 1 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Methadone" by people in Profiles.
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Avram MJ, Murphy GS, Szokol JW. Methadone and Chronic Pain: Reply. Anesthesiology. 2020 09; 133(3):672-673.
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Murphy GS, Avram MJ, Greenberg SB, Shear TD, Deshur MA, Dickerson D, Bilimoria S, Benson J, Maher CE, Trenk GJ, Teister KJ, Szokol JW. Postoperative Pain and Analgesic Requirements in the First Year after Intraoperative Methadone for Complex Spine and Cardiac Surgery. Anesthesiology. 2020 02; 132(2):330-342.
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Murphy GS, Szokol JW. Intraoperative Methadone in Surgical Patients: A Review of Clinical Investigations. Anesthesiology. 2019 09; 131(3):678-692.
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D'Aunno T, Park SE, Pollack HA. Evidence-based treatment for opioid use disorders: A national study of methadone dose levels, 2011-2017. J Subst Abuse Treat. 2019 01; 96:18-22.
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Klaman SL, Isaacs K, Leopold A, Perpich J, Hayashi S, Vender J, Campopiano M, Jones HE. Treating Women Who Are Pregnant and Parenting for Opioid Use Disorder and the Concurrent Care of Their Infants and Children: Literature Review to Support National Guidance. J Addict Med. 2017 May/Jun; 11(3):178-190.
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Murphy GS, Szokol JW, Avram MJ, Greenberg SB, Shear TD, Deshur MA, Vender JS, Benson J, Newmark RL. Clinical Effectiveness and Safety of Intraoperative Methadone in Patients Undergoing Posterior Spinal Fusion Surgery: A Randomized, Double-blinded, Controlled Trial. Anesthesiology. 2017 May; 126(5):822-833.
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Faul M, Bohm M, Alexander C. Methadone Prescribing and Overdose and the Association with Medicaid Preferred Drug List Policies - United States, 2007-2014. MMWR Morb Mortal Wkly Rep. 2017 Mar 31; 66(12):320-323.
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Murphy GS, Szokol JW, Avram MJ, Greenberg SB, Marymont JH, Shear T, Parikh KN, Patel SS, Gupta DK. Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients. Anesthesiology. 2015 May; 122(5):1112-22.
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D'Aunno T, Pollack HA, Frimpong JA, Wutchiett D. Evidence-based treatment for opioid disorders: a 23-year national study of methadone dose levels. J Subst Abuse Treat. 2014 10; 47(4):245-50.
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Matlock A, Allan N, Wills B, Kang C, Leikin JB. A continuing black hole? The FDA boxed warning: an appeal to improve its clinical utility. Clin Toxicol (Phila). 2011 Jul; 49(6):443-7.
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