 RNA, Transfer, Leu
"RNA, Transfer, Leu" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transfer RNA which is specific for carrying leucine to sites on the ribosomes in preparation for protein synthesis.
| Descriptor ID |
D012356
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| MeSH Number(s) |
D13.444.735.757.700.500
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| Concept/Terms |
RNA, Transfer, Leu- RNA, Transfer, Leu
- Transfer RNA, Leu
- Leu Transfer RNA
- RNA, Leu Transfer
- tRNA(Leu)
- tRNALeu
- Leucine-Specific tRNA
- Leucine Specific tRNA
- tRNA, Leucine-Specific
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Below are MeSH descriptors whose meaning is more general than "RNA, Transfer, Leu".
Below are MeSH descriptors whose meaning is more specific than "RNA, Transfer, Leu".
This graph shows the total number of publications written about "RNA, Transfer, Leu" by people in this website by year, and whether "RNA, Transfer, Leu" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1987 | 0 | 1 | 1 | | 1992 | 2 | 0 | 2 | | 1993 | 0 | 1 | 1 | | 1994 | 0 | 1 | 1 | | 1995 | 2 | 0 | 2 | | 1996 | 1 | 0 | 1 | | 2001 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "RNA, Transfer, Leu" by people in Profiles.
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Starck SR, Jiang V, Pavon-Eternod M, Prasad S, McCarthy B, Pan T, Shastri N. Leucine-tRNA initiates at CUG start codons for protein synthesis and presentation by MHC class I. Science. 2012 Jun 29; 336(6089):1719-23.
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Rawlings TA, Collins TM, Bieler R. Changing identities: tRNA duplication and remolding within animal mitochondrial genomes. Proc Natl Acad Sci U S A. 2003 Dec 23; 100(26):15700-5.
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Boirie Y, Short KR, Ahlman B, Charlton M, Nair KS. Tissue-specific regulation of mitochondrial and cytoplasmic protein synthesis rates by insulin. Diabetes. 2001 Dec; 50(12):2652-8.
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Velho G, Byrne MM, Clément K, Sturis J, Pueyo ME, Blanché H, Vionnet N, Fiet J, Passa P, Robert JJ, Polonsky KS, Froguel P. Clinical phenotypes, insulin secretion, and insulin sensitivity in kindreds with maternally inherited diabetes and deafness due to mitochondrial tRNALeu(UUR) gene mutation. Diabetes. 1996 Apr; 45(4):478-87.
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Iwasaki N, Ohgawara H, Nagahara H, Kawamura M, Bell GI, Omori Y. Characterization of Japanese families with early-onset type 2 (non-insulin dependent) diabetes mellitus and screening for mutations in the glucokinase and mitochondrial tRNA(Leu(UUR)) genes. Acta Diabetol. 1995 Mar; 32(1):17-22.
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Koga Y, Davidson M, Schon EA, King MP. Analysis of cybrids harboring MELAS mutations in the mitochondrial tRNA(Leu(UUR)) gene. Muscle Nerve Suppl. 1995; 3:S119-23.
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Vaxillaire M, Vionnet N, Vigouroux C, Sun F, Espinosa R, Lebeau MM, Stoffel M, Lehto M, Beckmann JS, Detheux M, et al. Search for a third susceptibility gene for maturity-onset diabetes of the young. Studies with eleven candidate genes. Diabetes. 1994 Mar; 43(3):389-95.
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Koga Y, Davidson M, Schon EA, King MP. Fine mapping of mitochondrial RNAs derived from the mtDNA region containing a point mutation associated with MELAS. Nucleic Acids Res. 1993 Feb 11; 21(3):657-62.
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Schon EA, Koga Y, Davidson M, Moraes CT, King MP. The mitochondrial tRNA(Leu)(UUR)) mutation in MELAS: a model for pathogenesis. Biochim Biophys Acta. 1992 Jul 17; 1101(2):206-9.
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King MP, Koga Y, Davidson M, Schon EA. Defects in mitochondrial protein synthesis and respiratory chain activity segregate with the tRNA(Leu(UUR)) mutation associated with mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes. Mol Cell Biol. 1992 Feb; 12(2):480-90.
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