An experimental animal model for the demyelinating disease of GUILLAINE-BARRE SYNDROME. In the most frequently used protocol, animals are injected with a peripheral nerve tissue protein homogenate. After approximately 2 weeks the animals develop a neuropathy secondary to a T cell-mediated autoimmune response directed towards the MYELIN P2 PROTEIN in peripheral nerves. Pathologic findings include a perivascular accumulation of macrophages and T lymphocytes in the peripheral nervous system, similar to that seen in the Guillaine-Barre syndrome. (From Adams et al., Principles of Neurology, 6th ed, p1314; J Neuroimmunol 1998 Apr 1;84(1):40-52)

Descriptor ID	D009444
MeSH Number(s)	C10.114.703.700 C10.668.829.650.500 C20.111.258.625.700 E05.598.500.500.875
Concept/Terms	Neuritis, Autoimmune, Experimental Neuritis, Autoimmune, Experimental Autoimmune Neuritis, Experimental EAN (Experimental Allergic Neuritis) Neuritis, Experimental Autoimmune Experimental Allergic Neuritis Experimental Autoimmune Neuritis Experimental Autoimmune Neuropathy Autoimmune Neuropathies, Experimental Autoimmune Neuropathy, Experimental Experimental Autoimmune Neuropathies Neuropathies, Experimental Autoimmune Neuropathy, Experimental Autoimmune Neuritis, Experimental Allergic Allergic Neuritis, Experimental EAN (Experimental Autoimmune Neuritis)

Below are MeSH descriptors whose meaning is more general than "Neuritis, Autoimmune, Experimental".

Below are MeSH descriptors whose meaning is related to "Neuritis, Autoimmune, Experimental".

Below are MeSH descriptors whose meaning is more specific than "Neuritis, Autoimmune, Experimental".