"Notochord" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cartilaginous rod of mesodermal cells at the dorsal midline of all CHORDATE embryos. In lower vertebrates, notochord is the backbone of support. In the higher vertebrates, notochord is a transient structure, and segments of the vertebral column will develop around it. Notochord is also a source of midline signals that pattern surrounding tissues including the NEURAL TUBE development.
| Descriptor ID |
D009672
|
| MeSH Number(s) |
A16.660
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Notochord".
Below are MeSH descriptors whose meaning is more specific than "Notochord".
This graph shows the total number of publications written about "Notochord" by people in this website by year, and whether "Notochord" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 0 | 2 |
| 1996 | 2 | 1 | 3 |
| 1998 | 1 | 0 | 1 |
| 2002 | 2 | 0 | 2 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 1 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Notochord" by people in Profiles.
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Ontogeny of the anuran urostyle and the developmental context of evolutionary novelty. Proc Natl Acad Sci U S A. 2020 02 11; 117(6):3034-3044.
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Embryonic origin of the gnathostome vertebral skeleton. Proc Biol Sci. 2017 Nov 29; 284(1867).
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Embryonic development of the axial column in the little skate, Leucoraja erinacea. J Morphol. 2017 03; 278(3):300-320.
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The 'Tully monster' is a vertebrate. Nature. 2016 Apr 28; 532(7600):496-9.
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FGF3 in the floor plate directs notochord convergent extension in the Ciona tadpole. Development. 2009 Jan; 136(1):23-8.
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Context dependent function of APPb enhancer identified using enhancer trap-containing BACs as transgenes in zebrafish. Nucleic Acids Res. 2008 Nov; 36(19):6237-48.
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Cellular morphogenesis in ascidians: how to shape a simple tadpole. Curr Opin Genet Dev. 2006 Aug; 16(4):399-405.
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Ascidian prickle regulates both mediolateral and anterior-posterior cell polarity of notochord cells. Curr Biol. 2005 Jan 11; 15(1):79-85.
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The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network. Mol Cell Biol. 2003 Jul; 23(13):4586-97.
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Polarized basolateral cell motility underlies invagination and convergent extension of the ascidian notochord. Development. 2002 Jan; 129(1):13-24.