"Fetal Hemoglobin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The major component of hemoglobin in the fetus. This HEMOGLOBIN has two alpha and two gamma polypeptide subunits in comparison to normal adult hemoglobin, which has two alpha and two beta polypeptide subunits. Fetal hemoglobin concentrations can be elevated (usually above 0.5%) in children and adults affected by LEUKEMIA and several types of ANEMIA.
Below are MeSH descriptors whose meaning is more general than "Fetal Hemoglobin".
Below are MeSH descriptors whose meaning is more specific than "Fetal Hemoglobin".
This graph shows the total number of publications written about "Fetal Hemoglobin" by people in this website by year, and whether "Fetal Hemoglobin" was a major or minor topic of these publications.
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Below are the most recent publications written about "Fetal Hemoglobin" by people in Profiles.
Impact of hydroxyurea dose and adherence on hematologic outcomes for children with sickle cell anemia. Pediatr Blood Cancer. 2022 06; 69(6):e29607.
Heterozygous variants in ZBTB7A cause a neurodevelopmental disorder associated with symptomatic overgrowth of pharyngeal lymphoid tissue, macrocephaly, and elevated fetal hemoglobin. Am J Med Genet A. 2022 01; 188(1):272-282.
Oral administration of the LSD1 inhibitor ORY-3001 increases fetal hemoglobin in sickle cell mice and baboons. Exp Hematol. 2018 11; 67:60-64.e2.
Potential role of LSD1 inhibitors in the treatment of sickle cell disease: a review of preclinical animal model data. Am J Physiol Regul Integr Comp Physiol. 2018 10 01; 315(4):R840-R847.
The LSD1 inhibitor RN-1 recapitulates the fetal pattern of hemoglobin synthesis in baboons (P. anubis). Haematologica. 2016 06; 101(6):688-97.
RN-1, a potent and selective lysine-specific demethylase 1 inhibitor, increases ?-globin expression, F reticulocytes, and F cells in a sickle cell disease mouse model. Exp Hematol. 2015 Jul; 43(7):546-53.e1-3.
A case of hereditary persistence of fetal hemoglobin caused by a gene not linked to the beta-globin cluster. Hum Genet. 1989 Jul; 82(4):335-7.
A further case of G gamma-beta + hereditary persistence of Hb F associated to the -202 C----G mutation in the G gamma promoter region. Hemoglobin. 1987; 11(4):389-93.
Anti-A1 in the plasma of platelet concentrates causing a hemolytic reaction. Transfusion. 1977 Jan-Feb; 17(1):29-32.
Significance of transplacental hemorrhage in the induction of specific maternal unresponsiveness. J Natl Cancer Inst. 1970 Nov; 45(5):997-1004.