 Immune Complex Diseases
"Immune Complex Diseases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Group of diseases mediated by the deposition of large soluble complexes of antigen and antibody with resultant damage to tissue. Besides SERUM SICKNESS and the ARTHUS REACTION, evidence supports a pathogenic role for immune complexes in many other IMMUNE SYSTEM DISEASES including GLOMERULONEPHRITIS, systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC) and POLYARTERITIS NODOSA.
| Descriptor ID |
D007105
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| MeSH Number(s) |
C20.543.520
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| Concept/Terms |
Immune Complex Diseases- Immune Complex Diseases
- Disease, Immune Complex
- Diseases, Immune Complex
- Immune Complex Disease
- Type III Hypersensitivity
- Hypersensitivity, Type III
- Hypersensitivities, Type III
- Type III Hypersensitivities
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Below are MeSH descriptors whose meaning is more general than "Immune Complex Diseases".
Below are MeSH descriptors whose meaning is more specific than "Immune Complex Diseases".
This graph shows the total number of publications written about "Immune Complex Diseases" by people in this website by year, and whether "Immune Complex Diseases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 0 | 1 | 1 | | 1982 | 1 | 1 | 2 | | 1998 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Immune Complex Diseases" by people in Profiles.
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Jacob A, Phelps M, Fraher S, Lopez M, Chang A, Quigg RJ, Alexander JJ. Macrophage Depletion Reduces Disease Pathology in Factor H-Dependent Immune Complex-Mediated Glomerulonephritis. J Immunol Res. 2022; 2022:1737419.
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Jacob A, Chaves L, Eadon MT, Chang A, Quigg RJ, Alexander JJ. Curcumin alleviates immune-complex-mediated glomerulonephritis in factor-H-deficient mice. Immunology. 2013 Jul; 139(3):328-37.
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Alexander JJ, Chaves L, Chang A, Quigg RJ. The C5a receptor has a key role in immune complex glomerulonephritis in complement factor H-deficient mice. Kidney Int. 2012 Nov; 82(9):961-8.
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Khan SN, Cox JV, Nishimoto SK, Chen C, Fritzler MJ, Hendershot LM, Weigert M, Radic M. Intra-Golgi formation of IgM-glycosaminoglycan complexes promotes Ig deposition. J Immunol. 2011 Sep 15; 187(6):3198-207.
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Alexander JJ, Hack BK, Jacob A, Chang A, Haas M, Finberg RW, Quigg RJ. Abnormal immune complex processing and spontaneous glomerulonephritis in complement factor H-deficient mice with human complement receptor 1 on erythrocytes. J Immunol. 2010 Sep 15; 185(6):3759-67.
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Alexander JJ, Aneziokoro OG, Chang A, Hack BK, Markaryan A, Jacob A, Luo R, Thirman M, Haas M, Quigg RJ. Distinct and separable roles of the complement system in factor H-deficient bone marrow chimeric mice with immune complex disease. J Am Soc Nephrol. 2006 May; 17(5):1354-61.
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Longerich S, Storb U. The contested role of uracil DNA glycosylase in immunoglobulin gene diversification. Trends Genet. 2005 May; 21(5):253-6.
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Sardani Y, Qin K, Haas M, Aronson AJ, Rosenfield RL. Bartter syndrome complicated by immune complex nephropathy. Case report and literature review. Pediatr Nephrol. 2003 Sep; 18(9):913-8.
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Tandin A, Miki T, Metes D, Lee Y, Kovscek AM, Subbotin V, Fung JJ, Valdivia LA. Immune complex disease in immunosuppressed rat recipients of hamster liver xenografts. Transplant Proc. 2001 Feb-Mar; 33(1-2):778.
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Quigg RJ, Lim A, Haas M, Alexander JJ, He C, Carroll MC. Immune complex glomerulonephritis in C4- and C3-deficient mice. Kidney Int. 1998 Feb; 53(2):320-30.
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