"Sarcoma, Kaposi" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multicentric, malignant neoplastic vascular proliferation characterized by the development of bluish-red cutaneous nodules, usually on the lower extremities, most often on the toes or feet, and slowly increasing in size and number and spreading to more proximal areas. The tumors have endothelium-lined channels and vascular spaces admixed with variably sized aggregates of spindle-shaped cells, and often remain confined to the skin and subcutaneous tissue, but widespread visceral involvement may occur. Kaposi's sarcoma occurs spontaneously in Jewish and Italian males in Europe and the United States. An aggressive variant in young children is endemic in some areas of Africa. A third form occurs in about 0.04% of kidney transplant patients. There is also a high incidence in AIDS patients. (From Dorland, 27th ed & Holland et al., Cancer Medicine, 3d ed, pp2105-7) HHV-8 is the suspected cause.
| Descriptor ID |
D012514
|
| MeSH Number(s) |
C02.256.466.860 C04.557.450.795.850 C04.557.645.750
|
| Concept/Terms |
Sarcoma, Kaposi- Sarcoma, Kaposi
- Kaposi's Sarcoma
- Kaposis Sarcoma
- Sarcoma, Kaposi's
- Multiple Idiopathic Pigmented Hemangiosarcoma
- Kaposi Sarcoma
|
Below are MeSH descriptors whose meaning is more general than "Sarcoma, Kaposi".
Below are MeSH descriptors whose meaning is more specific than "Sarcoma, Kaposi".
This graph shows the total number of publications written about "Sarcoma, Kaposi" by people in this website by year, and whether "Sarcoma, Kaposi" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 1 | 2 | 3 |
| 2002 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sarcoma, Kaposi" by people in Profiles.
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Nonsense-mediated decay controls the reactivation of the oncogenic herpesviruses EBV and KSHV. PLoS Biol. 2021 02; 19(2):e3001097.
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KSHV G-protein coupled receptor vGPCR oncogenic signaling upregulation of Cyclooxygenase-2 expression mediates angiogenesis and tumorigenesis in Kaposi's sarcoma. PLoS Pathog. 2020 10; 16(10):e1009006.
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Oral Kaposi Sarcoma. JAMA Dermatol. 2019 03 01; 155(3):370.
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Kaposi's sarcoma-associated herpesvirus infection promotes differentiation and polarization of monocytes into tumor-associated macrophages. Cell Cycle. 2017; 16(17):1611-1621.
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Non-HIV-related Kaposi sarcoma in 2 Hispanic patients arising in the setting of chronic venous insufficiency. Cutis. 2015 Jun; 95(6):E30-3.
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Probing the Solution Structure of I?B Kinase (IKK) Subunit ? and Its Interaction with Kaposi Sarcoma-associated Herpes Virus Flice-interacting Protein and IKK Subunit ß by EPR Spectroscopy. J Biol Chem. 2015 Jul 03; 290(27):16539-49.
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Bone marrow findings in HIV-positive patients with Kaposi sarcoma herpesvirus-associated multicentric Castleman disease. Am J Clin Pathol. 2013 May; 139(5):651-61.
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Expression of human beta-defensin-2 in intratumoral vascular endothelium and in endothelial cells induced by transforming growth factor beta. Peptides. 2010 Feb; 31(2):195-201.
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Inhibition of interferon regulatory factor 7 (IRF7)-mediated interferon signal transduction by the Kaposi's sarcoma-associated herpesvirus viral IRF homolog vIRF3. J Virol. 2007 Aug; 81(15):8282-92.
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KSHV/HHV8-associated primary cutaneous plasmablastic lymphoma in a patient with Castleman's disease and Kaposi's sarcoma. J Cutan Pathol. 2006 Sep; 33 Suppl 2:46-51.