 Solubility
"Solubility" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The ability of a substance to be dissolved, i.e. to form a solution with another substance. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
| Descriptor ID |
D012995
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| MeSH Number(s) |
G02.842.800
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Solubility".
Below are MeSH descriptors whose meaning is more specific than "Solubility".
This graph shows the total number of publications written about "Solubility" by people in this website by year, and whether "Solubility" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 2 | 2 | | 1984 | 0 | 1 | 1 | | 1986 | 0 | 5 | 5 | | 1989 | 0 | 5 | 5 | | 1990 | 0 | 2 | 2 | | 1991 | 0 | 1 | 1 | | 1992 | 0 | 1 | 1 | | 1994 | 0 | 2 | 2 | | 1995 | 0 | 3 | 3 | | 1996 | 0 | 3 | 3 | | 1997 | 0 | 4 | 4 | | 1998 | 0 | 3 | 3 | | 1999 | 0 | 4 | 4 | | 2000 | 0 | 4 | 4 | | 2001 | 0 | 2 | 2 | | 2002 | 0 | 4 | 4 | | 2003 | 0 | 7 | 7 | | 2004 | 0 | 4 | 4 | | 2005 | 0 | 3 | 3 | | 2006 | 0 | 3 | 3 | | 2007 | 0 | 6 | 6 | | 2008 | 0 | 3 | 3 | | 2009 | 0 | 6 | 6 | | 2010 | 0 | 4 | 4 | | 2011 | 0 | 2 | 2 | | 2012 | 0 | 5 | 5 | | 2013 | 0 | 3 | 3 | | 2014 | 0 | 5 | 5 | | 2015 | 0 | 6 | 6 | | 2016 | 0 | 3 | 3 | | 2017 | 1 | 8 | 9 | | 2018 | 1 | 1 | 2 | | 2019 | 0 | 6 | 6 | | 2020 | 0 | 9 | 9 | | 2021 | 0 | 5 | 5 | | 2022 | 0 | 3 | 3 |
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Below are the most recent publications written about "Solubility" by people in Profiles.
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Guo Y, Sun CC. Profound effects of gastric secretion rate variations on the precipitation of erlotinib in duodenum - An in vitro investigation. Int J Pharm. 2022 May 10; 619:121722.
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Gao Z, Liu S, Sun CC. Complexation with aromatic carboxylic acids expands the solid-state landscape of berberine. Int J Pharm. 2022 Apr 05; 617:121587.
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Wang K, Hao Y, Wang C, Zhao X, He X, Sun CC. Simultaneous improvement of physical stability, dissolution, bioavailability, and antithrombus efficacy of Aspirin and Ligustrazine through cocrystallization. Int J Pharm. 2022 Mar 25; 616:121541.
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Guo Y, Sun CC. Formulation strategies for mitigating dissolution reduction of p-aminobenzoic acid by sodium lauryl sulfate through diffusion layer modulation. Int J Pharm. 2022 Jan 05; 611:121310.
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Guo Y, Sun CC. Pharmaceutical Lauryl Sulfate Salts: Prevalence, Formation Rules, and Formulation Implications. Mol Pharm. 2022 02 07; 19(2):432-439.
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Song S, Wang C, Wang S, Siegel RA, Sun CC. Efficient development of sorafenib tablets with improved oral bioavailability enabled by coprecipitated amorphous solid dispersion. Int J Pharm. 2021 Dec 15; 610:121216.
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Wang L, Liu S, Chen JM, Wang YX, Sun CC. Novel Salt-Cocrystals of Berberine Hydrochloride with Aliphatic Dicarboxylic Acids: Odd-Even Alternation in Physicochemical Properties. Mol Pharm. 2021 04 05; 18(4):1758-1767.
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Damo M, Wilson DS, Watkins EA, Hubbell JA. Soluble N-Acetylgalactosamine-Modified Antigens Enhance Hepatocyte-Dependent Antigen Cross-Presentation and Result in Antigen-Specific CD8+ T Cell Tolerance Development. Front Immunol. 2021; 12:555095.
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Calahan JL, Paul S, Yanez EG, DeNeve D, Sun CC, Munson EJ. The impact of solid-state form, water content and surface area of magnesium stearate on lubrication efficiency, tabletability, and dissolution. Pharm Dev Technol. 2021 Feb; 26(2):150-156.
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Chen H, Wang C, Liu S, Sun CC. Development of piroxicam mini-tablets enabled by spherical cocrystallization. Int J Pharm. 2020 Nov 30; 590:119953.
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