Hydroxyzine
"Hydroxyzine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
Descriptor ID |
D006919
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MeSH Number(s) |
D03.383.606.515
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Concept/Terms |
Hydroxyzine- Hydroxyzine
- 2-(2-(4-((4-Chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)ethanol
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Below are MeSH descriptors whose meaning is more general than "Hydroxyzine".
Below are MeSH descriptors whose meaning is more specific than "Hydroxyzine".
This graph shows the total number of publications written about "Hydroxyzine" by people in this website by year, and whether "Hydroxyzine" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1989 | 1 | 2 | 3 | 1991 | 1 | 0 | 1 | 1998 | 0 | 1 | 1 | 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hydroxyzine" by people in Profiles.
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Stanford EJ, Chen A, Wan GJ, Lunacsek OE, Sand PK. Treatment modalities, health care resource utilization, and costs in patients diagnosed with interstitial cystitis. Am J Obstet Gynecol. 2008 Jul; 199(1):71.e1-10.
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Beppu T, Ogawa M, Yamanaka T, Egami H, Ohara C, Masuda Y, Kudo S, Kuramoto M, Doi K, Matsuda T. [Clinical evaluation of Azasetron Hydrochloride: a new selective 5-HT3 receptor antagonist--antiemetic profile and plasma concentration in transcatheter arterial chemoembolization using CDDP for unresectable hepatocellular carcinoma]. Gan To Kagaku Ryoho. 1998 Jul; 25(8):1197-202.
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Naclerio RM. Additional properties of cetirizine, a new H1 antagonist. Allergy Proc. 1991 May-Jun; 12(3):187-91.
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Baroody F, Proud D, Kagey-Sobotka A, Freidhoff L, Norman PS, Lichtenstein LM, Naclerio RM. The effects of H1 antihistamines on the early allergic response. Ann Allergy. 1989 Dec; 63(6 Pt 2):551-5.
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Togias AG, Proud D, Kagey-Sobotka A, Freidhoff L, Lichtenstein LM, Naclerio RM. In vivo and in vitro effects of antihistamines on mast cell mediator release: a potentially important property in the treatment of allergic disease. Ann Allergy. 1989 Nov; 63(5):465-9.
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Naclerio RM, Proud D, Kagey-Sobotka A, Freidhoff L, Norman PS, Lichtenstein LM. The effect of cetirizine on early allergic response. Laryngoscope. 1989 Jun; 99(6 Pt 1):596-9.
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SHALOWITZ M. Evaluation of an ataraxic (hydroxyzine) in long-term therapy. Int Rec Med. 1961 Jun; 174:357-61.
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SHALOWITZ M. Hydroxyzine: a new therapeutic agent for senile anxiety states; a preliminary report. Geriatrics. 1956 Jul; 11(7):312-5.
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