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Last Name

Yuxuan Miao

TitleAssistant Professor
InstitutionUniversity of Chicago
DepartmentBen May Department of Cancer Research
AddressChicago IL 60637
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    Collapse Overview 
    Collapse overview
    Yuxuan (Phoenix) Miao’s research focuses on understanding how normal and cancerous epithelial tissue adapt to inflammation, with a special interest in dissecting how stem cells residing in these tissues interact with the immune system to maintain normal tissue fitness and achieve cancer immune evasion.

    Collapse Biography 
    Collapse education and training
    Rockefeller University, New York, NYPostdoc08/2020Stem cell and cancer biology
    Duke University School of Medicine, Durham, NCPhD06/2015Immunology
    Beijing Institute of Technology, Beijing, ChinaB.S.06/2008Biotechnology
    Collapse awards and honors
    2019 - 2023NCI K99/R00 Pathway to Independence Award, Rockefeller University
    2019 - 2020Robertson Therapeutic Development Foundation Award, Rockefeller University
    2016 - 2019Jane Coffin Childs Fellowship, Rockefeller University
    2015Mitchell Meritorious Research Award, Duke University
    2009Duke Chancellor Award, Duke University

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    Collapse Research 
    Collapse research activities and funding
    R00CA237859     (MIAO, YUXUAN)Aug 1, 2020 - Jul 31, 2023
    Dissecting Stem Cell Intrinsic Signaling Driving Tumor Relapse from Immunotherapy
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Wu J, Hayes BW, Phoenix C, Macias GS, Miao Y, Choi HW, Hughes FM, Todd Purves J, Lee Reinhardt R, Abraham SN. A highly polarized TH2 bladder response to infection promotes epithelial repair at the expense of preventing new infections. Nat Immunol. 2020 06; 21(6):671-683. PMID: 32424366.
      View in: PubMed
    2. Adam RC, Yang H, Ge Y, Infarinato NR, Gur-Cohen S, Miao Y, Wang P, Zhao Y, Lu CP, Kim JE, Ko JY, Paik SS, Gronostajski RM, Kim J, Krueger JG, Zheng D, Fuchs E. NFI transcription factors provide chromatin access to maintain stem cell identity while preventing unintended lineage fate choices. Nat Cell Biol. 2020 06; 22(6):640-650. PMID: 32393888.
      View in: PubMed
    3. Gur-Cohen S, Yang H, Baksh SC, Miao Y, Levorse J, Kataru RP, Liu X, de la Cruz-Racelis J, Mehrara BJ, Fuchs E. Stem cell-driven lymphatic remodeling coordinates tissue regeneration. Science. 2019 12 06; 366(6470):1218-1225. PMID: 31672914.
      View in: PubMed
    4. Miao Y, Yang H, Levorse J, Yuan S, Polak L, Sribour M, Singh B, Rosenblum MD, Fuchs E. Adaptive Immune Resistance Emerges from Tumor-Initiating Stem Cells. Cell. 2019 05 16; 177(5):1172-1186.e14. PMID: 31031009.
      View in: PubMed
    5. Miao Y, Bist P, Wu J, Zhao Q, Li QJ, Wan Y, Abraham SN. Collaboration between Distinct Rab Small GTPase Trafficking Circuits Mediates Bacterial Clearance from the Bladder Epithelium. Cell Host Microbe. 2017 Sep 13; 22(3):330-342.e4. PMID: 28910634.
      View in: PubMed
    6. Choi HW, Bowen SE, Miao Y, Chan CY, Miao EA, Abrink M, Moeser AJ, Abraham SN. Loss of Bladder Epithelium Induced by Cytolytic Mast Cell Granules. Immunity. 2016 12 20; 45(6):1258-1269. PMID: 27939674.
      View in: PubMed
    7. Miao Y, Wu J, Abraham SN. Ubiquitination of Innate Immune Regulator TRAF3 Orchestrates Expulsion of Intracellular Bacteria by Exocyst Complex. Immunity. 2016 07 19; 45(1):94-105. PMID: 27438768.
      View in: PubMed
    8. Abraham SN, Miao Y. The nature of immune responses to urinary tract infections. Nat Rev Immunol. 2015 Oct; 15(10):655-63. PMID: 26388331.
      View in: PubMed
    9. Miao Y, Li G, Zhang X, Xu H, Abraham SN. A TRP Channel Senses Lysosome Neutralization by Pathogens to Trigger Their Expulsion. Cell. 2015 Jun 04; 161(6):1306-19. PMID: 26027738.
      View in: PubMed
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