 Ketoconazole
"Ketoconazole" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Broad spectrum antifungal agent used for long periods at high doses, especially in immunosuppressed patients.
| Descriptor ID |
D007654
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| MeSH Number(s) |
D03.383.606.560
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| Concept/Terms |
Nizoral- Nizoral
- Janssen Brand of Ketoconazole
- Ketoconazole Janssen Brand
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Below are MeSH descriptors whose meaning is more general than "Ketoconazole".
Below are MeSH descriptors whose meaning is more specific than "Ketoconazole".
This graph shows the total number of publications written about "Ketoconazole" by people in this website by year, and whether "Ketoconazole" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 0 | 1 | 1 | | 1984 | 0 | 1 | 1 | | 1986 | 1 | 0 | 1 | | 1987 | 1 | 1 | 2 | | 1989 | 1 | 0 | 1 | | 1990 | 1 | 0 | 1 | | 1994 | 1 | 0 | 1 | | 1996 | 0 | 1 | 1 | | 2000 | 1 | 0 | 1 | | 2004 | 2 | 1 | 3 | | 2005 | 1 | 0 | 1 | | 2006 | 0 | 1 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 1 | 2 | | 2009 | 1 | 1 | 2 | | 2012 | 0 | 1 | 1 | | 2013 | 1 | 1 | 2 | | 2014 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ketoconazole" by people in Profiles.
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House L, Seminerio MJ, Mirkov S, Ramirez J, Skor M, Sachleben JR, Isikbay M, Singhal H, Greene GL, Vander Griend D, Conzen SD, Ratain MJ. Metabolism of megestrol acetate in vitro and the role of oxidative metabolites. Xenobiotica. 2018 Oct; 48(10):973-983.
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Kim W, Zhang L, Wilton JH, Fetterly G, Mohler JL, Weinberg V, Morse A, Szmulewitz RZ, Friedlander TW, Fong L, Lin AM, Harzstark AL, Molina A, Small EJ, Ryan CJ. Sequential use of the androgen synthesis inhibitors ketoconazole and abiraterone acetate in castration-resistant prostate cancer and the predictive value of circulating androgens. Clin Cancer Res. 2014 Dec 15; 20(24):6269-76.
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Hoeh MP, Levine LA. Prevention of recurrent ischemic priapism with ketoconazole: evolution of a treatment protocol and patient outcomes. J Sex Med. 2014 Jan; 11(1):197-204.
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Aggarwal R, Halabi S, Kelly WK, George D, Mahoney JF, Millard F, Stadler WM, Morris MJ, Kantoff P, Monk JP, Carducci M, Small EJ. The effect of prior androgen synthesis inhibition on outcomes of subsequent therapy with docetaxel in patients with metastatic castrate-resistant prostate cancer: results from a retrospective analysis of a randomized phase 3 clinical trial (CALGB 90401) (Alliance). Cancer. 2013 Oct 15; 119(20):3636-43.
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Cohen EE, Wu K, Hartford C, Kocherginsky M, Eaton KN, Zha Y, Nallari A, Maitland ML, Fox-Kay K, Moshier K, House L, Ramirez J, Undevia SD, Fleming GF, Gajewski TF, Ratain MJ. Phase I studies of sirolimus alone or in combination with pharmacokinetic modulators in advanced cancer patients. Clin Cancer Res. 2012 Sep 01; 18(17):4785-93.
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Abern MR, Levine LA. Ketoconazole and prednisone to prevent recurrent ischemic priapism. J Urol. 2009 Oct; 182(4):1401-6.
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Cetner A, Krunic A, Tesic V, Janda W. Tinea capitis due to Trichophyton soudanense in Chicago, Illinois: report of a case. Pediatr Dermatol. 2009 Mar-Apr; 26(2):226-8.
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Levine LA. Re: Oral ketoconazole for prevention of postoperative penile erection: a placebo controlled, randomized, double-blind trial: B. J. DeCastro, R. A. Costabile, L. P. McMann and A. C. Peterson. J Urol 2008; 179: 1930-1932. J Urol. 2008 Nov; 180(5):2260; author reply 2260-1.
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Li J, Byrne ME, Chang E, Jiang Y, Donkin SS, Buhman KK, Burgess JR, Teegarden D. 1alpha,25-Dihydroxyvitamin D hydroxylase in adipocytes. J Steroid Biochem Mol Biol. 2008 Nov; 112(1-3):122-6.
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Yong WP, Desai AA, Innocenti F, Ramirez J, Shepard D, Kobayashi K, House L, Fleming GF, Vogelzang NJ, Schilsky RL, Ratain MJ. Pharmacokinetic modulation of oral etoposide by ketoconazole in patients with advanced cancer. Cancer Chemother Pharmacol. 2007 Nov; 60(6):811-9.
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