 Langerhans Cells
"Langerhans Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Recirculating, dendritic, antigen-presenting cells containing characteristic racket-shaped granules (Birbeck granules). They are found principally in the stratum spinosum of the EPIDERMIS and are rich in Class II MAJOR HISTOCOMPATIBILITY COMPLEX molecules. Langerhans cells were the first dendritic cell to be described and have been a model of study for other dendritic cells (DCs), especially other migrating DCs such as dermal DCs and INTERSTITIAL DENDRITIC CELLS.
| Descriptor ID |
D007801
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| MeSH Number(s) |
A11.066.270.500 A11.436.270.545 A15.382.066.270.500 A15.382.812.260.500
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| Concept/Terms |
Langerhans Cells- Langerhans Cells
- Cells, Langerhans
- Epidermal Dendritic Cells
- Dendritic Cells, Epidermal
- Cell, Epidermal Dendritic
- Cells, Epidermal Dendritic
- Dendritic Cell, Epidermal
- Epidermal Dendritic Cell
Skin Dendritic Cells- Skin Dendritic Cells
- Cell, Skin Dendritic
- Cells, Skin Dendritic
- Dendritic Cell, Skin
- Skin Dendritic Cell
- Dendritic Cells, Skin
Dermal Dendritic Cells- Dermal Dendritic Cells
- Cell, Dermal Dendritic
- Cells, Dermal Dendritic
- Dendritic Cell, Dermal
- Dermal Dendritic Cell
- Dendritic Cells, Dermal
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Below are MeSH descriptors whose meaning is more general than "Langerhans Cells".
Below are MeSH descriptors whose meaning is more specific than "Langerhans Cells".
This graph shows the total number of publications written about "Langerhans Cells" by people in this website by year, and whether "Langerhans Cells" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 1 | 0 | 1 | | 1983 | 1 | 0 | 1 | | 1988 | 0 | 1 | 1 | | 1990 | 1 | 0 | 1 | | 1992 | 1 | 0 | 1 | | 1995 | 0 | 1 | 1 | | 2003 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Langerhans Cells" by people in Profiles.
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Shipman WD, Chyou S, Ramanathan A, Izmirly PM, Sharma S, Pannellini T, Dasoveanu DC, Qing X, Magro CM, Granstein RD, Lowes MA, Pamer EG, Kaplan DH, Salmon JE, Mehrara BJ, Young JW, Clancy RM, Blobel CP, Lu TT. A protective Langerhans cell-keratinocyte axis that is dysfunctional in photosensitivity. Sci Transl Med. 2018 08 15; 10(454).
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Kim YH, Gratzinger D, Harrison C, Brody JD, Czerwinski DK, Ai WZ, Morales A, Abdulla F, Xing L, Navi D, Tibshirani RJ, Advani RH, Lingala B, Shah S, Hoppe RT, Levy R. In situ vaccination against mycosis fungoides by intratumoral injection of a TLR9 agonist combined with radiation: a phase 1/2 study. Blood. 2012 Jan 12; 119(2):355-63.
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Mahe B, Vogt A, Liard C, Duffy D, Abadie V, Bonduelle O, Boissonnas A, Sterry W, Verrier B, Blume-Peytavi U, Combadiere B. Nanoparticle-based targeting of vaccine compounds to skin antigen-presenting cells by hair follicles and their transport in mice. J Invest Dermatol. 2009 May; 129(5):1156-64.
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Molinero LL, Zhou P, Wang Y, Harlin H, Kee B, Abraham C, Alegre ML. Epidermal Langerhans cells promote skin allograft rejection in mice with NF-kappa B-impaired T cells. Am J Transplant. 2008 Jan; 8(1):21-31.
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Gordon KB, Bonish BK, Patel T, Leonardi CL, Nickoloff BJ. The tumour necrosis factor-alpha inhibitor adalimumab rapidly reverses the decrease in epidermal Langerhans cell density in psoriatic plaques. Br J Dermatol. 2005 Nov; 153(5):945-53.
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Serbina NV, Pamer EG. Immunology. Giving credit where credit is due. Science. 2003 Sep 26; 301(5641):1856-7.
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Connor JP, Ferrer K, Kane JP, Goldberg JM. Evaluation of Langerhans' cells in the cervical epithelium of women with cervical intraepithelial neoplasia. Gynecol Oncol. 1999 Oct; 75(1):130-5.
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Itagaki S, Ishii Y, Lee MJ, Doi K. Dermal histology of hairless rat derived from Wistar strain. Exp Anim. 1995 Oct; 44(4):279-84.
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Becker Y. Dengue fever virus and Japanese encephalitis virus synthetic peptides, with motifs to fit HLA class I haplotypes prevalent in human populations in endemic regions, can be used for application to skin Langerhans cells to prime antiviral CD8+ cytotoxic T cells (CTLs)--a novel approach to the protection of humans. Virus Genes. 1994 Sep; 9(1):33-45.
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Yu RC, Morris JF, Pritchard J, Chu TC. Defective alloantigen-presenting capacity of 'Langerhans cell histiocytosis cells'. Arch Dis Child. 1992 Nov; 67(11):1370-2.
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