 Giant Cells
"Giant Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Multinucleated masses produced by the fusion of many cells; often associated with viral infections. In AIDS, they are induced when the envelope glycoprotein of the HIV virus binds to the CD4 antigen of uninfected neighboring T4 cells. The resulting syncytium leads to cell death and thus may account for the cytopathic effect of the virus.
| Descriptor ID |
D015726
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| MeSH Number(s) |
A11.500
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| Concept/Terms |
Giant Cells- Giant Cells
- Cell, Giant
- Cells, Giant
- Giant Cell
- Syncytium
- Polykaryocytes
- Polykaryocyte
- Syncytia
- Giant Cells, Multinucleated
- Cell, Multinucleated Giant
- Cells, Multinucleated Giant
- Giant Cell, Multinucleated
- Multinucleated Giant Cell
- Multinucleated Giant Cells
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Below are MeSH descriptors whose meaning is more general than "Giant Cells".
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This graph shows the total number of publications written about "Giant Cells" by people in this website by year, and whether "Giant Cells" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 0 | 1 | 1 | | 1994 | 1 | 0 | 1 | | 1996 | 0 | 1 | 1 | | 1999 | 2 | 1 | 3 | | 2001 | 0 | 2 | 2 | | 2002 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 1 | 2 | 3 | | 2010 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Giant Cells" by people in Profiles.
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Van de Sande DV, Kopljar I, Maaike A, Teisman A, Gallacher DJ, Bart L, Snyders DJ, Leybaert L, Lu HR, Labro AJ. The resting membrane potential of hSC-CM in a syncytium is more hyperpolarised than that of isolated cells. Channels (Austin). 2021 12; 15(1):239-252.
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Lapadat R, Nam MW, Mehrotra S, Velankar M, Pambuccian SE. Mulberry cells in the thyroid: warthin-finkeldey-like cells in hashimoto thyroiditis-associated lymphoma. Diagn Cytopathol. 2017 Mar; 45(3):212-216.
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Hazebroek MR, van Paassen P, Weerwind PW, Cooper LT, Uriel N, Caliskan K, de Vries B, Maessen JG, Autschbach R, Heymans S, Donker DW. A passionate endurance cyclist ultimately survives sudden death in right ventricular giant cell myocarditis. Int J Cardiol. 2014 Jan 01; 170(3):e74-5.
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Torbenson M, Hart J, Westerhoff M, Azzam RK, Elgendi A, Mziray-Andrew HC, Kim GE, Scheimann A. Neonatal giant cell hepatitis: histological and etiological findings. Am J Surg Pathol. 2010 Oct; 34(10):1498-503.
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Chang A, Peutz-Kootstra CJ, Kowalewska J, Logar CM, Gitomer JJ, Davis CL, Shankland SJ, Alpers CE, Smith KD. Giant cell tubulitis with tubular basement membrane immune deposits: a report of two cases after cardiac valve replacement surgery. Clin J Am Soc Nephrol. 2006 Sep; 1(5):920-4.
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Takayama H, Aldea GS, Verrier ED, Salerno CT, Levy WC, Fishbein DP. Successful management of asystole with an isolated left ventricular assist device. J Heart Lung Transplant. 2006 Apr; 25(4):490-2.
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Bissonnette ML, Connolly SA, Young DF, Randall RE, Paterson RG, Lamb RA. Analysis of the pH requirement for membrane fusion of different isolates of the paramyxovirus parainfluenza virus 5. J Virol. 2006 Mar; 80(6):3071-7.
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Paner GP, Gasilionis V, Hammadeh R. A retroperitoneal mass in an elderly woman. Pleomorphic rhabdomyosarcoma, classic variant, with reactive osteoclast-like giant cells. Arch Pathol Lab Med. 2005 May; 129(5):703-5.
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Nakayama Y, Su W, Ohguchi A, Nakayama H, Doi K. Experimental encephalomyocarditis virus infection in pregnant mice. Exp Mol Pathol. 2004 Oct; 77(2):133-7.
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Ahmed A, Jevremovic D, Suzuki K, Kottke T, Thompson J, Emery S, Harrington K, Bateman A, Vile R. Intratumoral expression of a fusogenic membrane glycoprotein enhances the efficacy of replicating adenovirus therapy. Gene Ther. 2003 Sep; 10(19):1663-71.
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