"Giant Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Multinucleated masses produced by the fusion of many cells; often associated with viral infections. In AIDS, they are induced when the envelope glycoprotein of the HIV virus binds to the CD4 antigen of uninfected neighboring T4 cells. The resulting syncytium leads to cell death and thus may account for the cytopathic effect of the virus.
| Descriptor ID |
D015726
|
| MeSH Number(s) |
A11.500
|
| Concept/Terms |
Giant Cells- Giant Cells
- Cell, Giant
- Cells, Giant
- Giant Cell
- Syncytium
- Polykaryocytes
- Polykaryocyte
- Syncytia
- Giant Cells, Multinucleated
- Cell, Multinucleated Giant
- Cells, Multinucleated Giant
- Giant Cell, Multinucleated
- Multinucleated Giant Cell
- Multinucleated Giant Cells
|
Below are MeSH descriptors whose meaning is more general than "Giant Cells".
Below are MeSH descriptors whose meaning is more specific than "Giant Cells".
This graph shows the total number of publications written about "Giant Cells" by people in this website by year, and whether "Giant Cells" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1996 | 0 | 1 | 1 |
| 1999 | 2 | 1 | 3 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 2 | 3 |
| 2010 | 1 | 0 | 1 |
| 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Giant Cells" by people in Profiles.
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The resting membrane potential of hSC-CM in a syncytium is more hyperpolarised than that of isolated cells. Channels (Austin). 2021 12; 15(1):239-252.
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Monocyte progenitors give rise to multinucleated giant cells. Nat Commun. 2021 04 01; 12(1):2027.
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Mulberry cells in the thyroid: warthin-finkeldey-like cells in hashimoto thyroiditis-associated lymphoma. Diagn Cytopathol. 2017 Mar; 45(3):212-216.
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A passionate endurance cyclist ultimately survives sudden death in right ventricular giant cell myocarditis. Int J Cardiol. 2014 Jan 01; 170(3):e74-5.
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Neonatal giant cell hepatitis: histological and etiological findings. Am J Surg Pathol. 2010 Oct; 34(10):1498-503.
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Giant cell tubulitis with tubular basement membrane immune deposits: a report of two cases after cardiac valve replacement surgery. Clin J Am Soc Nephrol. 2006 Sep; 1(5):920-4.
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Successful management of asystole with an isolated left ventricular assist device. J Heart Lung Transplant. 2006 Apr; 25(4):490-2.
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Analysis of the pH requirement for membrane fusion of different isolates of the paramyxovirus parainfluenza virus 5. J Virol. 2006 Mar; 80(6):3071-7.
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A retroperitoneal mass in an elderly woman. Pleomorphic rhabdomyosarcoma, classic variant, with reactive osteoclast-like giant cells. Arch Pathol Lab Med. 2005 May; 129(5):703-5.
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Experimental encephalomyocarditis virus infection in pregnant mice. Exp Mol Pathol. 2004 Oct; 77(2):133-7.