Beta2-integrin adhesion caused by eotaxin but not IL-5 is blocked by PDE-4 inhibition and beta2-adrenoceptor activation in human eosinophils.

Beta2-integrin adhesion caused by eotaxin but not IL-5 is blocked by PDE-4 inhibition and beta2-adrenoceptor activation in human eosinophils. Pulm Pharmacol Ther. 2004; 17(2):73-9.

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subject areas

3',5'-Cyclic-AMP Phosphodiesterases
Adrenergic beta-2 Receptor Agonists
Adrenergic beta-Agonists
Albuterol
CD11b Antigen
CD18 Antigens
Cell Adhesion
Chemokine CCL11
Chemokines, CC
Cyclic Nucleotide Phosphodiesterases, Type 4
Drug Synergism
Enzyme Activation
Eosinophils
Group IV Phospholipases A2
Humans
In Vitro Techniques
Interleukin-5
Phosphodiesterase Inhibitors
Phospholipases A
Phosphorylation
Rolipram
Salmeterol Xinafoate
Up-Regulation

authors with profiles

Alan Leff