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OTS167 blocks FLT3 translation and synergizes with FLT3 inhibitors in FLT3 mutant acute myeloid leukemia.
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OTS167 blocks FLT3 translation and synergizes with FLT3 inhibitors in FLT3 mutant acute myeloid leukemia.
OTS167 blocks FLT3 translation and synergizes with FLT3 inhibitors in FLT3 mutant acute myeloid leukemia. Blood Cancer J. 2021 03 03; 11(3):48.
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PubMed
subject areas
Animals
Cell Line, Tumor
Drug Synergism
fms-Like Tyrosine Kinase 3
Humans
Leukemia, Myeloid, Acute
Mice
Mutation
Naphthyridines
Protein Biosynthesis
Protein Kinase Inhibitors
authors with profiles
Olatoyosi Odenike
Wendy Stock
Jason X. Cheng
Caner Saygin