Oncogenesis of T-ALL and nonmalignant consequences of overexpressing intracellular NOTCH1.
Li X, Gounari F, Protopopov A, Khazaie K, von Boehmer H. Oncogenesis of T-ALL and nonmalignant consequences of overexpressing intracellular NOTCH1. J Exp Med. 2008 Nov 24; 205(12):2851-61.
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Adult
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Animals
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Bone Marrow Transplantation
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Cell Line, Tumor
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Cell Transformation, Neoplastic
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Gene Expression Profiling
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Gene Rearrangement, alpha-Chain T-Cell Antigen Receptor
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Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
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Genes, myc
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Genetic Vectors
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Genomic Instability
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Hematopoietic Stem Cells
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Humans
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Karyotyping
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Mice
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Mice, Inbred BALB C
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Mice, Nude
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Oligonucleotide Array Sequence Analysis
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Phenotype
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Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
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Proto-Oncogene Proteins c-myc
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Receptor, Notch1
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Receptors, Antigen, T-Cell, alpha-beta
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Tumor Suppressor Protein p53