HN Protein
"HN Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Glycoprotein from Sendai, para-influenza, Newcastle Disease, and other viruses that participates in binding the virus to cell-surface receptors. The HN protein possesses both hemagglutinin and neuraminidase activity.
Descriptor ID |
D015707
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MeSH Number(s) |
D12.776.964.970.880.350 D23.050.327.461.350
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Concept/Terms |
HN Protein- HN Protein
- Protein, HN
- HANA Glycoprotein
- Glycoprotein, HANA
- Hemagglutinin-Neuraminidase Glycoprotein
- Glycoprotein, Hemagglutinin-Neuraminidase
- Hemagglutinin Neuraminidase Glycoprotein
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Below are MeSH descriptors whose meaning is more general than "HN Protein".
Below are MeSH descriptors whose meaning is more specific than "HN Protein".
This graph shows the total number of publications written about "HN Protein" by people in this website by year, and whether "HN Protein" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 1 | 0 | 1 | 1998 | 0 | 1 | 1 | 1999 | 1 | 0 | 1 | 2001 | 1 | 0 | 1 | 2002 | 1 | 2 | 3 | 2008 | 1 | 1 | 2 | 2009 | 1 | 0 | 1 | 2010 | 0 | 1 | 1 | 2011 | 1 | 0 | 1 | 2012 | 2 | 1 | 3 |
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Below are the most recent publications written about "HN Protein" by people in Profiles.
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Welch BD, Liu Y, Kors CA, Leser GP, Jardetzky TS, Lamb RA. Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion protein. Proc Natl Acad Sci U S A. 2012 Oct 09; 109(41):16672-7.
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Bose S, Zokarkar A, Welch BD, Leser GP, Jardetzky TS, Lamb RA. Fusion activation by a headless parainfluenza virus 5 hemagglutinin-neuraminidase stalk suggests a modular mechanism for triggering. Proc Natl Acad Sci U S A. 2012 Sep 25; 109(39):E2625-34.
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Yuan P, Paterson RG, Leser GP, Lamb RA, Jardetzky TS. Structure of the ulster strain newcastle disease virus hemagglutinin-neuraminidase reveals auto-inhibitory interactions associated with low virulence. PLoS Pathog. 2012; 8(8):e1002855.
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Yuan P, Swanson KA, Leser GP, Paterson RG, Lamb RA, Jardetzky TS. Structure of the Newcastle disease virus hemagglutinin-neuraminidase (HN) ectodomain reveals a four-helix bundle stalk. Proc Natl Acad Sci U S A. 2011 Sep 06; 108(36):14920-5.
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Ravid D, Leser GP, Lamb RA. A role for caveolin 1 in assembly and budding of the paramyxovirus parainfluenza virus 5. J Virol. 2010 Oct; 84(19):9749-59.
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Connolly SA, Leser GP, Jardetzky TS, Lamb RA. Bimolecular complementation of paramyxovirus fusion and hemagglutinin-neuraminidase proteins enhances fusion: implications for the mechanism of fusion triggering. J Virol. 2009 Nov; 83(21):10857-68.
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Bissonnette ML, Donald JE, DeGrado WF, Jardetzky TS, Lamb RA. Functional analysis of the transmembrane domain in paramyxovirus F protein-mediated membrane fusion. J Mol Biol. 2009 Feb 13; 386(1):14-36.
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Yuan P, Leser GP, Demeler B, Lamb RA, Jardetzky TS. Domain architecture and oligomerization properties of the paramyxovirus PIV 5 hemagglutinin-neuraminidase (HN) protein. Virology. 2008 Sep 01; 378(2):282-91.
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Waning DL, Schmitt AP, Leser GP, Lamb RA. Roles for the cytoplasmic tails of the fusion and hemagglutinin-neuraminidase proteins in budding of the paramyxovirus simian virus 5. J Virol. 2002 Sep; 76(18):9284-97.
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Schmitt AP, Leser GP, Waning DL, Lamb RA. Requirements for budding of paramyxovirus simian virus 5 virus-like particles. J Virol. 2002 Apr; 76(8):3952-64.
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