Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity.

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Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity.

Stockton RA, Shenkar R, Awad IA, Ginsberg MH. Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity. J Exp Med. 2010 Apr 12; 207(4):881-96.

View in: PubMed

subject areas

1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
Animal Structures
Animals
Brain Edema
Capillary Permeability
Carrier Proteins
Edema, Cardiac
Endothelial Cells
Endothelium, Vascular
Hemangioma, Cavernous, Central Nervous System
Humans
Mice
Mice, Inbred C57BL
Mice, Mutant Strains
Microfilament Proteins
Microtubule-Associated Proteins
Mutation
Myosin Light Chains
Phosphorylation
Protein Binding
Protein Kinase Inhibitors
Proto-Oncogene Proteins
Pulmonary Edema
rhoA GTP-Binding Protein
rho-Associated Kinases
RNA, Small Interfering
Signal Transduction

authors with profiles

Joan H. Parks
Robert Shenkar
Issam Awad