 N-Formylmethionine
"N-Formylmethionine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formylmethionyl tRNA. This process occurs in Escherichia coli and other bacteria as well as in the mitochondria of eucaryotic cells.
| Descriptor ID |
D009239
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| MeSH Number(s) |
D02.886.030.676.450 D12.125.166.676.450
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "N-Formylmethionine".
Below are MeSH descriptors whose meaning is more specific than "N-Formylmethionine".
This graph shows the total number of publications written about "N-Formylmethionine" by people in this website by year, and whether "N-Formylmethionine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 0 | 1 | 1 | | 1999 | 1 | 0 | 1 | | 2001 | 1 | 1 | 2 | | 2005 | 1 | 0 | 1 |
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Below are the most recent publications written about "N-Formylmethionine" by people in Profiles.
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Ploss A, Tran A, Menet E, Leiner I, Pamer EG. Cross-recognition of N-formylmethionine peptides is a general characteristic of H2-M3-restricted CD8+ T cells. Infect Immun. 2005 Jul; 73(7):4423-6.
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Lauvau G, Pamer EG. CD8 T cell detection of bacterial infection: sniffing for formyl peptides derived from Mycobacterium tuberculosis. J Exp Med. 2001 May 21; 193(10):F35-9.
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Kerksiek KM, Busch DH, Pamer EG. Variable immunodominance hierarchies for H2-M3-restricted N-formyl peptides following bacterial infection. J Immunol. 2001 Jan 15; 166(2):1132-40.
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Chiu NM, Chun T, Fay M, Mandal M, Wang CR. The majority of H2-M3 is retained intracellularly in a peptide-receptive state and traffics to the cell surface in the presence of N-formylated peptides. J Exp Med. 1999 Aug 02; 190(3):423-34.
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Pamer EG, Wang CR, Flaherty L, Lindahl KF, Bevan MJ. H-2M3 presents a Listeria monocytogenes peptide to cytotoxic T lymphocytes. Cell. 1992 Jul 24; 70(2):215-23.
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