"Melatonin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant.
| Descriptor ID |
D008550
|
| MeSH Number(s) |
D03.633.100.473.914.481 D06.472.506
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Melatonin".
Below are MeSH descriptors whose meaning is more specific than "Melatonin".
This graph shows the total number of publications written about "Melatonin" by people in this website by year, and whether "Melatonin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 |
| 1994 | 2 | 0 | 2 |
| 1996 | 1 | 0 | 1 |
| 1998 | 2 | 0 | 2 |
| 1999 | 2 | 1 | 3 |
| 2000 | 3 | 0 | 3 |
| 2001 | 1 | 1 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 3 | 1 | 4 |
| 2005 | 1 | 0 | 1 |
| 2007 | 1 | 1 | 2 |
| 2009 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2013 | 1 | 3 | 4 |
| 2014 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2020 | 1 | 1 | 2 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Melatonin" by people in Profiles.
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Pan-cancer analyses reveal genomics and clinical characteristics of the melatonergic regulators in cancer. J Pineal Res. 2021 Oct; 71(3):e12758.
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A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19. PLoS Biol. 2020 11; 18(11):e3000970.
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Melatonin reverses nasopharyngeal carcinoma cisplatin chemoresistance by inhibiting the Wnt/?-catenin signaling pathway. Aging (Albany NY). 2020 03 23; 12(6):5423-5438.
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Relationship between Intrinsically Photosensitive Ganglion Cell Function and Circadian Regulation in Diabetic Retinopathy. Sci Rep. 2020 01 31; 10(1):1560.
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Impact of Common Diabetes Risk Variant in MTNR1B on Sleep, Circadian, and Melatonin Physiology. Diabetes. 2016 06; 65(6):1741-51.
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Headache and sleep: also assess circadian rhythm sleep disorders: a response. Headache. 2014 Jan; 54(1):178.
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Acute downregulation of Type II and Type III iodothyronine deiodinases by photoperiod in peripubertal male and female Siberian hamsters. Gen Comp Endocrinol. 2013 Nov 01; 193:72-8.
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Impaired leukocyte trafficking and skin inflammatory responses in hamsters lacking a functional circadian system. Brain Behav Immun. 2013 Aug; 32:94-104.
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Photoperiod history-dependent responses to intermediate day lengths engage hypothalamic iodothyronine deiodinase type III mRNA expression. Am J Physiol Regul Integr Comp Physiol. 2013 Apr 15; 304(8):R628-35.
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Rapid induction of hypothalamic iodothyronine deiodinase expression by photoperiod and melatonin in juvenile Siberian hamsters (Phodopus sungorus). Endocrinology. 2013 Feb; 154(2):831-41.