Lupus Coagulation Inhibitor
"Lupus Coagulation Inhibitor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antiphospholipid antibody found in association with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; and in a variety of other diseases as well as in healthy individuals. In vitro, the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications, including fetal death and spontaneous abortion, as well as a variety of hematologic and neurologic complications.
Descriptor ID |
D016682
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MeSH Number(s) |
D12.776.124.486.485.114.323.210.600 D12.776.124.790.651.114.323.210.600 D12.776.377.715.548.114.323.210.600 D23.113.475
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Concept/Terms |
Lupus Coagulation Inhibitor- Lupus Coagulation Inhibitor
- Inhibitor, Lupus Coagulation
- Coagulation Inhibitor, Lupus
- Lupus Anticoagulant
- Anticoagulant, Lupus
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Below are MeSH descriptors whose meaning is more general than "Lupus Coagulation Inhibitor".
Below are MeSH descriptors whose meaning is more specific than "Lupus Coagulation Inhibitor".
This graph shows the total number of publications written about "Lupus Coagulation Inhibitor" by people in this website by year, and whether "Lupus Coagulation Inhibitor" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1986 | 0 | 1 | 1 | 1987 | 0 | 1 | 1 | 1989 | 0 | 1 | 1 | 1991 | 0 | 1 | 1 | 1994 | 1 | 0 | 1 | 1997 | 0 | 1 | 1 | 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lupus Coagulation Inhibitor" by people in Profiles.
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Lockshin MD, Kim M, Laskin CA, Guerra M, Branch DW, Merrill J, Petri M, Porter TF, Sammaritano L, Stephenson MD, Buyon J, Salmon JE. Prediction of adverse pregnancy outcome by the presence of lupus anticoagulant, but not anticardiolipin antibody, in patients with antiphospholipid antibodies. Arthritis Rheum. 2012 Jul; 64(7):2311-8.
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Herrera FA, Lee CK, Kryger G, Roostaeian J, Safa B, Lohman RF, Gottlieb LJ, Walton RL. Microsurgery in the hypercoagulable patient: review of the literature. J Reconstr Microsurg. 2012 Jun; 28(5):305-12.
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Desjardins MK, Stephenson MD. "Information-rich" reproductive outcomes in carriers of a structural chromosome rearrangement ascertained on the basis of recurrent pregnancy loss. Fertil Steril. 2012 Apr; 97(4):894-903.
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Bussen SS, Steck T. Thyroid antibodies and their relation to antithrombin antibodies, anticardiolipin antibodies and lupus anticoagulant in women with recurrent spontaneous abortions (antithyroid, anticardiolipin and antithrombin autoantibodies and lupus anticoagulant in habitual aborters). Eur J Obstet Gynecol Reprod Biol. 1997 Aug; 74(2):139-43.
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Olson JC, Konkol RJ, Gill JC, Dobyns WB, Coull BM. Childhood stroke and lupus anticoagulant. Pediatr Neurol. 1994 Feb; 10(1):54-7.
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van Besien K, Hoffman R, Golichowski A. Pregnancy associated with lupus anticoagulant and heparin induced thrombocytopenia: management with a low molecular weight heparinoid. Thromb Res. 1991 Apr; 62(1-2):23-9.
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Heckerling PS, Froelich CJ, Schade SG. Retinal vein thrombosis in a patient with pernicious anemia and anticardiolipin antibodies. J Rheumatol. 1989 Aug; 16(8):1144-6.
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Pulido JS, Ward LM, Fishman GA, Goodwin JA, Froelich CJ, Sanghvi JP. Antiphospholipid antibodies associated with retinal vascular disease. Retina. 1987; 7(4):215-8.
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Asherson RA, Morgan SH, Harris EN, Gharavi AE, Krausz T, Hughes GR. Arterial occlusion causing large bowel infarction--a reflection of clotting diathesis in SLE. Clin Rheumatol. 1986 Jan; 5(1):102-6.
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