 Nafarelin
"Nafarelin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent synthetic agonist of GONADOTROPIN-RELEASING HORMONE with 3-(2-naphthyl)-D-alanine substitution at residue 6. Nafarelin has been used in the treatments of central PRECOCIOUS PUBERTY and ENDOMETRIOSIS.
| Descriptor ID |
D017274
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| MeSH Number(s) |
D06.472.699.327.740.320.580 D12.644.400.400.740.320.580 D12.644.456.460.600 D12.644.548.365.740.320.580 D12.776.641.650.405.740.320.580
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nafarelin".
Below are MeSH descriptors whose meaning is more specific than "Nafarelin".
This graph shows the total number of publications written about "Nafarelin" by people in this website by year, and whether "Nafarelin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1986 | 0 | 1 | 1 | | 1989 | 0 | 3 | 3 | | 1990 | 0 | 1 | 1 | | 1992 | 0 | 2 | 2 | | 1993 | 4 | 0 | 4 | | 1994 | 2 | 2 | 4 | | 1995 | 1 | 0 | 1 | | 1996 | 2 | 0 | 2 | | 1997 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nafarelin" by people in Profiles.
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Carel JC, Eugster EA, Rogol A, Ghizzoni L, Palmert MR. Consensus statement on the use of gonadotropin-releasing hormone analogs in children. Pediatrics. 2009 Apr; 123(4):e752-62.
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Levrant SG, Barnes RB, Rosenfield RL. A pilot study of the human chorionic gonadotrophin test for ovarian hyperandrogenism. Hum Reprod. 1997 Jul; 12(7):1416-20.
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Rosenthal IM, Refetoff S, Rich B, Barnes RB, Sunthornthepvarakul T, Parma J, Rosenfield RL. Response to challenge with gonadotropin-releasing hormone agonist in a mother and her two sons with a constitutively activating mutation of the luteinizing hormone receptor--a clinical research center study. J Clin Endocrinol Metab. 1996 Oct; 81(10):3802-6.
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Rosenfield RL, Perovic N, Ehrmann DA, Barnes RB. Acute hormonal responses to the gonadotropin releasing hormone agonist leuprolide: dose-response studies and comparison to nafarelin--a clinical research center study. J Clin Endocrinol Metab. 1996 Sep; 81(9):3408-11.
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Ghai K, Cara JF, Rosenfield RL. Gonadotropin releasing hormone agonist (nafarelin) test to differentiate gonadotropin deficiency from constitutionally delayed puberty in teen-age boys--a clinical research center study. J Clin Endocrinol Metab. 1995 Oct; 80(10):2980-6.
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Rosenfield RL, Barnes RB, Ehrmann DA. Studies of the nature of 17-hydroxyprogesterone hyperresonsiveness to gonadotropin-releasing hormone agonist challenge in functional ovarian hyperandrogenism. J Clin Endocrinol Metab. 1994 Dec; 79(6):1686-92.
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Barnes RB, Rosenfield RL, Ehrmann DA, Cara JF, Cuttler L, Levitsky LL, Rosenthal IM. Ovarian hyperandrogynism as a result of congenital adrenal virilizing disorders: evidence for perinatal masculinization of neuroendocrine function in women. J Clin Endocrinol Metab. 1994 Nov; 79(5):1328-33.
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Ghai K, Rosenfield RL. Maturation of the normal pituitary-testicular axis, as assessed by gonadotropin-releasing hormone agonist challenge. J Clin Endocrinol Metab. 1994 Jun; 78(6):1336-40.
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Rosenfield RL. Selection of children with precocious puberty for treatment with gonadotropin releasing hormone analogs. J Pediatr. 1994 Jun; 124(6):989-91.
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Goodpasture JC, Ghai K, Cara JF, Rosenfield RL. Potential of gonadotropin-releasing hormone agonists in the diagnosis of pubertal disorders in girls. Clin Obstet Gynecol. 1993 Sep; 36(3):773-85.
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