 Cholangiocarcinoma
"Cholangiocarcinoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A malignant tumor arising from the intrahepatic bile duct epithelium. It is composed of ducts lined by cuboidal or columnar cells that do not contain bile, with abundant stroma. (From Holland et al., Cancer Medicine, 3d ed, p1455; Stedman, 25th ed)
| Descriptor ID |
D018281
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| MeSH Number(s) |
C04.557.470.200.025.450
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cholangiocarcinoma".
Below are MeSH descriptors whose meaning is more specific than "Cholangiocarcinoma".
This graph shows the total number of publications written about "Cholangiocarcinoma" by people in this website by year, and whether "Cholangiocarcinoma" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 | | 1995 | 0 | 1 | 1 | | 1997 | 1 | 0 | 1 | | 2000 | 1 | 0 | 1 | | 2001 | 2 | 2 | 4 | | 2004 | 2 | 0 | 2 | | 2005 | 3 | 1 | 4 | | 2006 | 3 | 1 | 4 | | 2008 | 1 | 0 | 1 | | 2009 | 2 | 0 | 2 | | 2010 | 3 | 2 | 5 | | 2011 | 1 | 0 | 1 | | 2012 | 2 | 0 | 2 | | 2013 | 1 | 0 | 1 | | 2014 | 3 | 0 | 3 | | 2015 | 4 | 0 | 4 | | 2016 | 2 | 1 | 3 | | 2017 | 1 | 0 | 1 | | 2018 | 1 | 1 | 2 | | 2020 | 2 | 0 | 2 | | 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Cholangiocarcinoma" by people in Profiles.
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Desai N, Pillai AA. The New Era of Liver Transplantation for Cholangiocarcinoma: No Longer Just a 1-Man Show. Liver Transpl. 2022 03; 28(3):355-356.
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Zhu AX, Macarulla T, Javle MM, Kelley RK, Lubner SJ, Adeva J, Cleary JM, Catenacci DVT, Borad MJ, Bridgewater JA, Harris WP, Murphy AG, Oh DY, Whisenant JR, Lowery MA, Goyal L, Shroff RT, El-Khoueiry AB, Chamberlain CX, Aguado-Fraile E, Choe S, Wu B, Liu H, Gliser C, Pandya SS, Valle JW, Abou-Alfa GK. Final Overall Survival Efficacy Results of Ivosidenib for Patients With Advanced Cholangiocarcinoma With IDH1 Mutation: The Phase 3 Randomized Clinical ClarIDHy Trial. JAMA Oncol. 2021 Nov 01; 7(11):1669-1677.
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Ferral H, Alonzo MJ, Datri J, Hogg ME, Marsh R, Talamonti MS. Endovascular management of portal vein obstruction in hepatobiliary cancer patients. J Surg Oncol. 2022 Mar; 125(3):392-398.
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Zhang Q, Ma C, Duan Y, Heinrich B, Rosato U, Diggs LP, Ma L, Roy S, Fu Q, Brown ZJ, Wabitsch S, Thovarai V, Fu J, Feng D, Ruf B, Cui LL, Subramanyam V, Frank KM, Wang S, Kleiner DE, Ritz T, Rupp C, Gao B, Longerich T, Kroemer A, Wang XW, Ruchirawat M, Korangy F, Schnabl B, Trinchieri G, Greten TF. Gut Microbiome Directs Hepatocytes to Recruit MDSCs and Promote Cholangiocarcinoma. Cancer Discov. 2021 05; 11(5):1248-1267.
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Lin A, Alpert L, Hart J, Chapman C, Pillai AA. Lymphoepithelioma-Like Carcinomas: A Rare Variant of Cholangiocarcinoma. Hepatology. 2020 07; 72(1):353-355.
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Abou-Alfa GK, Macarulla T, Javle MM, Kelley RK, Lubner SJ, Adeva J, Cleary JM, Catenacci DV, Borad MJ, Bridgewater J, Harris WP, Murphy AG, Oh DY, Whisenant J, Lowery MA, Goyal L, Shroff RT, El-Khoueiry AB, Fan B, Wu B, Chamberlain CX, Jiang L, Gliser C, Pandya SS, Valle JW, Zhu AX. Ivosidenib in IDH1-mutant, chemotherapy-refractory cholangiocarcinoma (ClarIDHy): a multicentre, randomised, double-blind, placebo-controlled, phase 3 study. Lancet Oncol. 2020 06; 21(6):796-807.
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Abou-Alfa GK, Sahai V, Hollebecque A, Vaccaro G, Melisi D, Al-Rajabi R, Paulson AS, Borad MJ, Gallinson D, Murphy AG, Oh DY, Dotan E, Catenacci DV, Van Cutsem E, Ji T, Lihou CF, Zhen H, Féliz L, Vogel A. Pemigatinib for previously treated, locally advanced or metastatic cholangiocarcinoma: a multicentre, open-label, phase 2 study. Lancet Oncol. 2020 05; 21(5):671-684.
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Pillai A. Mixed Hepatocellular-Cholangiocarcinoma: Is It Time to Rethink Consideration for Liver Transplantation? Liver Transpl. 2018 10; 24(10):1329-1330.
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Gray HJ, Bell-McGuinn K, Fleming GF, Cristea M, Xiong H, Sullivan D, Luo Y, McKee MD, Munasinghe W, Martin LP. Phase I combination study of the PARP inhibitor veliparib plus carboplatin and gemcitabine in patients with advanced ovarian cancer and other solid malignancies. Gynecol Oncol. 2018 03; 148(3):507-514.
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Elshamy M, Presser N, Hammad AY, Firl DJ, Coppa C, Fung J, Aucejo FN. Liver transplantation in patients with incidental hepatocellular carcinoma/cholangiocarcinoma and intrahepatic cholangiocarcinoma: a single-center experience. Hepatobiliary Pancreat Dis Int. 2017 Jun; 16(3):264-270.
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