"Neurofibroma, Plexiform" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A type of neurofibroma manifesting as a diffuse overgrowth of subcutaneous tissue, usually involving the face, scalp, neck, and chest but occasionally occurring in the abdomen or pelvis. The tumors tend to progress, and may extend along nerve roots to eventually involve the spinal roots and spinal cord. This process is almost always a manifestation of NEUROFIBROMATOSIS 1. (From Adams et al., Principles of Neurology, 6th ed, p1016; J Pediatr 1997 Nov;131(5):678-82)
| Descriptor ID |
D018318
|
| MeSH Number(s) |
C04.557.580.600.580.585 C10.551.775.500.750.500 C10.668.829.725.500.600.500
|
| Concept/Terms |
Neurofibroma, Plexiform- Neurofibroma, Plexiform
- Neurofibromas, Plexiform
- Plexiform Neurofibroma
- Plexiform Neurofibromas
- Tumor Royale
- Pachydermatocele
- Pachydermatoceles
- Elephantiasis Neuromatosis
- Elephantiasis Neuromatoses
- Neuromas, Plexiform
- Neuroma, Plexiform
- Plexiform Neuroma
- Plexiform Neuromas
|
Below are MeSH descriptors whose meaning is more general than "Neurofibroma, Plexiform".
Below are MeSH descriptors whose meaning is more specific than "Neurofibroma, Plexiform".
This graph shows the total number of publications written about "Neurofibroma, Plexiform" by people in this website by year, and whether "Neurofibroma, Plexiform" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Neurofibroma, Plexiform" by people in Profiles.
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NF106: A Neurofibromatosis Clinical Trials Consortium Phase II Trial of the MEK Inhibitor Mirdametinib (PD-0325901) in Adolescents and Adults With NF1-Related Plexiform Neurofibromas. J Clin Oncol. 2021 03 01; 39(7):797-806.
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Sirolimus for progressive neurofibromatosis type 1-associated plexiform neurofibromas: a neurofibromatosis Clinical Trials Consortium phase II study. Neuro Oncol. 2015 Apr; 17(4):596-603.
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Expression profiling of 519 kinase genes in matched malignant peripheral nerve sheath tumor/plexiform neurofibroma samples is discriminatory and identifies mitotic regulators BUB1B, PBK and NEK2 as overexpressed with transformation. Mod Pathol. 2013 Jul; 26(7):930-43.
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Expression of MiTF may be helpful in differentiating cellular neurothekeoma from plexiform fibrohistiocytic tumor (histiocytoid predominant) in a partial biopsy specimen. Am J Dermatopathol. 2012 Apr; 34(2):157-60.
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Plexiform neurofibroma of the finger. J Plast Reconstr Aesthet Surg. 2008 Nov; 61(11):1402-3.
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Clinic-based study of plexiform neurofibromas in neurofibromatosis 1. Am J Med Genet. 2000 May 15; 92(2):132-5.