L-Selectin
"L-Selectin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell adhesion molecule and CD antigen that serves as a homing receptor for lymphocytes to lymph node high endothelial venules.
Descriptor ID |
D019041
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MeSH Number(s) |
D12.776.395.550.200.625.903 D12.776.395.550.200.700.510 D12.776.503.843.510 D12.776.543.550.200.625.903 D12.776.543.550.200.700.510 D12.776.543.750.705.877.903 D23.050.301.264.035.850.903 D23.050.301.350.625.903 D23.050.301.350.700.510 D23.101.100.110.850.903
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Concept/Terms |
L-Selectin- L-Selectin
- CD62L Antigen
- Antigen, CD62L
- CD62L Antigens
- L Selectin
- Selectin, L
- TQ1 Antigen
- Antigen, TQ1
- LECAM-1
- Leu-8 Antigen
- Antigen, Leu-8
- Leu 8 Antigen
- Leukocyte Adhesion Molecule, LAM-1
- Leukocyte Adhesion Molecule, LAM 1
- Mel-14 Antigen
- Antigen, Mel-14
- Mel 14 Antigen
- Antigens, CD62L
- LAM-1
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Below are MeSH descriptors whose meaning is more general than "L-Selectin".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Glycoproteins [D12.776.395]
- Membrane Glycoproteins [D12.776.395.550]
- Cell Adhesion Molecules [D12.776.395.550.200]
- Receptors, Lymphocyte Homing [D12.776.395.550.200.625]
- L-Selectin [D12.776.395.550.200.625.903]
- Selectins [D12.776.395.550.200.700]
- L-Selectin [D12.776.395.550.200.700.510]
- Lectins [D12.776.503]
- Selectins [D12.776.503.843]
- L-Selectin [D12.776.503.843.510]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Cell Adhesion Molecules [D12.776.543.550.200]
- Receptors, Lymphocyte Homing [D12.776.543.550.200.625]
- L-Selectin [D12.776.543.550.200.625.903]
- Selectins [D12.776.543.550.200.700]
- L-Selectin [D12.776.543.550.200.700.510]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Lymphocyte Homing [D12.776.543.750.705.877]
- L-Selectin [D12.776.543.750.705.877.903]
- Biological Factors [D23]
- Antigens [D23.050]
- Antigens, Surface [D23.050.301]
- Antigens, Differentiation [D23.050.301.264]
- Antigens, CD [D23.050.301.264.035]
- Receptors, Lymphocyte Homing [D23.050.301.264.035.850]
- L-Selectin [D23.050.301.264.035.850.903]
- Cell Adhesion Molecules [D23.050.301.350]
- Receptors, Lymphocyte Homing [D23.050.301.350.625]
- L-Selectin [D23.050.301.350.625.903]
- Selectins [D23.050.301.350.700]
- L-Selectin [D23.050.301.350.700.510]
- Biological Markers [D23.101]
- Antigens, Differentiation [D23.101.100]
- Antigens, CD [D23.101.100.110]
- Receptors, Lymphocyte Homing [D23.101.100.110.850]
- L-Selectin [D23.101.100.110.850.903]
Below are MeSH descriptors whose meaning is more specific than "L-Selectin".
This graph shows the total number of publications written about "L-Selectin" by people in this website by year, and whether "L-Selectin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1993 | 0 | 2 | 2 | 1999 | 0 | 1 | 1 | 2002 | 1 | 0 | 1 | 2003 | 1 | 1 | 2 | 2004 | 0 | 1 | 1 | 2005 | 0 | 1 | 1 | 2006 | 1 | 1 | 2 | 2007 | 1 | 0 | 1 | 2009 | 1 | 0 | 1 | 2010 | 0 | 1 | 1 | 2011 | 1 | 0 | 1 | 2018 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "L-Selectin" by people in Profiles.
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McCreedy DA, Lee S, Sontag CJ, Weinstein P, Olivas AD, Martinez AF, Fandel TM, Trivedi A, Lowell CA, Rosen SD, Noble-Haeusslein LJ. Early Targeting of L-Selectin on Leukocytes Promotes Recovery after Spinal Cord Injury, Implicating Novel Mechanisms of Pathogenesis. eNeuro. 2018 Jul-Aug; 5(4).
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Chang EK, Eckert MA, Ali MM, Riazifar H, Pone EJ, Liu L, Zhao W. Facile supermolecular aptamer inhibitors of L-selectin. PLoS One. 2015; 10(3):e0123034.
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Rops AL, Loeven MA, van Gemst JJ, Eversen I, Van Wijk XM, Dijkman HB, van Kuppevelt TH, Berden JH, Rabelink TJ, Esko JD, van der Vlag J. Modulation of heparan sulfate in the glomerular endothelial glycocalyx decreases leukocyte influx during experimental glomerulonephritis. Kidney Int. 2014 Nov; 86(5):932-42.
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Moore TV, Clay BS, Cannon JL, Histed A, Shilling RA, Sperling AI. Inducible costimulator controls migration of T cells to the lungs via down-regulation of CCR7 and CD62L. Am J Respir Cell Mol Biol. 2011 Oct; 45(4):843-50.
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Kemp KL, Levin SD, Stein PL. Lck regulates IL-10 expression in memory-like Th1 cells. Eur J Immunol. 2010 Nov; 40(11):3210-9.
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Schuster K, Gadiot J, Andreesen R, Mackensen A, Gajewski TF, Blank C. Homeostatic proliferation of naïve CD8+ T cells depends on CD62L/L-selectin-mediated homing to peripheral LN. Eur J Immunol. 2009 Nov; 39(11):2981-90.
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Welner RS, Pelayo R, Garrett KP, Chen X, Perry SS, Sun XH, Kee BL, Kincade PW. Interferon-producing killer dendritic cells (IKDCs) arise via a unique differentiation pathway from primitive c-kitHiCD62L+ lymphoid progenitors. Blood. 2007 Jun 01; 109(11):4825-931.
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Hall RP, Takeuchi F, Benbenisty KM, Streilein RD. Cutaneous endothelial cell activation in normal skin of patients with dermatitis herpetiformis associated with increased serum levels of IL-8, sE-Selectin, and TNF-alpha. J Invest Dermatol. 2006 Jun; 126(6):1331-7.
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Takei T, Hiraoka M, Nitta K, Uchida K, Deushi M, Yu T, Nitta N, Tsuchiya K, Yumura W, Nihei H, Nakamura Y, Yoshida M. Functional impact of IgA nephropathy-associated selectin gene haplotype on leukocyte-endothelial interaction. Immunogenetics. 2006 Jun; 58(5-6):355-61.
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Macedo C, Donnenberg A, Popescu I, Reyes J, Abu-Elmagd K, Shapiro R, Zeevi A, Fung JJ, Storkus WJ, Metes D. EBV-specific memory CD8+ T cell phenotype and function in stable solid organ transplant patients. Transpl Immunol. 2005 Jun; 14(2):109-16.
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