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Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation.
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Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation.
Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation. Diabetes. 2002 Apr; 51(4):966-76.
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PubMed
subject areas
Adenoviridae
Animals
Cell Division
Cell Line
DNA
Epidermal Growth Factor
Genetic Vectors
Glucose
Insulin Receptor Substrate Proteins
Insulin-Like Growth Factor I
Intracellular Signaling Peptides and Proteins
Islets of Langerhans
Kinetics
MAP Kinase Signaling System
Mitogen-Activated Protein Kinase 1
Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinases
Phosphoproteins
Phosphorylation
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-akt
Receptor, Insulin
Recombinant Proteins
Signal Transduction
Thymidine
Transfection
Transforming Growth Factor alpha
authors with profiles
Christopher J. Rhodes