Prostaglandins PGE(2) and PGI(2) promote endothelial barrier enhancement via PKA- and Epac1/Rap1-dependent Rac activation.

Prostaglandins PGE(2) and PGI(2) promote endothelial barrier enhancement via PKA- and Epac1/Rap1-dependent Rac activation. Exp Cell Res. 2007 Jul 01; 313(11):2504-20.

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subject areas

Adherens Junctions
Animals
Blood-Air Barrier
Cells, Cultured
Cyclic AMP
Cyclic AMP-Dependent Protein Kinases
Cytoskeleton
Dinoprostone
Endothelial Cells
Epoprostenol
Guanine Nucleotide Exchange Factors
Humans
Lung
Male
Mice
Mice, Inbred C57BL
Permeability
Proto-Oncogene Proteins c-vav
rac GTP-Binding Proteins
rac1 GTP-Binding Protein
RNA, Small Interfering
T-Lymphoma Invasion and Metastasis-inducing Protein 1

authors with profiles

Panfeng Fu