 Loratadine
"Loratadine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS) it lacks central nervous system depressing effects such as drowsiness.
| Descriptor ID |
D017336
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| MeSH Number(s) |
D02.455.426.559.847.181.384.340.500 D03.383.621.160.500 D04.615.181.384.340.500
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| Concept/Terms |
Loratadine- Loratadine
- 4-(8-Chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-1-piperidinecarboxylic Acid Ethyl Ester
Alavert- Alavert
- Wyeth Brand of Loratadine
- Loratadine Wyeth Brand
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Below are MeSH descriptors whose meaning is more general than "Loratadine".
Below are MeSH descriptors whose meaning is more specific than "Loratadine".
This graph shows the total number of publications written about "Loratadine" by people in this website by year, and whether "Loratadine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 1 | 0 | 1 | | 1993 | 0 | 1 | 1 | | 1996 | 1 | 0 | 1 | | 1999 | 1 | 0 | 1 | | 2001 | 0 | 1 | 1 | | 2003 | 1 | 0 | 1 | | 2004 | 2 | 0 | 2 | | 2005 | 1 | 1 | 2 | | 2008 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Loratadine" by people in Profiles.
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Shi Z, Wang C, Sun CC. Molecular Origin of the Distinct Tabletability of Loratadine and Desloratadine: Role of the Bonding Area - Bonding Strength Interplay. Pharm Res. 2020 Jun 28; 37(7):133.
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Kamenica E, Naclerio R, Malani A. Advertisements impact the physiological efficacy of a branded drug. Proc Natl Acad Sci U S A. 2013 Aug 06; 110(32):12931-5.
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Baroody FM, Mucha SM, Detineo M, Naclerio RM. Nasal challenge with allergen leads to maxillary sinus inflammation. J Allergy Clin Immunol. 2008 May; 121(5):1126-1132.e7.
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Klemens JJ, Kirtsreesakul V, Luxameechanporn T, Naclerio RM. Acute bacterial rhinosinusitis causes hyperresponsiveness to histamine challenge in mice. Arch Otolaryngol Head Neck Surg. 2005 Oct; 131(10):905-10.
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Bhatia S, Baroody FM, deTineo M, Naclerio RM. Increased nasal airflow with budesonide compared with desloratadine during the allergy season. Arch Otolaryngol Head Neck Surg. 2005 Mar; 131(3):223-8.
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Kirtsreesakul V, Blair C, Yu X, Thompson K, Naclerio RM. Desloratadine partially inhibits the augmented bacterial responses in the sinuses of allergic and infected mice. Clin Exp Allergy. 2004 Oct; 34(10):1649-54.
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Moinuddin R, deTineo M, Maleckar B, Naclerio RM, Baroody FM. Comparison of the combinations of fexofenadine-pseudoephedrine and loratadine-montelukast in the treatment of seasonal allergic rhinitis. Ann Allergy Asthma Immunol. 2004 Jan; 92(1):73-9.
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Haberal I, Corey JP. The role of leukotrienes in nasal allergy. Otolaryngol Head Neck Surg. 2003 Sep; 129(3):274-9.
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Saengpanich S, deTineo M, Naclerio RM, Baroody FM. Fluticasone nasal spray and the combination of loratadine and montelukast in seasonal allergic rhinitis. Arch Otolaryngol Head Neck Surg. 2003 May; 129(5):557-62.
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Kaszuba SM, Baroody FM, deTineo M, Haney L, Blair C, Naclerio RM. Superiority of an intranasal corticosteroid compared with an oral antihistamine in the as-needed treatment of seasonal allergic rhinitis. Arch Intern Med. 2001 Nov 26; 161(21):2581-7.
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