Tandem Mass Spectrometry
"Tandem Mass Spectrometry" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mass spectrometry technique using two (MS/MS) or more mass analyzers. With two in tandem, the precursor ions are mass-selected by a first mass analyzer, and focused into a collision region where they are then fragmented into product ions which are then characterized by a second mass analyzer. A variety of techniques are used to separate the compounds, ionize them, and introduce them to the first mass analyzer. For example, for in GC-MS/MS, GAS CHROMATOGRAPHY-MASS SPECTROMETRY is involved in separating relatively small compounds by GAS CHROMATOGRAPHY prior to injecting them into an ionization chamber for the mass selection.
Descriptor ID |
D053719
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MeSH Number(s) |
E05.196.566.880
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Concept/Terms |
Tandem Mass Spectrometry- Tandem Mass Spectrometry
- Mass Spectrometry, Tandem
- Mass Spectrometry-Mass Spectrometry
- Mass Spectrometry Mass Spectrometry
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Below are MeSH descriptors whose meaning is more general than "Tandem Mass Spectrometry".
Below are MeSH descriptors whose meaning is more specific than "Tandem Mass Spectrometry".
This graph shows the total number of publications written about "Tandem Mass Spectrometry" by people in this website by year, and whether "Tandem Mass Spectrometry" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2007 | 0 | 3 | 3 | 2008 | 1 | 3 | 4 | 2009 | 0 | 6 | 6 | 2010 | 0 | 6 | 6 | 2011 | 3 | 4 | 7 | 2012 | 0 | 7 | 7 | 2013 | 0 | 4 | 4 | 2014 | 1 | 5 | 6 | 2015 | 0 | 3 | 3 | 2016 | 1 | 3 | 4 | 2017 | 2 | 4 | 6 | 2018 | 0 | 8 | 8 | 2019 | 4 | 2 | 6 | 2020 | 1 | 2 | 3 | 2021 | 0 | 3 | 3 |
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Below are the most recent publications written about "Tandem Mass Spectrometry" by people in Profiles.
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Aoullay Z, Van Wijk XMR, Yanhui M, Meddah B, Lynch KL, Cherrah Y, Wu AHB. Development of an LC-MS/MS Method for Measurement of Irinotecan and Its Major Metabolites in Plasma: Technical Considerations. Lab Med. 2022 Jan 06; 53(1):47-52.
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Ochiai K, Shima H, Ikura T, Franke MC, Sievert EP, Sciammas R, Igarashi K. Protocol for in vitro BCR-mediated plasma cell differentiation and purification of chromatin-associated proteins. STAR Protoc. 2021 09 17; 2(3):100633.
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Moorthy GS, Vedar C, Downes KJ, Fitzgerald JC, Scheetz MH, Zuppa AF. Microsampling Assays for Pharmacokinetic Analysis and Therapeutic Drug Monitoring of Antimicrobial Drugs in Children: A Critical Review. Ther Drug Monit. 2021 06 01; 43(3):335-345.
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Ballard PL, Torgerson D, Wadhawan R, Hudak ML, Weitkamp JH, Harris J, Asselin J, Chapin C, Ballard RA, McEvoy CT. Blood metabolomics in infants enrolled in a dose escalation pilot trial of budesonide in surfactant. Pediatr Res. 2021 10; 90(4):784-794.
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Coscia F, Doll S, Bech JM, Schweizer L, Mund A, Lengyel E, Lindebjerg J, Madsen GI, Moreira JM, Mann M. A streamlined mass spectrometry-based proteomics workflow for large-scale FFPE tissue analysis. J Pathol. 2020 05; 251(1):100-112.
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Kang T, Boland BB, Jensen P, Alarcon C, Nawrocki A, Grimsby JS, Rhodes CJ, Larsen MR. Characterization of Signaling Pathways Associated with Pancreatic ß-cell Adaptive Flexibility in Compensation of Obesity-linked Diabetes in db/db Mice. Mol Cell Proteomics. 2020 06; 19(6):971-993.
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Refetoff S, Scherberg NH, Yuan C, Wu W, Wu Z, McPhaul MJ. Free Thyroxine Concentrations in Sera of Individuals with Familial Dysalbuminemic Hyperthyroxinemia: A Comparison of Three Methods of Measurement. Thyroid. 2020 01; 30(1):37-41.
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Chan SL, Yi X, Wysocki E, Bridgman R, Gutierrez J, Mikrut K, Leung EK, Yeo KJ, Miller JL. Development of a Nonradioactive Platelet Serotonin Uptake and Release Assay by Micro-Liquid Chromatography Tandem Mass Spectrometry Using Minimal Blood Volume. Am J Clin Pathol. 2019 11 04; 152(6):718-724.
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Melani RD, Srzentic K, Gerbasi VR, McGee JP, Huguet R, Fornelli L, Kelleher NL. Direct measurement of light and heavy antibody chains using ion mobility and middle-down mass spectrometry. MAbs. 2019 Nov-Dec; 11(8):1351-1357.
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Li G, Eckert MA, Chang JW, Montgomery JE, Chryplewicz A, Lengyel E, Moellering RE. Ultrasensitive, multiplexed chemoproteomic profiling with soluble activity-dependent proximity ligation. Proc Natl Acad Sci U S A. 2019 10 22; 116(43):21493-21500.
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