 Dihydrotestosterone
"Dihydrotestosterone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent androgenic metabolite of TESTOSTERONE. It is produced by the action of the enzyme 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE.
| Descriptor ID |
D013196
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| MeSH Number(s) |
D04.808.054.040.248 D06.472.334.851.968.964
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| Concept/Terms |
Dihydrotestosterone- Dihydrotestosterone
- 5 alpha-Dihydrotestosterone
- 5 alpha Dihydrotestosterone
- Stanolone
- 5-alpha-DHT
- 5 alpha DHT
- Androstanolone
- 17beta-Hydroxy-5alpha-Androstan-3-One
- 17beta Hydroxy 5alpha Androstan 3 One
- 5-alpha Dihydrotestosterone
- Dihydrotestosterone, 5-alpha
Gelovit- Gelovit
- Berenguer Infale Brand of Androstanolone
Andractim- Andractim
- Besins-Iscovesco Brand of Androstanolone
- Besins Iscovesco Brand of Androstanolone
Anaprotin- Anaprotin
- Cuxson Brand of Androstanolone
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Below are MeSH descriptors whose meaning is more general than "Dihydrotestosterone".
Below are MeSH descriptors whose meaning is more specific than "Dihydrotestosterone".
This graph shows the total number of publications written about "Dihydrotestosterone" by people in this website by year, and whether "Dihydrotestosterone" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 2 | 2 | | 1984 | 0 | 1 | 1 | | 1986 | 0 | 1 | 1 | | 1987 | 0 | 1 | 1 | | 1990 | 0 | 1 | 1 | | 1991 | 0 | 1 | 1 | | 1995 | 1 | 1 | 2 | | 1997 | 1 | 0 | 1 | | 1998 | 1 | 1 | 2 | | 1999 | 0 | 3 | 3 | | 2000 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2007 | 0 | 2 | 2 | | 2010 | 0 | 2 | 2 | | 2020 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Dihydrotestosterone" by people in Profiles.
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Gu G, Tian L, Herzog SK, Rechoum Y, Gelsomino L, Gao M, Du L, Kim JA, Dustin D, Lo HC, Beyer AR, Edwards DG, Gonzalez T, Tsimelzon A, Huang HJ, Fernandez NM, Grimm SL, Hilsenbeck SG, Liu D, Xu J, Alaniz A, Li S, Mills GB, Janku F, Kittler R, Zhang XH, Coarfa C, Foulds CE, Symmans WF, Andò S, Fuqua SAW. Hormonal modulation of ESR1 mutant metastasis. Oncogene. 2021 02; 40(5):997-1011.
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Gupta S, Wang Y, Ramos-Garcia R, Shevrin D, Nelson JB, Wang Z. Inhibition of 5alpha-reductase enhances testosterone-induced expression of U19/Eaf2 tumor suppressor during the regrowth of LNCaP xenograft tumor in nude mice. Prostate. 2010 Oct 01; 70(14):1575-85.
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Fitchev PP, Wcislak SM, Lee C, Bergh A, Brendler CB, Stellmach VM, Crawford SE, Mavroudis CD, Cornwell ML, Doll JA. Thrombospondin-1 regulates the normal prostate in vivo through angiogenesis and TGF-beta activation. Lab Invest. 2010 Jul; 90(7):1078-90.
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Wang Y, Gupta S, Hua V, Ramos-Garcia R, Shevrin D, Jovanovic BD, Nelson JB, Wang Z. Prolongation of off-cycle interval by finasteride is not associated with survival improvement in intermittent androgen deprivation therapy in LNCaP tumor model. Prostate. 2010 Feb 01; 70(2):147-54.
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Uemura M, Tamura K, Chung S, Honma S, Okuyama A, Nakamura Y, Nakagawa H. Novel 5 alpha-steroid reductase (SRD5A3, type-3) is overexpressed in hormone-refractory prostate cancer. Cancer Sci. 2008 Jan; 99(1):81-6.
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Salih SM, Jamaluddin M, Salama SA, Fadl AA, Nagamani M, Al-Hendy A. Regulation of catechol O-methyltransferase expression in granulosa cells: a potential role for follicular arrest in polycystic ovary syndrome. Fertil Steril. 2008 May; 89(5 Suppl):1414-21.
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Keegan CE, Vilain E, Mohammed M, Lehoczky J, Dobyns WB, Archer SM, Innis JW. Microcephaly, jejunal atresia, aberrant right bronchus, ocular anomalies, and XY sex reversal. . 2004 Mar 15; 125A(3):293-8.
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Davidson M, Marwah A, Sawchuk RJ, Maki K, Marwah P, Weeks C, Lardy H. Safety and pharmacokinetic study with escalating doses of 3-acetyl-7-oxo-dehydroepiandrosterone in healthy male volunteers. Clin Invest Med. 2000 Oct; 23(5):300-10.
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Deplewski D, Rosenfield RL. Growth hormone and insulin-like growth factors have different effects on sebaceous cell growth and differentiation. Endocrinology. 1999 Sep; 140(9):4089-94.
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Varani J, Dame MK, Wojno K, Schuger L, Johnson KJ. Characteristics of nonmalignant and malignant human prostate in organ culture. Lab Invest. 1999 Jun; 79(6):723-31.
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