 TRPC Cation Channels
"TRPC Cation Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subgroup of TRP cation channels that contain 3-4 ANKYRIN repeats and a conserved C-terminal domain. Members are highly expressed in the CENTRAL NERVOUS SYSTEM. Selectivity for calcium over sodium ranges from 0.5 to 10.
| Descriptor ID |
D050052
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| MeSH Number(s) |
D12.776.157.530.400.901.500 D12.776.543.585.400.901.500
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| Concept/Terms |
TRPC Cation Channels- TRPC Cation Channels
- Cation Channels, TRPC
- Channels, TRPC Cation
- Transient Receptor Potential Channels, Type C
TRP Channel- TRP Channel
- Channel, TRP
- TRP Protein
- Protein, TRP
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Below are MeSH descriptors whose meaning is more general than "TRPC Cation Channels".
Below are MeSH descriptors whose meaning is more specific than "TRPC Cation Channels".
This graph shows the total number of publications written about "TRPC Cation Channels" by people in this website by year, and whether "TRPC Cation Channels" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 2000 | 0 | 1 | 1 | | 2002 | 0 | 2 | 2 | | 2004 | 0 | 3 | 3 | | 2005 | 0 | 2 | 2 | | 2006 | 1 | 0 | 1 | | 2010 | 1 | 1 | 2 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "TRPC Cation Channels" by people in Profiles.
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Bröker-Lai J, Kollewe A, Schindeldecker B, Pohle J, Nguyen Chi V, Mathar I, Guzman R, Schwarz Y, Lai A, Weißgerber P, Schwegler H, Dietrich A, Both M, Sprengel R, Draguhn A, Köhr G, Fakler B, Flockerzi V, Bruns D, Freichel M. Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory. EMBO J. 2017 09 15; 36(18):2770-2789.
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Riazanski V, Gabdoulkhakova AG, Boynton LS, Eguchi RR, Deriy LV, Hogarth DK, Loaëc N, Oumata N, Galons H, Brown ME, Shevchenko P, Gallan AJ, Yoo SG, Naren AP, Villereal ML, Beacham DW, Bindokas VP, Birnbaumer L, Meijer L, Nelson DJ. TRPC6 channel translocation into phagosomal membrane augments phagosomal function. Proc Natl Acad Sci U S A. 2015 Nov 24; 112(47):E6486-95.
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Neuner SM, Wilmott LA, Hope KA, Hoffmann B, Chong JA, Abramowitz J, Birnbaumer L, O'Connell KM, Tryba AK, Greene AS, Savio Chan C, Kaczorowski CC. TRPC3 channels critically regulate hippocampal excitability and contextual fear memory. Behav Brain Res. 2015 Mar 15; 281:69-77.
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Piron M, Villereal ML. Chronic exposure to stress hormones alters the subtype of store-operated channels expressed in H19-7 hippocampal neuronal cells. J Cell Physiol. 2013 Jun; 228(6):1332-43.
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Ben-Mabrouk F, Amos LB, Tryba AK. Metabotropic glutamate receptors (mGluR5) activate transient receptor potential canonical channels to improve the regularity of the respiratory rhythm generated by the pre-Bötzinger complex in mice. Eur J Neurosci. 2012 Jun; 35(11):1725-37.
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Ben-Mabrouk F, Tryba AK. Substance P modulation of TRPC3/7 channels improves respiratory rhythm regularity and ICAN-dependent pacemaker activity. Eur J Neurosci. 2010 Apr; 31(7):1219-32.
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Levitan I, Fang Y, Rosenhouse-Dantsker A, Romanenko V. Cholesterol and ion channels. Subcell Biochem. 2010; 51:509-49.
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Yang X, Farber JP, Wu M, Foreman RD, Qin C. Roles of dorsal column pathway and transient receptor potential vanilloid type 1 in augmentation of cerebral blood flow by upper cervical spinal cord stimulation in rats. Neuroscience. 2008 Apr 09; 152(4):950-8.
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Villereal ML. Mechanism and functional significance of TRPC channel multimerization. Semin Cell Dev Biol. 2006 Dec; 17(6):618-29.
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Zagranichnaya TK, Wu X, Villereal ML. Endogenous TRPC1, TRPC3, and TRPC7 proteins combine to form native store-operated channels in HEK-293 cells. J Biol Chem. 2005 Aug 19; 280(33):29559-69.
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