 Interleukin-2 Receptor alpha Subunit
"Interleukin-2 Receptor alpha Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A low affinity interleukin-2 receptor subunit that combines with the INTERLEUKIN-2 RECEPTOR BETA SUBUNIT and the INTERLEUKIN RECEPTOR COMMON GAMMA-CHAIN to form a high affinity receptor for INTERLEUKIN-2.
| Descriptor ID |
D053645
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| MeSH Number(s) |
D12.776.543.750.705.852.420.320.500 D23.050.301.264.035.401 D23.101.100.110.401
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| Concept/Terms |
Interleukin-2 Receptor alpha Subunit- Interleukin-2 Receptor alpha Subunit
- Interleukin 2 Receptor alpha Subunit
- Antigens, CD25
- CD25 Antigen
- Antigen, CD25
- CD25 Antigens
- IL-2Ralpha
- IL 2Ralpha
- Tac P55 Peptide
- Interleukin-2 Receptor alpha Chain
- Interleukin 2 Receptor alpha Chain
- Interleukin-2 Receptors alpha
- Interleukin 2 Receptors alpha
- Receptors alpha, Interleukin-2
- Interleukin-2Ralpha
- Interleukin 2Ralpha
- alpha-subunit, Receptor, Interleukin-2
- Interleukin-2 Receptor alpha
- Interleukin 2 Receptor alpha
- Receptor alpha, Interleukin-2
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Below are MeSH descriptors whose meaning is more general than "Interleukin-2 Receptor alpha Subunit".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, Interleukin [D12.776.543.750.705.852.420]
- Receptors, Interleukin-2 [D12.776.543.750.705.852.420.320]
- Interleukin-2 Receptor alpha Subunit [D12.776.543.750.705.852.420.320.500]
- Biological Factors [D23]
- Antigens [D23.050]
- Antigens, Surface [D23.050.301]
- Antigens, Differentiation [D23.050.301.264]
- Antigens, CD [D23.050.301.264.035]
- Interleukin-2 Receptor alpha Subunit [D23.050.301.264.035.401]
- Biological Markers [D23.101]
- Antigens, Differentiation [D23.101.100]
- Antigens, CD [D23.101.100.110]
- Interleukin-2 Receptor alpha Subunit [D23.101.100.110.401]
Below are MeSH descriptors whose meaning is more specific than "Interleukin-2 Receptor alpha Subunit".
This graph shows the total number of publications written about "Interleukin-2 Receptor alpha Subunit" by people in this website by year, and whether "Interleukin-2 Receptor alpha Subunit" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 | | 2006 | 1 | 2 | 3 | | 2007 | 1 | 0 | 1 | | 2008 | 2 | 1 | 3 | | 2010 | 2 | 0 | 2 | | 2011 | 0 | 2 | 2 | | 2012 | 1 | 2 | 3 | | 2013 | 2 | 2 | 4 | | 2014 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 | | 2020 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Interleukin-2 Receptor alpha Subunit" by people in Profiles.
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Goldberg AD, Atallah E, Rizzieri D, Walter RB, Chung KY, Spira A, Stock W, Tallman MS, Cruz HG, Boni J, Havenith KEG, Chao G, Feingold JM, Wuerthner J, Solh M. Camidanlumab tesirine, an antibody-drug conjugate, in relapsed/refractory CD25-positive acute myeloid leukemia or acute lymphoblastic leukemia: A phase I study. Leuk Res. 2020 08; 95:106385.
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Owen DL, Mahmud SA, Sjaastad LE, Williams JB, Spanier JA, Simeonov DR, Ruscher R, Huang W, Proekt I, Miller CN, Hekim C, Jeschke JC, Aggarwal P, Broeckel U, LaRue RS, Henzler CM, Alegre ML, Anderson MS, August A, Marson A, Zheng Y, Williams CB, Farrar MA. Thymic regulatory T cells arise via two distinct developmental programs. Nat Immunol. 2019 02; 20(2):195-205.
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Roth TL, Puig-Saus C, Yu R, Shifrut E, Carnevale J, Li PJ, Hiatt J, Saco J, Krystofinski P, Li H, Tobin V, Nguyen DN, Lee MR, Putnam AL, Ferris AL, Chen JW, Schickel JN, Pellerin L, Carmody D, Alkorta-Aranburu G, Del Gaudio D, Matsumoto H, Morell M, Mao Y, Cho M, Quadros RM, Gurumurthy CB, Smith B, Haugwitz M, Hughes SH, Weissman JS, Schumann K, Esensten JH, May AP, Ashworth A, Kupfer GM, Greeley SAW, Bacchetta R, Meffre E, Roncarolo MG, Romberg N, Herold KC, Ribas A, Leonetti MD, Marson A. Reprogramming human T cell function and specificity with non-viral genome targeting. Nature. 2018 07; 559(7714):405-409.
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Golab K, Grose R, Trzonkowski P, Wickrema A, Tibudan M, Marek-Trzonkowska N, Matosz S, Solomina J, Ostrega D, Michael Millis J, Witkowski P. Utilization of leukapheresis and CD4 positive selection in Treg isolation and the ex-vivo expansion for a clinical application in transplantation and autoimmune disorders. Oncotarget. 2016 Nov 29; 7(48):79474-79484.
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Chisholm KM, Merker JD, Gotlib JR, Gitana G, Lefterova M, Zehnder JL, George TI, Arber DA, Ohgami RS. Mast cells in systemic mastocytosis have distinctly brighter CD45 expression by flow cytometry. Am J Clin Pathol. 2015 Apr; 143(4):527-34.
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Marek-Trzonkowska N, Mysliwiec M, Dobyszuk A, Grabowska M, Derkowska I, Juscinska J, Owczuk R, Szadkowska A, Witkowski P, Mlynarski W, Jarosz-Chobot P, Bossowski A, Siebert J, Trzonkowski P. Therapy of type 1 diabetes with CD4(+)CD25(high)CD127-regulatory T cells prolongs survival of pancreatic islets - results of one year follow-up. Clin Immunol. 2014 Jul; 153(1):23-30.
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Colvin SC, Maier B, Morris DL, Tersey SA, Mirmira RG. Deoxyhypusine synthase promotes differentiation and proliferation of T helper type 1 (Th1) cells in autoimmune diabetes. J Biol Chem. 2013 Dec 20; 288(51):36226-35.
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Evaristo C, Alegre ML. IFN-?: The Dr. Jekyll and Mr. Hyde of immunology? Am J Transplant. 2013 Dec; 13(12):3057-8.
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Liu H, Bakthavatsalam R, Meng Z, Li Z, Li W, Perkins JD, Reyes J. PD-L1 signal on liver dendritic cells is critical for Foxp3(+)CD4(+)CD25(+) Treg and liver tolerance induction in mice. Transplant Proc. 2013 Jun; 45(5):1853-5.
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Wang XJ, Leveson-Gower D, Golab K, Wang LJ, Marek-Trzonkowska N, Krzystyniak A, Wardowska A, Millis JM, Trzonkowski P, Witkowski P. Influence of pharmacological immunomodulatory agents on CD4(+)CD25(high)FoxP3(+) T regulatory cells in humans. Int Immunopharmacol. 2013 Jul; 16(3):364-70.
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